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IMMUNOLOGYAnOfficialJournaloftheBritishSocietyforImmunologyVOL29NO1JULY1975CONTENTSD.E.S.STEWART-TULL,T.SnwoNo,S.KOTANI,M.KATO,Y.OGAWA,Y.YAMAmuRA,T.KOGAandC.M.PEARSON:Theadjuvantactivityofanon-toxic,water-solubleglycopeptidepresentinlargequantitiesintheculturefiltrateofMycobacterinumtuberculosisstrainDTIJ.V.CHUBA,W.J.KuHNs,J.D.OPPENHEIM,M.S.NACHBARandR.F.NIGRELLI:Multiplespecificitiesofmammalianbloodgroupsubstancescomparativelystudiedwithhumanisoagglutininsandfractionatedanti-Hlectins17E.D.STEEL:AdsorptioninvitrotoEscherichiacoliofantibodiesandotherproteinsinbovineserumandcolo-strumanditseffectsontheproductionofE.coliagglutinins31G.F.MITCHELL:Promotionofsecondaryanti-DNPantibodyproductioninmicebytypeIIIpneumococcalpolysaccharide(SIII)anddinitrophenylatedrabbitantibodytoSIII39R.M.CoLEMAN,N.J.RENcluccA,J.P.STOUT,W.H.BRIsSETrEandD.M.SmrrH:Splenicmediatederythrocytecytotoxicityinmalaria49K.J.TURNER,R.HAcrsjuw,J.PAP^DnumRrou,.J.D.WETHERALLandJ.PfRRorr:Experimentalasper-gillosisinratsinfectedviaintraperitonealandsubcutaneousroutes55C.S.F.EASMONandA.A.GLrNN:Theroleofhumoralimmunityandacuteinflammationinprotectionagainststaphylococcaldermonecrosis67C.S.F.EASMONandA.A.GLYNN:Cell-mediatedimmuneresponsesinStaphylococcusaureusinfectionsinmice75KATHRYNK.NuDoRa,S.ScHLEcHT,E.RUDEand0.WESTPHAL:ImmunologicalresponsestoSalmonellaRantigens.ThebacterialcellandtheproteinedestinascarriersforRoligosaccharidedeterminants87M.RiCHTmR,HELENECOLASDELANoUnandH.HAuDY:Cellsinvolvedintheimmuneresponse.XXVIII.Thecellularcompositionofthelymphoidorgansinthenormaloutbredrabbit103B.J.BRYANT,M.W.HEssandH.COTTIER:Thymuslymphocytes.Effluxandrestorationphasesafterperipheralexposureofmicetophytohaemagglutinin115Y.KATAOKAandT.SADo:TheradiosensitivityofTandBlymphocytesinmice121FELucrryA.CmuIsANandJ.L.GORDON:PlateletfunctioninC6-deficientrabbits.Aggregationandsecretioninducedbycollagenandzymosan131R.V.HEATLEYandJ.M.STARK:Immunogenicityoflipid-conjugatedproteinintheintestine143ANNIPaouvosr-DANoN,JANINAWYCZoLRowsKA,R.BINAGHIandANNEABADmE:MouseandratIgE.Cross-sensitizationofmastcellsandantigenicrelationships151E.J.GOETZL:Modulationofhumanneutrophilpolymorphonuclearleucocytemigrationbyhumanplasmaalpha-globulininhibitorsandsyntheticesteraseinhibitors163DENIsEBuFrandCmIsTIANERnmAur:Immunosuppressiveeffectofahumanhepaticglycoferroprotein,a2Hglobulin.Astudyonthetransformationofnormalhumanlymphocytes157R.J.HEDDLEandD.RowLEY:Dogimmunoglobulins.I.Immunochemicalcharacterizationofdogserum,parotidsaliva,colostrum,milkandsmallbowelfluid185R.J.HEDDLEandD.RowLEY:Dogimmunoglobulins.II.TheantibacterialpropertiesofdogIgA,IgMandIgGantibodiestoVibriocholerae197ANmcToURNEFIER:Incompleteantibodiesandimmunoglobulincharacterizationinadulturodeles,PleurodeleswaltliiMichah.andTriturusalpestrisLaur.209BOOKREvinws219ANNOUNCEMENTS222BLACKWELLSCIENTIFICPUBLICATIONSOXFORDLONDONEDINBURGHMELBOURNEPrintedinGreatBritainattheAldenPress,Oxford.

