A basic understanding of any of the programming languages will help you in understanding the Assembly programming concepts and move fast on the learning track
16 fév 2019 · This information is for the programmer who is coding in assembler language, and who needs to become familiar with the operating system and
29 mai 2019 · programs in assembler language or high-level languages, The SWA contains information about jobs that are currently in the system
5 août 2009 · This chapter presents a discussion of JCL (Job Control Language) as used for jobs run on a modern IBM mainframe running a descendant of the
6 fév 2009 · One of the main issues in learning Assembler Language for the IBM Mainframe Series, such as Purging Jobs from the Hold Queue
A program to break down the operands of an assembler language instruction into its constituent that runs the machine between jobs
As he developed his career, the technical aspects of programming were merely a means to He then learned assembly language and machine code on DEC PDP-11
Assembly language is almost certainly the most difficult kind of computer locomotive-sized nuggets every day (or even every century) most jobs a
options and IPOs, all make up the many reasons why a career in languages in use, and they all serve unique purposes, at General Assembly or our
Theȱebbȱandȱflowȱwithinȱtheȱtechnologyȱsector,ȱrangingȱfromȱtheȱdotȱcomȱbubbleȱtoȱoutsourcing,ȱhasȱprogrammersȱsearchingȱ
forȱjobȱsecurity.ȱȱManyȱindividualsȱhaveȱconsideredȱbecomingȱaȱSASȱprogrammerȱwithinȱtheȱBiotechȱandȱPharmaceuticalȱ
industryȱdueȱtoȱtheȱlongerȱprojectȱlifeȱcycleȱofȱyearsȱratherȱthanȱmonths.ȱȱTheȱbestȱpathȱtoȱenterȱthisȱfieldȱcanȱbeȱelusive.ȱȱThereȱ
areȱchallengesȱespeciallyȱforȱthoseȱstartingȱoutȱsinceȱitȱrequiresȱthreeȱyearsȱofȱexperienceȱtoȱobtainȱthatȱfirstȱjob.ȱȱThisȱpaperȱ
distillsȱrealȱlifeȱstoriesȱfromȱSASȱprogrammersȱwithinȱtheȱBiotechȱandȱPharmaceuticalȱindustry.ȱȱItȱdescribesȱmanyȱdifferentȱ
pathsȱandȱsuggestsȱrecommendationsȱbasedȱuponȱtheseȱexperiences.ȱȱWhenȱstartingȱoutȱonȱaȱnewȱcareerȱpath,ȱsageȱ
