acyl coa thioester hydrolase
Acetyl-CoA hydrolase (Ach1p), catalyzing the hydrolysis of acetyl-CoA, is presumably involved in regulating intracellular acetyl-CoA or CoASH pools; however, its intracellular functions and distribution remain to be established.
What do acyl hydrolases do?
Long-chain acyl-CoA hydrolases are a group of enzymes that cleave acyl-CoAs into fatty acids and coenzyme A (CoA-SH).
Because acyl-CoAs participate in numerous reactions encompassing lipid synthesis, energy metabolism and regulation, modulating intracellular levels of acyl-CoAs would affect cellular functions.
What does acyl-CoA dehydrogenase do?
Acyl-CoA dehydrogenases (ACADs) are a class of enzymes that function to catalyze the initial step in each cycle of fatty acid β-oxidation in the mitochondria of cells.
Their action results in the introduction of a trans double-bond between C2 (α) and C3 (β) of the acyl-CoA thioester substrate.
Is acyl-CoA a thioester?
Acyl-CoAs are a family of metabolic intermediates comprised of an acyl group linked by a thioester bond to coenzyme A.
Identification and Characterization of Mitochondrial Acetyl
drial acetyl-CoA hydrolase activity among different plant species CoA thioester was measured directly with the DTNB assay. |
Studies on the hydrolysis and utilization of long chain acyl CoA
Acyl CoA thioester "hydrolase" activity exhibited by liver microsomal preparations using a spectrophotometric assay for released CoA has been shown to. |
Medium chain acyl-thioester hydrolase activity in goat and rabbit
Feb 28 1978 Summary: The goat mammary gland fatty acid synthetase hydroly- sed both medium (CS:O |
Purification and characterization of an extramitochondrial acetyl
Dec 24 1979 A rat liver acetyl-coenzyme A hydrolase has been purified to homogeneity. ... acyl-CoA thioesters is strengthened by the present studies. |
Biosynthesis of 2-Heptanone a Volatile Organic Compound with a
Oct 26 2021 using acyl-CoA thioester hydrolase QBO55937 as the input to search for potential ho- mologs in bacterial species populating apiaries. |
Long-Chain Acyl-CoA Hydrolase from Rat Brain Cytosol: Purification
Nov 1 1995 acyl-CoA thioesters to free fatty acids and CoASH. In lysis of fatty acyl-CoA thioesters. We purified this en- view of the importance of ... |
Fatty-Acid Synthesis in Lactating-Goat Mammary Gland
involves an activation of the medium-chain acyl-thioester hydrolase within the fatty acid synthetase gland fatty acid synthetase towards acyl-CoA model. |
Report
Acyl-CoA thioesterases are referred to in the literature as acyl-CoA hydrolases but as the reaction carried out by these enzymes is the cleavage of a thioester |
Interaction of S-acyl fatty acid synthase thioester hydrolase with fatty
Feb 10 2022 synthesis of c16 fatty acids from acetyl-coA and malonyl-CoA ... acid synthase thioester hydrolase (thioesterase) was prepared from. |
Fattyâ•Acid Synthesis in Lactatingâ•Goat Mammary Gland 1
Acetyl-CoA was synthesized as previously malonyl-CoA generated by acetyl-CoA carboxylase ... acyl-thioester hydrolases developed by Libertini et al. |
The Synthesis and Hydrolysis of Long-Chain Fatty Acyl-Coenzyme A
Thioesters by Soluble and Microsomal Fractions from the Brain fatty acyl-CoA hydrolase (EC 3 1 2 2) were measured in soluble and microsomal fractions |
Molecular cloning and functional expression of human cytosolic
A cDNA encoding human cytosolic acetyl-CoA hydrolase (CACH) was isolated from a human Enzymes: acetyl-CoA hydrolase (EC 3 1 2 1); acyl-CoA thioesterase (EC 3 1 2 2); brain cytosolic acyl-coenzyme A thioester hydrolase J |
Role of ACOT7 in Arachidonic Acid Production and Inflammation
cleaving the thioester bond of activated C20:4-CoA in the general reaction ACOT7 is also known as brain acyl-CoA hydrolase (BACH) and has been purified |
Medium chain acyl-thioester hydrolase activity in goat and rabbit
28 fév 1978 · gland only hydrolysed long chain length acyl CoA esters The medium chain acyl -thioester hydrolase activity of goat mammary gland fatty |
Long-Chain Acyl-CoA Hydrolase from Rat Brain - ScienceDirect
1 nov 1995 · lysis of fatty acyl-CoA thioesters We purified this en- view of the importance of acyl-CoA in lipid biosynthesis zyme, referred to as ACH, from the |
Studies on the hydrolysis and utilization of long chain acyl CoA
Acyl CoA thioester "hydrolase" activity exhibited by liver microsomal preparations using a spectrophotometric assay for released CoA has been shown to |