isotonicity calculation pdf


  • How do you calculate isotonicity?

    Calculations for preparation of isotonic solution:
    multiply the quantity of each drug in the prescription by it's sodium chloride equivalent E , and subtract this value from the concentration of sodium chloride which is isotonic with body fluids (0.9 gm per 100 ml).
  • How much NaCl to make 50 mL of isotonic solution?

    50 x 0.009 = 0.45 g of sodium chloride in 50 mL of an isotonic sodium chloride solution • Step 3.
  • What is isotonicity with example?

    It may also pertain to a condition or property of a solution that has the same tonicity as the other solution with which it is compared. For example, blood serum is isotonic to a physiologic salt solution. Solutions that have the same tonicity will result in no net flow of water across the cell membrane.
  • Isotonic solution: A solution that has the same salt concentration as cells and blood. Isotonic solutions are commonly used as intravenously infused fluids in hospitalized patients.
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