What is Fipronil?
What is fipronil Fipronil is a broad use insecticide that belongs to the phenylpyrazole chemical family. Fipronil is used to control ants, beetles, cockroaches, fleas, ticks, termites, mole crickets, thrips, rootworms, weevils, and other insects. Fipronil is a white powder with a moldy odor.
Is Fipronil safe for weanlings?
Similarly, in trials with weanlings and juveniles, there were no significant adverse effects observed in this relatively vulnerable group and therefore fipronil could be considered safe to use in younger animals, including weanlings.
Why does fipronil have a high selectivity for invertebrate pests?
Glutamate-gated GABA chloride channels appear to be a critical target for fipronil (Zhao et al., 2004) and, since these channels are only found in invertebrates (Raymond and Sattelle, 2002), possibly explains the high selectivity of fipronil for invertebrate pests (Zhao et al., 2004).
Is Fipronil bioavailable in dogs and cats?
The bioavailability of topically-applied fipronil is generally accepted as 5% dogs and cats (Brayden, 2003) due to limited permeability through the stratum corneum (Birckel et al., 1996; Cochet et al., 1997). Limited information is available regarding transdermal movement of fipronil and/or metabolites through dogs and cats.