HE4 – score ROMA – Cancer de l`ovaire - Divorce


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  • What is the difference between Roma and HE4 ovarian cancer?

    The specificity of ROMA is lower than HE4 (84% compared to 94%). To date, the most efficient biological diagnostic tool to diagnose ovarian cancer is the combination of CA125 and HE4. Ovarian cancer is the 5th worldwide leading cause of death of women due to cancer [ 1 ]. In more than 70% of cases, it is diagnosed at an advanced phase.

  • Is Roma a risk factor for malignancy?

    Also, we have reported sensitivity, specificity, predictive values and AUC in our study. According to our study, the risk of having malignancy is high if the values for ROMA were > 13.3% in premenopausal females and > 76% in postmenopausal females presenting with adnexal masses.

  • Does Roma predict ovarian cancer in postmenopausal women?

    Our study found ROMA as the best marker to differentiate EOC from benign ovarian masses with greater diagnostic accuracy as compared to HE4 and CA125 in postmenopausal women. In premenopausal women, HE4 is a promising predictor of Epithelial ovarian cancer; however, its utilisation requires further exploration.

  • What is the risk of Ovarian Malignancy algorithm (Roma)?

    The risk of ovarian malignancy algorithm (ROMA) incorporates cancer antigen 125 (CA125), human epididymal protein 4 (HE4), and menopausal status to assign women that present with an adnexal mass into a high-risk or low-risk group for finding an ovarian malignancy.

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HE4 – score ROMA – Cancer de l`ovaire

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