adviceȱfromȱseasonedȱprofessionalsȱinȱtheȱfieldȱcanȱsaveȱaȱlotȱofȱtimeȱandȱenergy.ȱȱArmedȱwithȱtheȱknowledgeȱandȱsharedȱexperiencesȱ
fromȱtheȱstoriesȱtoldȱinȱthisȱpaper,ȱyouȱwillȱpropelȱyourselfȱintoȱaȱmoreȱchallengingȱandȱsuccessfulȱcareer.ȱ
ThereȱareȱmanyȱpathsȱthatȱindividualsȱtakeȱtoȱarriveȱatȱaȱcareerȱasȱaȱSASȱProgrammer.ȱȱSASȱisȱaȱprogrammingȱlanguageȱwhichȱ
requiresȱtheȱrigorsȱofȱaȱcomputerȱscientist.ȱȱHowever,ȱtoȱbecomeȱaȱclinicalȱtrialsȱanalystȱalsoȱrequiresȱaȱthoroughȱ
understandingȱandȱknowledgeȱofȱtheȱclinicalȱdataȱtoȱbeȱanalyzed.ȱȱTheȱcombinationȱofȱtheseȱdistinctȱskillsȱattractsȱpeopleȱfromȱ
diverseȱbackgrounds.ȱȱItȱisȱsurprisingȱtoȱfindȱsoȱmanyȱdifferentȱbackgroundsȱofȱindividualsȱwithȱdifferingȱtalentsȱandȱinterestsȱ
whoȱgravitateȱtowardsȱthisȱcareerȱpath.ȱȱLikeȱmanyȱotherȱcareerȱpathsȱdealingȱwithȱtechnology,ȱthingsȱchange.ȱȱTheȱ
dynamicȱaspectsȱofȱtheȱjobȱrequireȱprogrammersȱtoȱbecomeȱresourcefulȱandȱtoȱsurvive.ȱȱTheyȱthereforeȱmustȱreȬinventȱthemselvesȱ
continually.ȱȱTheȱcoreȱunderstandingȱofȱtheȱanalyticsȱbehindȱclinicalȱtrialsȱevolvesȱbutȱremainsȱcomparativelyȱstable.ȱȱOnceȱ
youȱmasterȱthisȱandȱtheȱaccompanyingȱprogrammingȱtechniques,ȱyouȱ haveȱaȱgoodȱfoundationȱforȱbecomingȱaȱsuccessfulȱClinicalȱTrialsȱProgrammer.ȱȱȱThereȱareȱmanyȱscenariosȱwhichȱyouȱcanȱtake.ȱȱTheȱfollowingȱdiagramȱdepictsȱthree.ȱȱThereȱareȱ
manyȱmoreȱandȱtheȱcombinationsȱofȱstepsȱcanȱleadȱtoȱaȱmyriadȱofȱgoodȱpaths.ȱ
ȱ 1 1 2ThisȱpaperȱevaluatesȱvariousȱdifferentȱpathsȱthatȱindividualsȱtookȱonȱtheirȱroadȱthroughȱclinicalȱSASȱprogramming.ȱȱThereȱisȱ
noȱoneȱcorrectȱpathȱbutȱratherȱaȱdiverseȱset.ȱȱThisȱdemonstratesȱtheȱuniqueȱcombinationȱofȱskillȱsetsȱneededȱtoȱthriveȱinȱthisȱ
environment.ȱȱThisȱpositionȱhasȱonlyȱrecentlyȱbeenȱestablishedȱsoȱmanyȱof
ȱtheȱindividualsȱwhoȱenteredȱthisȱfieldȱdidȱnotȱsetȱoutȱtoȱbecomeȱaȱclinicalȱSASȱprogrammer.ȱȱForȱmany,ȱtheȱjourneyȱwasȱunplannedȱandȱthereȱwereȱnoȱroadȱmaps.ȱȱTheyȱwereȱ
pioneersȱandȱnavigatedȱtheirȱcareerȱpathȱfollowingȱtheirȱintuitionȱandȱreliedȱonȱluck.ȱȱThereȱareȱmanyȱlessonsȱthatȱcanȱbeȱ
gainedȱfromȱtheseȱpioneers.ȱȱTheȱpathsȱwhichȱtheseȱpioneersȱpavedȱwillȱprovideȱaȱclearerȱvisionȱandȱsetȱofȱdirectionsȱforȱ
