https://www.ema.europa.eu/en/documents/scientific-guideline/guideline-development-production-characterisation-and-specification-monoclonal-antibodies-and-related-products-revision-1_en.pdf
30 мая 2012 г. • Fc-associated functions (e.g. antibody-dependent cell-mediated cytotoxicity ADCC; ... Although each of the factors mentioned here do not ...
20 нояб. 2018 г. As demonstrated here this approach can be used to design biologically active antibodies
In some instances antibodies can modify the function of the antigen molecules toward which they are directed without being necessarily connected to the
5 окт. 2023 г. It has been widely assumed that these nonneutra- lizing antibodies do not function in a protective way in vivo and therefore are not desirable.
18 дек. 2020 г. These antibodies can bind and hydrolase pathogen-specific target molecules thus potentially contributing to the immune defence. Indeed
Influenza vaccination can also boost Fc-functional antibodies targeting divergent strains of influenza virus. Healthy adults immunized with a quadrivalent
since prior episodes of H influenzae do not confer immunity. By age 5 years most children have naturally acquired antibodies. The HIB conjugate vaccine
18 мая 2023 г. entists can make and use every functional antibody if they simply fol- low the “roadmap” or “conservative substitution.” These two ap ...
15 апр. 2023 г. In addition to neutralization antibodies can ... Specifically