a review of the global epidemiology of scrub typhus

What is the global scenario of scrub typhus?
Scrub typhus is a serious public health problem in the Asia-Pacific area.
There is an estimated one million new scrub typhus infections each year, and over one billion people around the world are at risk.
Without appropriate treatment, the case fatality rate of scrub typhus can reach 30% or even higher._{3 nov. 2017}
Scrub typhus is a killer disease where disseminated vasculitic and perivascular inflammatory lesions result in end-organ injury.
Even though the disease shows dramatic response to appropriate antibiotics, these serious complications can occur and most of them proved to be fatal.

What is the incidence and prevalence of scrub typhus?

Currently, it is estimated that about 1 million cases of scrub typhus occur annually and that as many as 1 billion people living in endemic areas may have been infected by O tsutsugamushi at some time.

What is scrub typhus review?

It is an acute febrile illness with the characteristic findings of high fever, maculopapular rash, lymphadenopathy, eschar, headache, myalgia, cough, sore throat, and gastrointestinal symptoms. [1,2] It is easy to be misdiagnosed if it is not considered, and is a unique feature of infection in endemic areas.

It threatens one billion people globally, and causes illness in one million people each year. Caused by Orientia tsutsugamushi, scrub typhus can result in severe multiorgan failure with a case fatality rate up to 70% without appropriate treatment.

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