cholecalciferol ampoule


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PDF Colecalciferol (Cholecalciferol)

In an observational study of 92 infants with cholestasis colecalciferol or ergocalciferol 1200 units increased by increments of 1200 units to 8000 units orally daily or alternatively calcitriol at 0 05 to 0 20 mg/kg per day did not achieve target 25-hydroxy vitamin D >50 nmol/L in all infants (4) [LOE

PDF VITAMIN D ORAL SOLUTION

Loading dose of 8 ampoules 5000 mcg (200000 IU) followed by 4 ampoules 2500 mcg (100000) monthly for two months (total treatment course 16 ampoules 10000 mcg (400000 IU) Serum levels of 25-hydroxycalciferol and calcium should be monitored after initiation of treatment

PDF Cholecalciferol (Vitamin D3) 5mg molecule with one ring

The ampoule of Vitamin D3 Cholecalciferol can be administered through - Oral route or - IM Route Infants receiving milk enriched with Vitamin D: 0 5ml or ½ ampoule (100000 IU) every 6 months Infants breastfeeding and up to 5 years of age and do not receive milk enriched with vitamin D: 1ml or 1 ampoule (200000 IU) every 6 months

  • Is Cholecalciferol a teratogenic drug?

    The FDA classified cholecalciferol as a pregnancy drug category C under its prior pregnancy classification system, indicating that teratogenicity risks cannot be ruled out, and clinicians should only use this agent when benefits outweigh risks.

  • Is Cholecalciferol soluble in water?

    Physicochemical properties: Cholecalciferol is white or almost white crystals, insoluble in water, freely soluble in ethanol (96%) and trimethylpentane and in fatty oils.

  • What are the off-label indications for cholecalciferol?

    The labeled indication for cholecalciferol is dietary supplementation. The off-label indications for cholecalciferol include hypothyroidism, prevention of osteoporosis, and Vitamin D insufficiency/ deficiency in both healthy patients or those with chronic kidney disease (CKD).

  • What does cholecalciferol do?

    Access free multiple choice questions on this topic. Cholecalciferol, also known as vitamin D3, is a secosteroid produced by the skin and can also be present in certain foods such as dairy products, eggs, and fish. Its primary function is to maintain normal calcium and phosphate levels in the serum.

Therapeutic Action

Vitamin necessary for the intestinal absorption of calcium and phosphate and for normal bone calcification medicalguidelines.msf.org

Forms and Strengths

10 000 IU/ml oral solution, in 10 ml vial50 000 IU/ml oral solution, in 2 ml ampoule (100 000 IU) medicalguidelines.msf.org

Dosage and Duration

Colecalciferol and ergocalciferol are used at the same doses: Prevention of vitamin D deficiencies 1. Term neonate: 400 to 800 IU once daily until 6 months of age 2. Term neonate in contexts of high prevalence of vitamin D deficiency: 600 to 1200 IU once daily until 6 months of age 3. Pregnant woman: 100 000 IU single dose (one 2 ml ampoule) in the

Contra-indications, Adverse Effects, Precautions

Do not administer to patients with hypercalcaemia, hypercalciuria, calcic lithiasis, severe renal impairment.Stop treatment if signs of overdosage occur: headache, anorexia, nausea, vomiting, increased thirst, polyuria.Avoid combination with thiazide diuretics, e.g. hydrochlorothiazide (decreased urinary calcium excretion).Monitor, if possible, calcaemia and calciuria during curative treatment. medicalguidelines.msf.org

Remarks

The number of IU per drop of oral solution varies according to manufacturers. Check instructions for use.Preferably use the vials of oral solution that, once opened, keep for 6 months.During the first 3 months of curative treatment, administer a supplement of 500 mg of calcium once daily. medicalguidelines.msf.org

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