Nitriles react with sodium perborate or copper salts to yield carboxylic acids under mild acidic conditions. The multiphase reaction can be carried out in
Conventional chemical conversion of nitriles suffers from several disadvantages including the requirement for highly acidic or basic reaction conditions
Herein we report that cyanohydrins generated by the reaction of cyanide with ?-keto acids and ?-keto-alcohols
highly active catalysts in nitrile hydrolysis under neutral conditions. The hydrolysis of nitriles to amides and carboxylic acids are very important.
Hydrolysis of carboxylic acid esters amides
unfavourable ecological consequences. Clearly the hydrolysis of nitriles to carboxylic acids at room temperature and under neutral conditions would be
requires rather strong acidic or basic conditions. Chemoselective hydrolysis of heterocyclic nitriles can be achieved by an easy to use immobilized bio-.
The hydrolysis of nitriles is a method frequently used for hydration of nitriles apply usually strong acidic conditions espe-.
Hydrolysis of nitriles resembles the hydrolysis of amides. In basic solution the carboxylic acid product ... under the reaction conditions.
fungi. One pathway involves the sequential hydrolysis of the nitrile molecule to its corresponding carboxylic acid via an amide intermediate. This reaction.
Dry hydrolysis of nitriles by sodium perborate and copper salts in