rIniversftfAiIS107429LIBRARYforMedicalSc;^/r1TapCONTENTSVol.29No.1July1975D.E.S.STEWART-TULL,T.SHIMONO,S.KOTANI,M.KATO,Y.OGAWA,Y.YAMAMURA,T.KOGAandC.M.PEARSON:Theadjuvantactivityofanon-toxic,water-solubleglycopeptidepresentinlargequantitiesintheculturefiltrateofMycobacteriumtuberculosisstrainDT1J.V.CHUBA,W.J.KUHNS,J.D.OPPENHEIM,M.S.NACHBARandR.F.NIGRELLI:Multiplespecificitiesofmammalianbloodgroupsubstancescomparativelystudiedwithhumanisoagglutininsandfractionatedanti-Hlectins17E.D.STEEL:AdsorptioninvitrotoEscherichiacoliofantibodiesandotherproteinsinbovineserumandcolostrumanditseffectsontheproductionofE.coliagglu-tinins31G.F.MITCHELL:Promotionofsecondaryanti-DNPantibodyproductioninmicebytypeIIIpneumococcalpolysaccharide(SIII)anddinitrophenylatedrabbitantibodytoSIIIR.M.COLEMAN,N.J.RENCRICCA,J.P.STOUT,W.H.BRISSETTEandD.M.SMITH:Splenicmediatederythrocytecytotoxicityinmalaria49K.J.TURNER,R.HACKSHAW,J.PAPADIMITRIOU,J.D.WETHERALLandJ.PERROTT:Experimentalaspergillosisinratsinfectedviaintraperitonealandsubcutaneousroutes55C.S.F.EASMONandA.A.GLYNN:Theroleofhumoralimmunityandacutein-flammationinprotectionagainststaphylococcaldermonecrosis67C.S.F.EASMONandA.A.GLYNN:Cell-mediatedimmuneresponsesinStaphy-loccusaureusinfectionsinmice75KATHRYNK.NIXDORFF,S.SCHLECHT,E.RUDEand0.WESTPHAL:ImmunologicalresponsestoSalmonellaRantigens.ThebacterialcellandtheproteinedestinascarriersforRoligosaccharidedeterminants87M.RICHTER,HELENECOLASDELANougandH.HAMDY:Cellsinvolvedintheimmuneresponse.XXVIII.Thecellularcompositionofthelymphoidorgansinthenormaloutbredrabbit103B.J.BRYANT,M.W.HESSandH.COTTIER:Thymuslymphocytes.Effluxandrestorationphasesafterperipheralexposureofmicetophytohaemagglutinin115Y.KATAOKAandT.SADO:TheradiosensitivityofTandBlymphocytesinmice121FELICITYA.CHRISTIANandJ.L.GORDON:PlateletfunctioninC6-deficientrabbits.Aggregationandsecretioninducedbycollagenandzymosan131R.V.HEATLEYandJ.M.STARK:Immunogenicityoflipid-conjugatedproteinintheintestine143ANNIEPROUVOST-DANON,JANINAWYCZOLKOWSKA,R.BINAGHIandANNIEABADIE:MouseandratIgE.Cross-sensitizationofmastcellsandantigenicrelationships151iii

E.J.GOETZL:Modulationofhumanneutrophilpolymorphonuclearleucocytemi-grationbyhumanplasmaalpha-globulininhibitorsandsyntheticesterasein-hibitors163DENISEBUFFEandCHRISTIANERIMBAUT:Immunosuppressiveeffectofahumanhepaticglycoferroprotein,a2Hglobulin.Astudyonthetransformationofnormalhumanlymphocytes157R.J.HEDDLEandD.ROWLEY:Dogimmunoglobulins.I.Immunochemicalcharac-terizationofdogserum,parotidsaliva,colostrum,milkandsmallbowelfluid185R.J.HEDDLEandD.ROWLEY:Dogimmunoglobulins.II.TheantibacterialpropertiesofdogIgA,IgMandIgGantibodiestoVibriocholerac197ANNICKTOURNEFIER:Incompleteantibodiesandimmunoglobulincharacterizationinadulturodeles,PleurodeleswalthiiMichah.andTriturusalpestrisLaur.209BOOKREVIEWS219ANNOUNCEMENTS222Vol.29No.2August1975R.H.WEISBART,JUDITHISAACSON,R.BLUESTONEandL.S.GOLDBERG:Humanpolymorphonuclearleucocytemigrationinhibitoryfactor.Evidenceforantigendependency223BOZENAHoCHOVA,J.KREJCI,J.PEKAREK,J.SVEJCARandJ.JOHANOVSKY:Furthercharacterizationofantigen-dependentmigrationinhibitionfactorinmice231D.S.GREGERSON,BARBARAKELLYandJULIAG.LEVY:Responsesofguinea-piglymphocytestomitogens,anantigen,andmixedleucocytecultureinmediawithandwithoutmerceptoethanolandfoetalcalfserum237JULIAG.LEVYandBARBARAKELLY:Cellularco-operationbymouselymphocytestochemicallydefinedantigens247R.S.LLOYDandD.R.TRIGER:Studiesonhepaticuptakeofantigen.III.Studiesoflivermacrophagefunctioninnormalratsandfollowingcarbontetrachlorideadministration253EDITHWIENERandA.BANDIERI:Modificationsinthehandlinginvitroofl2I-labelledKeyholelimpethaemocyaninbyperitonealmacrophagesfrommicepretreatedwiththeadjuvantCorynebacteriumparvum265T.L.VISCHERandJ.J.LOSPALLUTO:Thedifferentialeffectofcholeratoxinonthelymphocytestimulationinducedbyvariousmitogens275H.FRIEDMAN:VibriolyticIgGimmunocyteresponseofmiceafterprimaryandsecondaryimmunizationwithcholerasomaticantigens283A.LANTZandG.W.SISKIND:Studiesonthecontrolofantibodysynthesis.VIII.Selectionforhighaffinityantibodyproductioninthesecondaryresponse301H.MATSUDA,T.BABAandY.BITO:Thebursaloriginofanimmunocompetentcellforantibodyformationinthechicken3071.MOTAandA.PERINI:Theeffectofasyntheticdouble-strandedRNAonIgGlandIgEproductionbyguinea-pigs.Acomparativestudywithlipopolysac-charide319W.B.VANMUISWINKEL,J.J.VANBEEKandP.L.VANSOEST:TherecoveryoftheB-cellpopulationinadultthymectomized,lethallyirradiatedandbonemarrow-reconstitutedmice327iv

G.COHNEN,K.FISCHERandG.BRITTINGER:HumanT-lymphocyterosetteformation.InhibitionbycytochalasinB337R.J.SIMES,R.KEARNEYandD.S.NELSON:Roleofanon-committedaccessorycellintheinvivosuppressionofasyngeneictumourbyimmunelymphocytes343P.M.COMOGLIO,MARILENABERTINIandG.FORNI:Evidenceforamembranecarriermoleculecommontoembryonalandtumour-specificantigenicdeter-minantsexpressedbyamousetransplantabletumour353P.N.SHEKandS.DUBISKI:Maternal-foetaltransferofnormalIgMintherabbit365M.K.BACHandJ.R.BRASHLER:InhibitionofIgEandcompound48/80-inducedhistaminereleasebylectins371ANNEPERRUDET-BADoux,R.A.BINAGHIandG.Biozzi:Trichinellainfestationinmicegeneticallyselectedforhighandlowantibodyproduction387D.J.PEARSONandG.TAYLOR:TheinfluenceofthenematodeSyphaciaoblevataonadjuvantarthritisintherat391G.H.MITCHELL,G.A.BUTCHERandS.COHEN:MerozoitevaccinationagainstPlasmodiumknowlesimalaria397Vol.29No.3September1975R.TANENBAUMandD.SULITZEANU:Enrichmentofmemorycellscarryingreceptorsforaproteinantigen(HSA).II.Improvedenrichmenttechnique,usingBSAdensitygradientseparation409JEANNINECHARREIRE,A.FAUREandJ.