1/2 normal saline tonicity


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  • What is half normal saline?

    Half normal saline (.45% NS) has half the tonicity of Normal saline. This means Half-NS is hypotonic, so the IV fluid has a lower osmolarity than the fluid inside the cells. This means that half normal saline will cause fluid to shift inside the cells, causing the cells to swell. This can be good in certain situations, and very bad in others.

  • How much saline should a patient take?

    Use caution with heart failure or end-stage renal disease, and those on dialysis or in acute fluid overload should probably not receive IV fluids. A large amount of Normal Saline (3-5+ liters) can cause significant hyperchloremic non-anion gap metabolic acidosis, especially if the patient has renal failure.

Tonicity

Tonicity

Hypertonic Hypotonic and Isotonic Solutions!

Hypertonic Hypotonic and Isotonic Solutions!

Hypotonic isotonic and hypertonic solutions (tonicity)  Khan Academy

Hypotonic isotonic and hypertonic solutions (tonicity) Khan Academy

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