antibody

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Introduction to Antibody Structure/Function

Origins of antibodies Product of the adaptive immune system B cells (antibody based immunity) T cells (cell based immunity) Pre-exposure protects against subsequent infection Bacteria viruses toxins Plasma from exposed mice can confer protection to naïve mice Infants protected by maternal antibodies

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Basic Antibody Structure

Basic Antibody Structure • Multiple myeloma = cancerous plasma cells • Monomer = 150000 Mercaptoethanol H + 2 L Papain 2 (45000) 1 (50000) 2 Fab + Fc 1 Constant region- amino acid sequence in the C-terminal regions of the H and L chains is the same 2 Variable region - amino acid sequence in the N-terminal regions of the H and

Are Antibody-Derived macromolecules the mainstay of protein-based therapeutic molecules?
only 51% to 54% identity to the mouse antibody. Despite several back mutations in the Vernier zone, PDF | Antibodies and antibody-derived macromolecules have established themselves as the mainstay in protein-based therapeutic molecules (biologics).
What are polyclonal antibodies?
polyclonal antibodies are a complex mixture of antibodies directed against different epitopes and that differ in their affinity for the antigen. Polyclonal antibodies: antibody preparations from immunized animals. Consist of complex mixtures of different antibodies produced by many different B cell clones

Antibody structure and function Immunoglobulin

Antibodies: Structures types and functions

Antibodies Immunoglobulins Structure & Function Part 1

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PDF	Antibody structure a structural modification of antibody molecules? Structure of Immunoglobulins (Ig ) The four-chain structure of Ig, consisting of two heavy and two light chains

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