Elecsys CMV IgG Avidity


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PDF Elecsys CMV IgG

A positive IgM result in combination with a low avidity index for IgG is a strong indication of a primary CMV infection within the last 4 months The diagnosis 

PDF Elecsys CMV IgG

performed e g CMV IgM and CMV IgG avidity A positive IgM result in combination with a low avidity index for IgG is a strong indication of a primary CMV 

  • How do you read CMV IgG results?

    A high level of IgG is not as important as a rising level.
    If there is a 4-fold increase in IgG between the first and second sample, then you have an active CMV infection (primary or reactivated).
    A positive CMV IgM and negative IgG means you may have very recently been infected.

  • cmv viral load normal range
    The IgG for CMV normal range is 620 to 1400 mg/dl.
    If the reading is above this threshold, then you will need to consult a doctor to prevent any unwanted symptoms or infections.
    This action is especially crucial for pregnant mothers or parents planning to have a child.

  • What is high avidity of IgG?

    Avidity is defined as the strength of binding between immunoglobulin G (IgG) and its specific target epitope.
    IgG of high avidity is established during affinity maturation.
    Failure to achieve high avidity IgG may result in a lack of protective immunity towards infection and disease.

  • What does CMV IgG avidity mean?

    IgG avidity assays measure the binding strength between IgG antibodies and virus that can help distinguish a primary CMV infection from a past infection.
    Following primary CMV infection, IgG antibodies have low binding strength (low avidity) then over 2-4 months mature to high binding strength (high avidity).

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