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TB Elimination

BCG Vaccine Introduction BCG or bacille Calmette-Guérin is a vaccine for tuberculosis (TB) disease Many foreign-born persons have been BCG-vaccinated BCG is used in many countries with a high prevalence of TB to prevent childhood tuberculous meningitis and miliary disease However BCG is not generally recommended for use in the United

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Introduction

BCG, or bacille Calmette-Guerin, is a vaccine for tuberculosis (TB) disease. Many foreign-born persons have been BCG-vaccinated. BCG is used in many countries with a high prevalence of TB to prevent childhood tuberculous meningitis and miliary disease. However, BCG is not generally recommended for use in the United States because of the low risk of

Recommendations

Children. BCG vaccination should only be considered for children who have a negative tuberculin skin test and who are continually exposed, and cannot be separated from, adults who 1. Are untreated or ineffectively treated for TB disease (if the child cannot be given long-term treatment for infection); or 2. Have TB caused by strains resistant to is

Contraindications

Immunosuppression.BCG vaccination should not be given to persons who are immunosuppressed (e.g., persons who are HIV infected) or who are likely to become immunocompromised (e.g., persons who are candidates for organ transplant). Pregnancy.BCG vaccination should not be given during pregnancy. Even though no harmful effects of BCG vaccination on the

Testing For TB in Bcg-Vaccinated Persons

The tuberculin skin test (TST) and blood tests to detect TB infection are not contraindicated for persons who have been vaccinated with BCG. Tuberculin Skin Test (TST).BCG vaccination may cause a false-positive reaction to the TST, which may complicate decisions about prescribing treatment. The presence or size of a TST reaction in persons who have

Treatment For LTBI in Bcg-Vaccinated Persons

Treatment of LTBI substantially reduces the risk that TB infection will progress to disease. Careful assessment to rule out the possibility of TB disease is necessary before treatment for LTBI is started. Evaluation of TST reactions in persons vaccinated with BCG should be interpreted using the same criteria for those not BCG-vaccinated. Persons in

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