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PDF THE SOCIETY FOR THE PSYCHOLOGY OF SEXUAL ORIENTATION AND

Gender Dysphoria: Gender dysphoria can refer to the clinical diagnosis in the DSM-5 or can be used to describe the feeling of distress associated with the incongruence between one’s gender and sex assigned at birth Gender dysphoria can be related to one’s body or to how one’s gender is perceived socially Gender Euphoria: A feeling of

Introduction

Nearest neighbor approaches were developed to predict the folding stabilities of nucleic acid secondary structures (1). These parameter sets utilize empirical rules, generally derived from optical melting experimental data, as the basis of the predictions. For RNA, rules exist for predicting both free energy and enthalpy change of Watson–Crick heli

Website Organization

The NNDB is built using a set of static html, specifically XHTML 1.0 transitional pages with a page hierarchy shown in Figure 1. Text is encoded in Unicode (utf-8) to facilitate display of equations in pages with diverse browsers running on diverse operating systems. The top-level page provides access to a help page, available parameter sets and a

Website Content

The first release of the NNDB contains the RNA folding rules assembled in 1999 and 2004 (2–5). These rules represent the most recent set of parameters and a prior set that is widely used in software packages. Because folding rules are derived to work as a set, the two versions of rules and values should not be mixed and the website hierarchy reinfo

Discussion

The NNDB is designed to provide a convenient location for assembling parameter sets for predicting the stability of nucleic acid secondary structures. It is modular in design, which facilitates its future expansion to contain additional parameter sets. Furthermore, the web format makes it feasible to provide extensive tutorials for utilizing the pa

Funding

The creation of the NNDB was supported by United States National Institutes of Health grants GM076485 to D.H.M. and GM22939 to D.H.T. Funding for open access charge: United States National Institutes of Health. academic.oup.com

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