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Functional antagonism: 2 chemicals counterbalance each other by producing opposite effects on the same physiologic function (eg epinephrine + diazepam) •
Agonist A drug that binds to receptor and has a cellular (pharmacological) effect Antagonist A drug that binds to a receptor but produces no direct
For example, toxic agents may be chemical (such as cyanide), physical (such as radiation) and biological (such as snake venom) A distinction is made for
on health and the environment, for example in relation to air quality, Interactions (including antagonism, potentiation, and synergies) usually occur at
Toxicology is the study of the adverse effects of chemical, biological, or physical agents on For example, the receptor antagonist naloxone treats the
The Toxicological Effects of Exposure to Mixtures of Industrial and Environmental Chemicals Examples of interaction of reproductive toxicants in vivo