futureȱaspiringȱSASȱprogrammersȱwhoȱplanȱtoȱventureȱonȱtheȱsameȱroads.ȱȱȱȱȱ
ȱ ASSOCIATEȱDIRECTORȱOFȱBIOANALYSISȱȬȱDAVIDȱTAPPEȱ It is not about how good a SAS programmer you are. It is about being focused on the data and your representation of the data that leads to success. ȱWhenȱDavidȱstartedȱoutȱonȱhisȱfirstȱSASȱprogrammingȱpositionȱatȱSyntexȱinȱPaloȱAlto,ȱCaliforniaȱinȱtheȱ80s,ȱthisȱtypeȱofȱworkȱ
wasȱnotȱwellȱunderstoodȱnorȱwellȱknownȱonȱtheȱwestȱcoast.ȱȱTheȱtermȱȈBioanalystȈȱusedȱatȱSyntexȱforȱstatisticalȱprogrammersȱ
wasȱforeignȱandȱheȱdidȱ notȱknowȱwhatȱtoȱexpect.ȱȱȱDavidȱwentȱtoȱUCLAȱtoȱobtainȱhisȱbachelorsȱdegreeȱinȱMathematics.ȱȱHeȱthenȱcontinuedȱhisȱstudiesȱatȱFresnoȱStateȱinȱBiologyȱ
andȱdidȱhisȱthesisȱworkȱinȱLymnology,ȱorȱtheȱstudyȱofȱfreshȱwaterȱecosystems.ȱȱHisȱacademicȱexperienceȱdidȱnotȱincludeȱ
formalȱcomputerȱscienceȱnorȱteachȱhimȱhowȱtoȱprogramȱinȱSAS,ȱbutȱitȱdidȱincludeȱexposureȱtoȱresearchȱmethodsȱandȱstatisticsȱ
thatȱheȱusedȱinȱhisȱthesis.ȱȱInȱfact,ȱDavidȱhadȱlittleȱformalȱprogrammingȱtraining.ȱȱHeȱwasȱintroducedȱtoȱprogrammingȱwhenȱ
heȱtookȱaȱFORTRANȱcourseȱatȱUCLA.ȱȱBackȱinȱtheȱdaysȱofȱpunchȱcards,ȱ
heȱusedȱFORTRANȱforȱanȱecosystemȱmodelingȱclassȱinȱgraduateȱschool.ȱOutȱofȱpersonalȱinterest,ȱheȱlearnedȱBASICȱprogrammingȱonȱhisȱownȱwhileȱworkingȱasȱaȱLabȱTechnicianȱatȱ
U.C.ȱBerkeley.ȱȱAsȱheȱdevelopedȱhisȱcareer,ȱtheȱtechnicalȱaspectsȱofȱprogrammingȱwereȱmerelyȱaȱmeansȱtoȱanȱend.ȱȱThatȱendȱ
wasȱtheȱdataȱitselfȱandȱhowȱtheȱdataȱdemonstratedȱmeaningȱwhenȱanalyzed.ȱȱTheȱmeaningȱofȱtheȱdataȱwasȱthereforeȱpivotalȱ
andȱoverrodeȱtheȱmechanicsȱofȱgettingȱthere.ȱȱDavidȱgainedȱenoughȱproficiencyȱinȱprogrammingȱonȱtheȱjobȱtoȱperformȱwellȱinȱ
hisȱjobȱwithoutȱmuchȱformalȱtraining.ȱWalnutȱCreekȱinȱtheȱeastȱbayȱafterȱheȱhadȱcompletedȱhisȱcourseȱworkȱinȱFresno.ȱȱHeȱexploredȱjobsȱinȱ
theȱbayȱareaȱandȱfirstȱworkedȱinȱtheȱdepartmentȱofȱMaterialsȱScienceȱatȱU.C.ȱBerkeleyȱhelpingȱonȱresearchȱprojectsȱaimedȱatȱ
findingȱwaysȱtoȱutilizeȱcoalȱdust.ȱȱAsȱthatȱjobȱwasȱending,ȱheȱfoundȱaȱjobȱannouncementȱatȱtheȱU.C.ȱBerkeleyȱplacementȱcenterȱ
