What are the different types of local anesthesia?
Spinal anesthesia, used for doing cesarean section, is also a type of nerve block. Two kinds of local anesthetic drugs are used nowadays. The commonly used drugs are amides like lignocaine, prilocaine, and bupivacaine. The other group is esters like cocaine, procaine, and amethocaine. How Long Does Local Anesthesia Last?
What are local anesthetic drugs used for?
Local anesthetic drugs are injected near nerves to block the pain from the area supplied by the nerve. Your doctor uses nerve blocks for dental treatment and eye operations. Spinal anesthesia, used for doing cesarean section, is also a type of nerve block. Two kinds of local anesthetic drugs are used nowadays.
What is the basic structure of a local anesthetic molecule?
Chemistry The basic chemical structure of a local anesthetic molecule consists of 3 parts: 1. Lipophilic group- an aromatic group, usually an unsaturated benzene ring. 2. Intermediate bond- a hydrocarbon connecting chain, either an ester (-CO-) or amide (-HNC-) linkage.
Are local anesthetics stereospecific?
Local anesthetics are stereospecific. Their action is dependent on the conformational state of the Na+ channel. Local anesthetics ability to bind to sodium channels is known as a state-dependent block”. Local anesthetics bind more readily to the Na+ channel during depolarization (when it is open or activated).