Is the hydrolysis of tert-butyl chloride an S N 2 reaction?
Although the hydrolysis of tert-butyl chloride, as shown above, might be interpreted as an S N 2 reaction in which the high and constant concentration of solvent water does not show up in the rate equation, there is good evidence this is not the case.
What factors affect the reaction rate of tert-butyl chloride?
The reaction rate can be affected by certain factors such as the addition of catalysts, concentration of reactants, physical states of reactants, and temperature such as in the reaction of the hydrolysis of tert-butyl chloride in this experiment. One method of studying chemical kinetics is by
What happens if the tert-butyl chloride solution is uncorked?
d. If the flask is uncorked while the tert-butyl chloride solution is being heated to complete the reaction, so that some of the tert-butyl chloride is lost by evaporation, this would affect the results we obtained for the rate constant. They would probably be precise but not accurate.
What are the characteristics of chiral 3o-alkyl bromide reaction?
It not only shows first order kinetics, but the chiral 3º-alkyl bromide reactant undergoes substitution by the modest nucleophile water with extensive racemization. In all of these features this reaction fails to meet the characteristics of the S N 2 mechanism. A similar example is found in the hydrolysis of tert-butyl chloride, shown below.
A SN1 Reaction: Synthesis of tert-Butyl Chloride