-F.BACH:StudiesonB-andT-cellreceptorsforlysozyme423NABILHANNA,RINAKALDERONandD.NELKEN:InhibitionofT-andB-lympho-cytefunctionsbynormalimmunosuppressiveprotein433J.CLOT,HELENEMASSIPandO.'MATHIEU:InvitrostudiesonhumanBandTcellpurifiedpopulations.Stimulationbymitogensandallogeneiccells,andquantitativebindingofphytomitogens445M.VOLKERT,K.BRO-J0RGENSEN,0.MARKER,B.RUBINandLOTTETRIER:TheactivityofTandBlymphocytesinimmunityandtolerancetothelymphocyticchoriomeningitisvirusinmice455W.PIERPAOLI:Inabilityofthymuscellsfromnewborndonorstorestoretrans-plantationimmunityinathymicmice465G.HARRIS:Thelabellingofperipheralbloodlymphocytesofthemousewith[3H]thymidine469S.MARSHALL-CLARKEandJ.H.L.PLAYFAIR:Age-dependentchangesintherelativeaffinityofanti-dinitrophenylantibodiesinmice477S.AHLSTEDTandJ.HOLMGREN:AlterationoftheantibodyresponsetoEscherichiacoli0antigeninmicebypriorexposuretovarioussomaticantigens487B.D.JANKOVIC,KATARINAISAKOVId,M.L.LuKIC,N.L.VUJANovIc,SPOMENKAPETROVICandB.M.MARKOVIC:Immunologicalcapacityofthechickenembryo.I.Relationshipbetweenthematurationoflymphoidtissuesandtheoccurrenceofcell-mediatedimmunityinthedevelopingchickenembryo497TINHAN:Humanchorionicgonadotropin.Itsinhibitoryeffectoncell-mediatedimmunityinvivoandinvitro509R*v

G.SOMMER,DARIENPARKERandJ.L.TURK:Epicutaneousinductionofhyporeac-tivityincontactsensitization.Demonstrationofsuppressorcellsinducedbycontactwith2,4-dinitrothiocyanatebenzeneM.K.CHURCH:CorrelationofanaphylacticbronchoconstrictionwithcirculatingreaginicantibodylevelandactivecutaneousanaphylaxisintheratR.D.BARNES,MAUREENTUFFREY,PAMELALUND,LINDADAWSON,JEANHOLLIDAY,T.D.KINGandD.CATTY:InvestigationofNZBmiceborntoBALB/cimmunizedagainstNZBallotypeF.E.KATZandM.W.STEWARD:ThegeneticcontrolofantibodyaffinityinmiceR.BURGER,U.HADDING,H.U.SCHORLEMMER,V.BRADEandD.BITTER-SUER-MAN:Dextransulphate:asyntheticactivatorofC3viathealternativepath-way.I.InfluenceofmolecularsizeanddegreeofsulphationontheactivationpotencyP.KINNAERT,AGNESMAHIEU,NANCYVANGEERTRUYDEN,RENEED'ORCHIMONTandR.GoOSSENS:OrgandistributionofsheepredbloodcellsinALS-treatedratsP.BRANDTZAEG:HumansecretoryimmunoglobulinM.AnimmunochemicalandimmunohistochemicalstudyJ.STEENSGAARD,H.K.W.JOHANSENandN.P.H.M0LLER:ComputersimulationofimmunochemicalinteractionsBOOKREVIEWSANNOUNCEMENTS517527535543549555559571581584Vol.29No.4October1975J.G.HOWARD,G.VICARIandBARBARAM.COURTENAY:Influenceofmolecularstructureonthetolerogenicityofbacterialdextrans.I.The1-6-linkedepitopeofdextranB512585J.G.HOWARDandBARBARAM.COURTENAY:Influenceofmolecularstructureonthetolerogenicityofbacterialdextrans.II.Theal-3-linkedepitopeofdextranB1355599J.G.HOWARD,BARBARAM.COURTENAYandG.VICARI.Influenceofmolecularstructureonthetolerogenicityofbacterialdextrans.III.Dissociationbetweentoleranceandimmunitytotheal-6-andal-3-linkedepitopesofdextranB1355611H.NOWACK,E.HAHNandR.TIMPL:SpecificityoftheantibodyresponseininbredmicetobovinetypeIandtypeIIcollagen621E.A.GOIDL,J.J.BARONDEssandG.W.SISKIND:Studiesonthecontrolofantibodysynthesis.VII.Changeinaffinityofdirectandindirectplaque-formingcellswithtimeafterimmunizationinthemouse:lossofhighaffinityplaqueslateafterimmunization629I.NAKASHIMAandN.KATO:Amplificationofcell-associatedimmunologicalmemorybysecondaryantigenicstimulus.Secondarytypeincreaseinmemory643J.COUDERC,C.BLEUX,J.L.BIRRIENandP.LIACOPOULOS:Thepotentialityofantibody-producingcells.I.Bispecificcelloccurrenceindoublestimulatedculturesofsyngeneicorallogeneicspleencellsofthemouse653vi

J.COUDERC,C.BLEUXandP.LIACOPOULOS:Thepotentialityofantibody-producingcells.II.EvidencefortwoantibodymoleculesofdifferentspecificitiessecretedbymicromanipulatedbispecificmousespleencellsH.SNIPPEandELBARTEKAMP:Cellco-operationandhapten-carriercomplexesG.HARRIS,I.OLSENandP.MARRIOTT:DNAsynthesisinrabbitspleenexplants.ItsrelationshiptocelldivisionG.TUFVESONandG.V.ALM:EffectsofmitogensformouseBlymphocytesonchickenlymphoidcellsM.KALINAandNURITHHOLLANDER:TheeffectofcytochalasinBoneffector-targetcellinteraction.QuantitativeandultrastructuralstudyA.H.GREENBERG,L.SHENandG.MEDLEY:Characteristicsoftheeffectorcellsmediatingcytotoxicityagainstantibody-coatedtargetcells.I.Phagocyticandnon-phagocyticeffectorcellactivityagainsterythrocyteandtumourtargetcellsina5"Crreleasecytotoxicityassayand['25I]IUdRgrowthinhibitionassayR.J.SCHEPERandANSC.H.M.VANDINTHER-JANSSEN:Non-specificandDNP-erythrocyterosetteformationaftercontactsensitizationwithDNCBJ.ROVENSKY',J.DOSKO6IL,J.PEKAREK,L.BORECKY',D.ZITNANandJ.SVEJCAR:PreventionofspontaneousautoimmunitytoDNAinNZB/Swissmicebytreatmentwithnaturaldouble-strandedRNAP.J.COLEandM.E.MOLYNEUX:LymphocytereactivitytoinfluenzavirusinmanF.S.FARAH,S.A.SAMRAandN.NUWAYRI-SALTI:TheroleofthemacrophageincutaneousleishmaniasisC.R.BARKER,C.P.WORMANandJ.L.SMITH:PurificationandquantificationofTandBlymphocytesbyanaffinitymethodN.WELIKY,D.H.LEAMAN,JRandB.J.KALLMAN:Purificationofsolublecomple-ment-fixingantigensfromtwoBurkitt'slymphomacelllines.ConditionsaffectingthestabilityandrecoveryofantigensandantibodiesL.W.CLEMandW.E.McLEAN:Phylogenyofimmunoglobulinstructureandfunction.VII.Monomericandtetramericimmunoglobulinsofthemargate,amarineteleostfishBOOKREVIEWS665675687697709719731745749755765779791801Vol.29No.5November1975R.KURTHandGAYMEDLEY:Amembranepermeabilitytestforthedetectionofcellsurfaceantigens803J.P.DESSAINT,D.BOUT,P.WATTREandA.CAPRON:QuantitativedeterminationofspecificIgEantibodiestoEchinococcusgranulosusandIgElevelsinserafrompatientswithhydatiddisease813ALISONSLOWEandH.WALDMANN:The'intrinsicadjuvanticity'andimmuno-genicityoftrinitrophenylatedlipopolysaccharide825W.G.HARRIS:TheallergensofSchistosomamansoni.II.FurtherseparationbySephadexG-200andion-exchangechromatography835A.J.MUSSKE,J.F.WILLIAMS,R.W.LEIDandCHRISTINES.F.WILLIAMS:TheimmunologicalresponseoftherattoinfectionwithTaeniataeniaeformis.IV.Immunoglobulinsinvolvedinpassivetransferofresistancefrommothertooffspring845vii

A.J.MUSOKEandJ.F.WILLIAMS:ImmunologicalresponseoftherattoinfectionwithTaeniataeniaeformis.V.Sequenceofappearanceofprotectiveimmuno-globulinsandthemechanismofactionof7Sy2aantibodiesW.J.HOPKINS:Anti-thymocyteserummayenhanceorsuppresstheresponsetothesameantigenicdeterminantH.TOKUYAMA:InvitroproliferativeresponseofBALB/cmousespleencellsstimu-latedwithtrinitrophenylatedsyngeneicspleencellsLEACERCEK,P.MILENKOVIC,B.CERCEKandL.G.LAJTHA:InductionofPHAresponseinmousebonemarrowcellsbythymicextractsasstudiedbychangesinthestructurednessofcytoplasmicmatrixR.JENKINS:Distributionofelectrophoreticmobilitiesofmousethymocytesub-populationsinthepresenceoftumourcellsA.ARNAIZ-VILLENA,B.JONESandI.M.ROITT:Allograftcytotoxicity.RoleofTlymphocytesbearingareceptorforcomplementR.J.SCHEPER,J.P.A.BAAK,S.HiISIVARAandR.W.VELDHUIZEN:RRBCandEACrosetteformationafterDNCBcontactsensitizationandcyclophosphamidetreatmentofguinea-pigsI.M.HUNNEYBALLandD.R.STANWORTH:FragmentationofhumanIgGbyanewproteaseisolatedfromthebasidiomyceteArmillariamelleaJ.-P.VAERMAN,MICHELEC.NACCACHE-CORBICandJ.F.HEREMANS:Secretorycomponentoftheguinea-pigBRIEFCOMMUNICATIONJ.R.L.PINK,M.-P.McNALLYandJ.-C.JATON:ParaproteinaemiaininbredchickensBOOKREVIEWS855867875885893903909921933945951Vol.29No.6December1975F.L.SHAND:Analysisofimmunosuppressiongeneratedbythegraft-versus-hostreaction.I.AsuppressorT-cellcomponentstudiedinvivo953K.PFIZENMAIER,H.TROSTMANN,M.ROLLINGHOFFandH.WAGNER:Cell-mediatedallograftresponsesinvitro.VI.Studiesonmacrophage-mediatedcytotoxicity967LESLEYA.RADOv,D.H.SUSSDORFandR.L.MCCANN:Relationshipbetweenageofallogeneicthymusdonorandimmunologicalrestorationofathymic('nude')mice977R.B.TAYLOR:Apropositiononthedistributionofantibodyaffinities,withimplicationsforthemechanismofB-cellactivation989P.G.CUNNINGTONandJ.D.NAYSMITH:Naturallyoccurringdouble-strandedRNAandimmuneresponses.III.Immunogenicityandantigenicityinanimals1001A.J.HUSBANDandG.H.McDOWELL:Localandsystemicimmuneresponsesfollowingoralimmunizationoffoetallambs1019R.A.SCHLEGEL,J.M.FIDLER,MAUREENHOWARDandK.SHORTMAN:Antigen-initiatedB-lymphocytedifferentiation.VII.QuantificationofAFCprogenitorlevelsinadoptiveandcultureresponsestoNIP-POLantigen1029L.A.RoZENSZAJN,D.SHOHAMandI.KALECHMAN:ClonalproliferationofPHA-stimulatedhumanlymphocytesinsoftagarculture1041G.L.ASHERSON,P.J.WOODandBARBARAMAYHEW:Controloftheimmuneresponse.I.DepressionofDNAsynthesisbyimmunelymphnodecells1057viii

J.W.SMITH,MARTHAJANEADKINsandDEEMCCREARY:Localimmuneresponseinexperimentalpyelonephritisintherabbit.I.Morphologicalandfunctionalfeaturesofthelymphocyticinfiltrate1067J.W.SMITH:Localimmuneresponseinexperimentalpyelonephritisintherabbit.II.Lymphocytestimulationbylipopolysaccharideofinfectingorganism1077T.DIAMANTSTEINandE.BLITSTEIN-WILLINGER:Relationshipbetweenbiologicalactivitiesofpolymers.I.Immunogenicity,C3activation,mitogenicityforBcellsandadjuvantproperties1087M.TORTEN,R.C.JOHNSON,S.KAATTARI,CHERRYLEUNGandE.BENJAMINI:Immuneplasma-dependentcytotoxicityofimmuneandnon-immuneperi-pherallymphoidcellsfortargetcellscoatedwithbacterialouterunitmem-brane1093A.ARNAIZ-VILLENAandP.SHELDON:AutoimmuneNewZealandmouse.Altera-tionsinC3receptors,complement-inducedclumpsandfollicularadherenceofimmunecomplexes1103S.DIsSANAYAKEandF.C.HAY:InvestigationofthebindingsiteofmouseIgGsubclassestohomologousperitonealmacrophages1111K.NAKAMURO,N.TANIGAKIandD.PRESSMAN:CommonantigenicstructuresofHL-Aantigens.VI.Commonantigenicdeterminantslocatedonthe33,000-Daltonalloantigenicfragmentportionofpapain-solubilizedHL-Amolecules1119T.LIEU,G.CHAPMAN,M.S.DOSCHER,C.A.MIKORYAK,R.K.BROWNandY.M.KONG:Multipleantigenicsitesonaneicosapeptide.I.Precipitinstudiesinthegoat1133P.J.NEVEUandA.G.BORDUAS:Haptenandcarrierspecificitiesofcellularandhumoralresponsestohighlysubstituteddinitrophenyl-humangamma-globulinsinguinea-pigs1145G.E.CHISM,M.E.WOEHLERandR.E.LOVINS:N-Bromosuccinimideoxidationofanti-DNPandanti-DNP-p-aminobenzoylglutamateantibodiesinthepresenceandabsenceofprotectinghapten1153B.A.BALDOandG.UHLENBRUCK:Anti-galactanactivityinTridacnamaxima(Rbding)haemolymph.Calciumdependenceofthehaemagglutininsandpre-cipitins1161M.FUJIWARAandSHIGEKOFUJIWARA:Mechanismofterminationofimmunolo-gicaltolerance1171R.R.AVTALIONandR.SHAHRABANI:Studiesonphagocytosisinfish.I.InvitrouptakeandkillingoflivingStaphylococcusaureusbyperipheralleucocytesofcarp(Cyprinuscarpio)1181BOOKREVIEWS1189ANNOUNCEMENTS1192AUTHORANDSUBJECTINDEXESTOVOLUME291193ix