1/2 normal saline for hypernatremia


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  • How does sodium chloride affect hypernatremia?

    The retention of 1 liter of 0.9 percent sodium chloride will decrease the serum sodium concentration by only 0.22 mmol per liter ( [154-162]÷ [35+1]=-0.22). Although the sodium concentration of the infusate is lower than the patient's serum sodium concentration, it is not sufficiently low to alter the hypernatremia substantially.

  • How much water is needed to treat hypernatremia?

    Total Body Water [0.6 in men and 0.5 in women x body weight (kg)] x [ (plasma sodium/140) -1] It is important to remember that rapid correction of hypernatremia can lead to cerebral edema because water moves from the serum into the brain cells. The goal is to decrease serum sodium by not more than 12 meq in 24 hours.

  • What is a safe rate of correction for hypernatremia?

    To be safe, the rate of correction should not exceed 12 mEq/liter/day. Hypernatremia, defined as a rise in the serum sodium concentration to a value exceeding 145 mmol per liter, is a common electrolyte disorder. Because sodium is a functionally impermeable solute, it contributes to tonicity and induces the movement of water across cell membranes.

  • What does hypernatremia mean?

    Hypernatremia is defined as a serum sodium concentration of greater than 145 meq/l. This activity reviews the causes and presentation and highlights the role of the interprofessional team in its management Review the causes of hypernatremia. Describe the evaluation of a patient with hypernatremia. Summarize the treatment of hypernatremia.

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