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Immunology Review: GOOD LUCK ON THE FINAL EXAM Our major focus is the adaptive immune system – types of cells that produce receptors (either antibodies or T-cell receptors) that will be able to recognize either parts of proteins, carbohydrates, lipids (in the case of Abs) or parts of proteins (in the case of T-cell receptors)
To ensure that results are reported timely to optimize patient care and patient outcomes To define the tests that can be ordered on a STAT basis and the interval of time between when the sample is received in the laboratory and the results are reported _____
TRANSPLANTATION IMMUNOLOGY 124 Terminology 124 Graft rejection and survival 125 Stem cell transplantation 126 Graft versus host disease (GVHD) 126 Xenotransplantation 127 TUMOUR IMMUNOLOGY 127 Tumour-associated antigen 127 Tumours of the immune system 128 IMMUNOLOGICAL ASSAYS 129 1 Agglutination assays 129 Coombs’ antiglobulin test 129 2
At Clinipath Pathology, the test is performed by immunofluorescence, and a titre is given, as well as the pattern of the fluorescence The ANA may represent many autoantibodies, so once an ANA is found, often further testing needs to be done to elucidate the type of antibody Titre The titre is determined by the lowest
Interpreting Total IgE with Speci˜c IgE Test Results (Above age 15)* Speci˜c IgE Undetectable <0 10 KU/L Symptoms not attributed to atopy Does not rule out atopy if Speci˜c IgEs are elevated3 May indicate high risk of sensitization; may be useful to decide if further investigation warranted3 Total IgE Normal <101 IU/mL Total IgE Elevated
Individual Readiness Assurance Test 5-10 minutes Group Readiness Assurance Test 5-10 minutes Group Activity Exercise 10-30 minutes Faculty-Led Class Discussion 5-10 minutes In our graduate-level immunology course entitled “Principles of Immunology”, TBL constituted 25 of