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Acetylcholine (ACh) is critical for communication between neurons and muscle at the neuromuscular junction is in-volved in direct neurotransmission in autonomic ganglia and has been implicated in cognitive processing arousal and attention in the brain (1) Cholinergic transmission can occur through muscarinic (G protein-coupled) or

  • How acetylcholine is broken down?

    Acetylcholine in the synapse is broken down by an enzyme called acetylcholinesterase into choline and acetate. These products are reabsorbed and recycled so they can be used again in transmitting another chemical message. What does acetylcholine (ACh) do? Acetylcholine has many roles.

  • Is acetylcholine a neurotransmitter?

    Acetylcholine (ACh) is an important neurotransmitter that plays a role in brain functions, such as memory, and body functions, such as muscle contractions to move your muscles. Low levels of acetylcholine are associated with memory issues and muscle disorders.

  • Where is acetylcholine found?

    Acetylcholine is found in your central nervous system (CNS), your brain and spinal cord, as well as in your peripheral nervous system (the nerves that branch out from your CNS and connect with all other parts of your body, including muscles and organs). Where does acetylcholine (ACh) work?

  • Why is acetylcholine called cholinergic?

    The name "acetylcholine" is derived from its chemical structure, as it is an ester of acetic acid and choline. Tissues of the body that use this chemical messenger or are responsive to it are referred to as cholinergic. There is a class of chemicals called anticholinergics that interfere with acetylcholine's action on tissues as well.

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