the constant field equation
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Box 24 The GHK equations 241 An electrical circuit approximation
Because of the assumption of a constant electric field in the membrane the GHK equations are sometimes referred to as the constant-field equations 2 4 1 |
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185 Since Goldman [1] published his paper in 1943 the constant
The constant field equation is then obtained from the added assumption of zero net current flow across the membrane If only univalent ions have nonzero |
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19 INTRODUCTION The Goldman equation as originally derived [ 1
The Goldman equation as originally derived [ 12] depended on the assumptions of a constant field across the membrane zero net current flow across the membrane |
What is the GFK equation?
The Goldman–Hodgkin–Katz flux equation (or GHK flux equation or GHK current density equation) describes the ionic flux across a cell membrane as a function of the transmembrane potential and the concentrations of the ion inside and outside of the cell.
What is the GHK equation explained?
The GHK equation is founded on the premise that the transmembrane ion transport across the plasma membrane is responsible for the membrane potential generation and that the membrane permeability to the individual mobile ions governs the membrane potential behavior.
What is the Goldman's equation?
The Goldman–Hodgkin–Katz voltage equation, sometimes called the Goldman equation, is used in cell membrane physiology to determine the reversal potential across a cell's membrane, taking into account all of the ions that are permeant through that membrane.
In the GHK model of the membrane, permeability is proportional to the diffusion coefficient, DX, defined in Fick's first law (Equation 2.2).
Hille (2001) discusses the relationship in more detail.
The GHK equation predates the notion of membrane channels and treats the membrane as homogeneous.
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The enduring legacy of the “constant-field equation” in membrane
of concentration and voltage gradients to the current density carried by single ionic species. Today we know it as the constant-field current equation (Eq. |
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185 Since Goldman [1] published his paper in 1943 the constant
constant field equation holds if the uniform charge density in the mem- brane is sufficient to exclude any coions from the membrane. Recently. Arndt et al. |
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Derivation of the Goldman Equation
The Goldman equation or constant-field equation |
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Extended “Constant Field” equations: an electrodiffusion model of
Nov 27 2017 The “constant field” or “Goldman-Hodgkin and Katz” current equation is a commonly accepted analytic model of electrodiffusion in channels. |
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(1) Modified standard Einstein field equations and cosmological
Jan 22 2017 Keywords: general relativity |
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Derivation of Einsteins field equation
Stress-energy tensor. Conservation of energy and momentum. 29 March—Einstein's discovery of the field equation è Derivation of the Field Equations. |
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Dynamically orthogonal field equations for continuous stochastic
Sep 24 2009 By hypothesizing a decomposition of the solution field into a mean and stochastic dynamical component |
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185 Since Goldman [1] published his paper in 1943 the constant
constant field equation holds if the uniform charge density in the mem- brane is sufficient to exclude any coions from the membrane. Recently. Arndt et al. |
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On the Non-Existence of Regular Stationary Solutions of Relativistic
It is shown that the field equations of the relativistic gravitational theory and of its five-dimensional generalization do not admit any non-singular |
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185 Since Goldman [1] published his paper in 1943, the constant
constant field equation holds if the uniform charge density in the mem- brane is sufficient to exclude any coions from the membrane Recently Arndt et al |
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The Hodgkin–Huxley Equations
Goldman, Hodgkin, and Katz came up with this simplified model called the constant-field equation They assumed (1) the electric field across the lipid membrane is constant, (2) the Nernst–Planck equation holds within the membrane, and (3) the ions all move independently |
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Chapter VI DETERMINATION OF RESTING POTENTIAL A Modified
constant field equation eq 2 where PK , PNa , and P C1 are the membrane permeabilities for K+, Na+, and CI-, respectively The PK [Kli product, for example, is |
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The Numerical Solution of the Time-Dependent Nernst - CORE
equations can be set out When there are several ion species, one muststill solve a transcendental equation to relate ion concentrations and the electrical field, |
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Transport Equations and Criteria for Active Transport Department of
goes to the Nernst equation for that ion Figure 8a shows the voltage and concen- tration profile through the membrane un- der the constant field assumption |
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Application of the Poisson–Nernst–Planck equations to the
Abstract The Poisson–Nernst–Planck (PNP) equations are applied to model the migration test and to approximate the electric field by a constant equal to the |
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