acetic acid and salicylic acid reaction
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1 University of Wisconsin Chemistry 116 Preparation and
To make acetylsalicylic acid the -OH group of the salicylic acid reacts with acetic acid to produce the ester and water This reaction like most |
Acetylation of salicylic acid forms aspirin in acidic medium.
What is the esterification reaction of salicylic acid and acetic acid?
The preparation consists of an esterification reaction catalyzed by acid (H2SO4 or H3PO4), where salicylic acid treated with acetic anhydride gives acetylsalicylic acid (aspirin).
In this reaction, a hydroxyl group is converted to an ester, with acetic acid as a byproduct.
What is the reaction between salicylic acid and acetic anhydride?
Aspirin can be made in the laboratory by reacting acetic anhydride (C4H6O3) with salicylic acid (C7H6O3) to form aspirin (C9H8O4) and acetic acid (C2H4O2).
What happens when salicylic acid react with acetyl chloride?
Acetyl chloride reacts with Salicylic acid vigorously in the presence of pyridine to form acetylsalicylic acid or the aspirin .
Pyridine is used in the reaction because the nitrogen in the pyridine is a nucleophilic catalyst.
Aspirin can also be formed by the reaction of salicylic acid and acetic anhydride.
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1 University of Wisconsin Chemistry 116 Preparation and
salicylic acid reacts with acetic acid to produce the ester and water. This reaction like most esterification reactions |
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Experiment 8 – Synthesis of Aspirin
(acetylsalicylic acid also known as aspirin) was shown to be much less Aspirin can be made by reacting salicylic acid with acetic acid in the presence ... |
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Experiment 5 - Synthesis of Aspirin
In the presence of moisture aspirin may decompose (hydrolysis) into salicylic acid and acetic acid. This reaction is the reverse of the synthesis reaction. The |
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Chapter 5 Carboxylic Acids and Esters
Learn the major chemical reaction of carboxylic acids and esters and learn how to Produced by reacting salicylic acid with acetic. |
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The Synthesis of a Medicinal Agent- Aspirin By Walter Scharf and
It was eventually discovered that salicylic acid is the portion of these complete reaction in the preparation of an acetate ester is to use acetic. |
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Ester Synthesis Lab (Student Handout)
Esters are produced by the reaction between alcohols and carboxylic acids. For example reacting ethanol with acetic acid to give ethyl acetate is shown |
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Colorimetric Determination of Iron with Salicylic Acid
the effects of diverse ions. THE reaction between salicylic acid and ferric ion in acetic acid solution to give an amethyst coloration has. |
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Percent Yields from Reactions
Salicylic acid reacts with acetic anhydride to form aspirin acetylsalicylic acid. If the percent yield in this reaction is 78.5% |
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Practical Lab Manual of Pharmaceutical Organic Chemistry - II
Salicylic Acid by Nitration Reaction . Insoluble in water and soluble in 85 % acetic acid and ethanol. 3. Boiling point is about 117 oC. |
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Separation of Salicylic Acid Impurities with Different Acid Mobile
acetic acid change the selectivity of the separation of sal- It is acidified to give the desired salicylic acid. The main reaction is shown in Figure 1; ... |
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8-Synthesis of Aspirin
Aspirin can be made by reacting salicylic acid with acetic acid in the presence of an acid catalyst The phenol group on the salicylic acid forms an ester with the carboxyl group on the acetic acid However, this reaction is slow and has a relatively low yield |
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Experiment 5 - Synthesis of Aspirin
To prepare aspirin, salicylic acid is reacted with an excess of acetic anhydride A small amount of a strong acid is used as a catalyst which speeds up the reaction |
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Esterification of Salicylic Acid - Westfield State University
Thus, salicylic acid can react with nucleophilic molecules like methanol in addition to reacting with electrophilic molecules like acetic anhydride The reaction of |
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Synthesis of Aspirin
Reaction OH OH O salicylic acid O O O acetic anhydride O OH HO O O acetyl salicylic acid (aspirin) OH O acetic acid H2SO4 heat + + |
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Aspirin synthesis for AS/A2 Level chemistry - University of Reading
acetic anhydride OH O OH salicylic acid OH O C H Using familiar A' level chemistry, you will produce aspirin using an esterification reaction with ethanoic |
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Synthesis of Aspirin - Carbon
Figure 5: Acetylation of salicylic acid Risk Assessment Acetylsalicylate and salicylic acid are combustible and harmful if swallowed Acetic anhydride is corrosive, |
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Experiment 12 - Organic Chemistry
In this experiment, you will use salicylic acid, acetic anhydride water Un- reacted acetic anhydride will be hydrolyzed to vinegar and 85 phosphoric acid will |
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Synthesis of Aspirin - Bellevue College
In this experiment you will synthesize aspirin from acetic anhydride and salicylic acid using phosphoric acid as a catalyst to speed up the reaction (it is not a |
