[PDF] Antioxidants and Regulation of Antioxidant Enzymes by Cellular

14534_351129030.pdf Antioxidants and Regulation of Antioxidant Enzymes by Cellular

Redox Status

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Corresponding Author

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Abstract

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Key words:

INTRODUCTION

Low Molecular Weight Radical

Scavengers (Non-enzymatic Antioxidants)

Antioxidant macromolecules are the

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G. Sadi ve Ö. Sadi / Journal Reviews, 3(2): 95-107, 2010 and aqueous phase at the expense of lipoic acid

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complexes and maintains the concentrations present at the central positions in the antioxidant can reduce all these antioxidants at the expense

Antioxidant Enzymes

Superoxide Dismutases (E.C:1.15.1.1)

-

Catalase (E.C: 1.11.1.6)

G. Sadi ve Ö. Sadi / Journal Reviews, 3(2): 95-107, 2010

Enzymes Working in Glutathione Redox

Cycle

Glutathione Peroxidase (E.C: 1.11.1.9)

in oxidized lipoproteins and peroxidized

Glutathione-S-Transferases (E.C:2.5.1.18)

in addition to selenium dependent neutralization leads to production of different isoforms of GST

Glutathione Reductase (E.C:1.6.4.2)

+ ĺ + G. Sadi ve Ö. Sadi / Journal Reviews, 3(2): 95-107, 2010 are are

Redox regulation of gene transcription

ț ț ț it to enter nucleus and initiate transcriptional

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Kinases and phosphatases in redox signal

transduction found to modulate the intracellular protein G. Sadi ve Ö. Sadi / Journal Reviews, 3(2): 95-107, 2010 reductants and antioxidants restore the oxidized

Antioxidant Response Elements

is essential for the coordinated induction of free to accumulate in nucleus and hence induce some antioxidants such as lipoic acid or G. Sadi ve Ö. Sadi / Journal Reviews, 3(2): 95-107, 2010 ț ț

REFERENCES

G. Sadi ve Ö. Sadi / Journal Reviews, 3(2): 95-107, 2010 Allen ț ț ț G. Sadi ve Ö. Sadi / Journal Reviews, 3(2): 95-107, 2010 effects of thioredoxin and antioxidants on G. Sadi ve Ö. Sadi / Journal Reviews, 3(2): 95-107, 2010

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G. Sadi ve Ö. Sadi / Journal Reviews, 3(2): 95-107, 2010

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G. Sadi ve Ö. Sadi / Journal Reviews, 3(2): 95-107, 2010

Figure 6. ț

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G. Sadi ve Ö. Sadi / Journal Reviews, 3(2): 95-107, 2010

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