forȱaȱBioanlystȱatȱSyntex.ȱȱSyntexȱwasȱanȱestablishedȱpharmaceuticalȱcompany,ȱbutȱdueȱtoȱtheȱlackȱofȱexperiencedȱstatisticalȱ
programmersȱinȱtheȱbayȱareaȱatȱtheȱtime,ȱtheyȱhiredȱpeopleȱatȱentryȱlevel.ȱȱAlthoughȱheȱlackedȱtheȱjobȱspecificȱ
experience,ȱheȱappliedȱforȱtheȱjobȱatȱSyntexȱbecauseȱheȱwasȱintriguedȱbyȱtheȱblendȱofȱstatistics,ȱhealthȱresearchȱandȱprogrammingȱmentionedȱ
inȱtheȱjobȱannouncement.ȱȱAtȱtheȱtime,ȱhowever,ȱheȱdidȱnotȱknowȱwhatȱaȱBioanalystȱdidȱorȱwhatȱtheȱjobȱentailed.ȱȱTheȱ
commuteȱfromȱWalnutȱCreekȱtoȱPaloȱAltoȱrequiredȱhimȱtoȱgoȱoverȱtheȱeastȱbayȱhills,ȱacrossȱoneȱofȱtheȱbayȱbridges.ȱȱThisȱaddedȱ
toȱhisȱcommuteȱtotalingȱaboutȱ60ȱmiles.ȱȱTheȱjobȱhadȱtoȱproveȱtoȱbeȱaȱgoodȱfitȱforȱhimȱtoȱkeepȱupȱwithȱthisȱgruelingȱcommute,ȱ
evenȱwithȱtheȱhelpȱofȱaȱcarpool.ȱȱInȱtheȱend,ȱitȱwasȱtheȱresearchȱaspectȱandȱabilityȱtoȱunderstandȱtheȱmeaningȱbehindȱthatȱdataȱ
thatȱcementedȱhisȱdecisionȱtoȱstayȱinȱthisȱfieldȱasȱaȱcareer.ȱHeȱbeganȱtoȱappreciateȱtheȱgoalȱofȱproducingȱstudyȱreportsȱsummarizingȱtheȱsafetyȱandȱefficacyȱresultsȱofȱclinicalȱtrials.ȱȱ
ȱprogrammingȱandȱdevelopingȱgoodȱSASȱprogrammingȱskills,ȱtheȱoutputȱproducedȱbyȱhisȱprogramsȱwereȱ
moreȱimportantȱthanȱtheȱSASȱprograms.ȱȱHeȱbeganȱtoȱrealizeȱthatȱthisȱwasȱtheȱpivotalȱaspectȱofȱtheȱBionalystȇsȱjob.ȱȱTheȱ
Biostatistician,ȱwhoȱwasȱtheȱBioanalystȇsȱclient,ȱwantedȱtoȱreceiveȱqualityȱoutputȱtablesȱrepresentingȱ
theȱstudyȱdataȱandȱitsȱanalysesȱresults.ȱȱTheyȱwereȱnotȱinterestedȱinȱtheȱqualityȱofȱtheȱSASȱprogramȱusedȱtoȱcreateȱtheȱtables,ȱsoȱlongȱasȱtheyȱ
producedȱaccurateȱresults.ȱȱȱTheȱunderstandingȱofȱtheȱdiseaseȱthatȱheȱwasȱworkingȱonȱwasȱanotherȱfascinatingȱaspectȱofȱtheȱjob.ȱȱHeȱisȱnotȱclinically
asȱaȱMDȱorȱaȱRN,ȱbutȱhisȱinterestȱinȱresearchȱandȱlearningȱaboutȱtheȱdiseaseȱrelatedȱtoȱaȱgivenȱdrugȱallowedȱhimȱaȱuniqueȱviewȱ
ofȱtheȱdata.ȱȱThisȱwasȱaȱwindowȱthroughȱtheȱdataȱwhichȱprovidedȱmeaningȱthatȱbecameȱessentialȱinȱhisȱwork.ȱȱTheȱinteractionsȱ
withȱotherȱteamȱmembersȱmostlyȱinvolvedȱcommunicatingȱwithȱtheȱBiostatistician.ȱȱHowever,ȱitȱalsoȱincludedȱinteractingȱwithȱ
theȱotherȱclinicalȱteamȱmembers,ȱsuchȱasȱtheȱMDȱinȱchargeȱofȱtheȱproject.ȱȱTheȱBiostatisticianȱandȱBioanalystȱworkedȱtogetherȱ
