antibiotic classes and coverage chart pdf


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Antibiotic Adverse Reactions Drug Interactions Clinical Pearls Penicillins Penicillin G oxacillin ampicillin amoxicillin GI upset (nausea diarrhea) Hypersensitivity reactions Leukopenia thrombocytopenia (rare) Neurologic (altered mental status seizures) Interstitial nephritis Hepatotoxicity (oxacillin) None

  • Which antibiotic classes cover both Gram-positive and Gram-negative bacteria?

    All but 4 of the antibiotic classes cover both gram-positive and gram-negative bacteria. Therefore, if you remember those 4 classes, then you will know the others will cover both gram-positive and gram-negative organisms. Below are some tricks to remember what those classes are.

  • Do outpatient antibiotic prescription rates vary by antibiotic class?

    Outpatient antibiotic prescription rates vary by antibiotic class. This graph displays national outpatient antibiotic prescriptions dispensed in U.S. community pharmacies per 1,000 population by antibiotic class over time.

  • What are antibiotic classes?

    Antibiotic class defines a set of related antibiotics. State-level rates of penicillins, macrolides, cephalosporins, and fluoroquinolones are displayed. Also displayed are all antibiotic classes, which include these four classes plus additional classes not available for release at the state level.

  • How should Clinicians choose antibiotics for serious infections?

    In general, clinicians should try to use antibiotics with the narrowest spectrum of activity and for the shortest duration. Cultures and antibiotic susceptibility testing are essential for selecting a drug for serious infections.

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