b cell activation requires quizlet
What are the steps of B-cell activation quizlet?
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antigen recognition-B cell exposed to antigen and binds with matching complementary.antigen presentation-B cell displays epitope, Helper T cell binds secretes interleukin.clonal selection= interleukin stimulates B cell to divide.differentiation=become memory or plasma cells.attack- plasma cells secrete antibody.Which of the events are required for B-cell activation?
To become activated to produce antibodies, B cells must first recognize specific antigen through the B-cell receptor (BCR).
This specific binding event initiates intracellular signaling leading to altered gene expression, reorganization of the B-cell cytoskeleton, and antigen internalization.B cells are activated by two temporally distinct signals, the first provided by antigen binding to the B cell antigen receptor (BCR) and the second by T helper cells.
What does B-cell activation require?
B-cell activation by many antigens, especially monomeric proteins, requires both binding of the antigen by the B-cell surface immunoglobulin—the B-cell receptor—and interaction of the B cell with antigen-specific helper T cells.
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12-Sept-2017 Activated B cells produce interleukin 6 (IL-6) a proinflammatory ... whether B cell–derived IL-6 is required to trigger autoimmune Gcs has ... |
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interleukin (step 2), the active portion of the interleukin is released from the cell An interleukin is a signaling molecule that can activate the immune response |