acetylation organic chemistry


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  • What is the reagent of acetylation?

    Acetylation reagents
    Acetic anhydride.
    This reagent is common in the laboratory; its use cogenerates acetic acid.
    Acetyl chloride.
    This reagent is also common in the laboratory, but its use cogenerates hydrogen chloride, which can be undesirable.

  • What is the method of acetylation?

    Traditionally, acetylation of amines is conducted by the treatment of the solution of an amino compound with an acid anhydride or acid chloride in the presence of pyridine and a solvent such as ether or dichloromethane.

  • N-acetylation is a conjugation reaction of relevance to a number of carcinogens, particularly aromatic amines.
    From: Encyclopedia of Environmental Health, 2011.

Acetylation is an organic esterification reaction using acetic acid in chemistry. An acetyl group is introduced into a chemical molecule. These chemicals are known as acetate esters or just acetates. The opposite reaction, deacetylation, is the removal of an acetyl group from a chemical molecule.
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