Why this Chapter? ▫ Much of organic chemistry involves the chemistry of carbonyl compounds ▫ Aldehydes/ketones are intermediates in
Chapter . Aldehydes and Ketones Nucleophilic Addition Reactions
Chapter 17: Aldehydes and Ketones: Nucleophilic Addition to the Carbonyl Group 17 1: Nomenclature (please read) suffix: –al for aldehydes –one for ketone
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3 oct 2010 · Strong Nucleophiles tend to react irreversibly Weak Lewis Bases/Nucleophiles require protonation of the aldehyde/ketone, just like an epoxide: Protonation of aldehydes/ketones makes them stronger Lewis Acids/Electrophiles that can then react with weak nucleophiles such as water, alcohols etc , just like epoxides
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nucleophilic addition to carbonyl compounds; however, other nucleophiles can undergo the same reaction • There are other acid- and base-catalyzed examples
DB Carbonylnotes
The addition of carbon nucleophiles into aldehydes and ketones provides one of the most effective ways of forming new C−C bonds, as well as alcohols Many
lecture (student HO)
Nucleophilic Addition Reactions McMurry Aldehydes/ketones are intermediates in synthesis of Carbonyl compounds are planar about the double bond and
1 Chapter 9 Aldehydes and Ketones: Nucleophilic Addition Reactions Carbonyl group, C=O: the most important and widely occurring functional group
Chapter Aldehydes and Ketones
The most characteristic reaction of aldehydes and ketones is nucleophilic addition to the carbon– oxygen double bond The nucleophile can be neutral or
sch aldehydes and ketones reactions
Oxidation of secondary alcohols yields ketones Aldehydes are very easily oxidized to carboxylic acids Nucleophific addition reactions to the carbon- oxygen
aldehydes ketones
Chapter 17: Aldehydes and Ketones: Nucleophilic Addition to the Carbonyl Group 17 1: Nomenclature (please read) suffix: –al for aldehydes –one for ketone
Oxidation of secondary alcohols yields ketones Aldehydes are very easily oxidized to carboxylic acids RCH2OH Aldehyde R
Aldehydes and Ketones 18 The general reaction pathways of Nucleophilic Addition Reactions of Aldehydes and Ketones leads to an alcohol product or
Carbonyl compounds (Aldehydes and ketones): Nucleophilic addition Electromeric effect Qualitative tests for Aldehydes and ketones
Aldehydes and Ketones: Nucleophilic Addition Reactions McMurry 'Fundamentals of Organic Chemistry' 7th Ed Chapter 9
The parent chain is numbered to give the ketone carbonyl the lowest possible ?Addition of a nucleophile to a carbonyl carbon occurs because of
For charged nucleophile H- R- NC- and others the nucleophilic addition takes place directly on the carbonyl as shown below We already have seen this
nucleophilic addition to carbonyl compounds; however other nucleophiles can undergo the same reaction • There are other acid- and base-catalyzed examples
[PDF] Aldehydes and Ketones: Nucleophilic Addition to the Carbonyl