Annotation and Quantitation of Sn-Positional Isomers
The fragmentation efficiency into sn-1 and sn-2 product ions is vastly different. Specifically, the different abundances of the sn-1 and sn-2 diagnostic product ions in MS4 indicate that there are competing dissociation pathways that could also bias quantitation [13]. Calibration curves of the sn-specific product ions for PC 16:0/18:1 and PC 18:1/1...
What is the difference between fatty acid composition and sn-2?
Fatty acid composition (FA%, w/w) described individual fatty acid in total fatty acids, and sn -2 fatty acid composition ( sn -2 %, w/w) described a specific fatty acid at sn -2 position compared with the total amount of this fatty acid (relative percentage of each fatty acid in sn -2 position).
What is the role of SN-position in phospholipid-linked fatty acids?
sn-position determination of phospholipid-linked fatty acids derived from erythrocytes by liquid chromatography electrospray ionization ion-trap mass spectrometry The sn-position of FA in membrane lipids has an influence on the physiological function of cells, is predictive for diseases, and therefore is useful for diagnostics.
What does SN mean in glycerophospholipids?
In general, glycerophospholipids use a "sn" notation, which stands for stereospecific numbering. When the letters "sn" appear in the nomenclature, by convention the hydroxyl group of the second carbon of glycerol (2- sn) is on the left on a Fischer projection.