closelyȱinȱanalyzingȱandȱproducingȱreportȱtablesȱandȱgraphs.ȱȱEvenȱthoughȱtheȱmeaningȱofȱtheȱstatisticsȱis
statistician,ȱitȱoftenȱendedȱupȱwithȱtheȱBioanalystȱneedingȱtoȱinterpretȱtheirȱinstructionsȱtoȱfillȱinȱtheȱgaps.ȱȱThisȱmultiȬfacetedȱ
aspectȱofȱtheȱjobȱkeptȱDavidȱinterestedȱinȱtheȱworkȱwhichȱsustainedȱandȱrationalizedȱhisȱlongȱcommuteȱforȱ12ȱyears.ȱ
3AlthoughȱtheȱdataȱkeptȱDavidȱinterested,ȱheȱdidȱexploreȱtechnicalȱaspectsȱofȱtheȱjobȱasȱwell.ȱȱHeȱcontinuedȱtoȱdevelopȱhisȱSASȱ
programmingȱskillsȱbyȱtakingȱsomeȱdatabaseȱdesignȱcoursesȱatȱU.C.ȱBerkeleyȱExtension.ȱȱThisȱgaveȱhimȱtheȱopportunityȱtoȱ
workȱonȱseveralȱOracleȱdatabaseȱprojects.ȱȱHeȱalsoȱwasȱpartȱofȱtheȱinitialȱRx/Clinicalȱdevelopmentȱteam,ȱaȱjointȱventureȱ
betweenȱOracleȱandȱSyntexȱthatȱledȱtoȱOracleȱClinical,ȱtheȱleadingȱclinicalȱtrialȱdatabaseȱmanagementȱsystemȱusedȱinȱtheȱ
pharmaceuticalȱindustry.ȱȱȱȱHeȱbeganȱtoȱtakeȱonȱmanagementȱresponsibilities,ȱmanagingȱbothȱpeopleȱandȱprojectsȱatȱSyntex.ȱȱThisȱcontinuedȱonȱ
inȱhisȱcareerȱatȱChironȱinȱEmeryville.ȱȱHeȱmodestlyȱattributedȱtheȱmanagementȱofȱpeopleȱasȱbeingȱanȱeasyȱjobȱbecauseȱtheȱpeopleȱheȱ
workedȱwithȱwereȱcapableȱandȱgoodȱtoȱworkȱwith.ȱȱSinceȱheȱhadȱaȱgoodȱunderstandingȱofȱwhatȱitȱtookȱtoȱperformȱasȱaȱ
ȱidentifyȱpeopleȱwhoȱhadȱtheȱrightȱbalanceȱofȱresearchȱandȱinterestȱinȱtheȱdata,ȱalongȱwithȱtheȱ
technicalȱprogrammingȱskills.ȱȱItȱwasȱaȱcombinationȱofȱhavingȱtheȱtenacityȱtoȱunderstandingȱtheȱclinicalȱaspectsȱofȱtheȱdataȱ
whileȱhavingȱtheȱtechnicalȱskillsȱtoȱdeliverȱanalysis.ȱȱThisȱwasȱwhatȱDavidȱhadȱstrivedȱ
forȱhimselfȱandȱwasȱwhatȱheȱlookedȱforȱ inȱformingȱtheȱteamsȱwhichȱheȱmanaged.ȱȱDavidȱisȱnowȱtheȱAssociateȱDirectorȱofȱBioanalysisȱatȱNovartisȱ(formerlyȱChiron).ȱȱHeȱisȱveryȱproudȱofȱtheȱteamȱthatȱheȱputȱ
togetherȱsinceȱheȱstartedȱatȱChiron.ȱȱDavidȇsȱfirstȱgoalȱatȱChironȱwasȱto
ȱestablishȱaȱstandardȱsetȱofȱreportingȱmacrosȱwhichȱwouldȱhandleȱtheȱstandardȱCRFȱ(CaseȱReportȱForms).ȱȱHeȱdecidedȱtoȱhaveȱhisȱBioanalystsȱbalanceȱtheirȱworkloadȱofȱ
producingȱtheȱdayȬtoȬdayȱanalysisȱandȱreportingȱworkȱwithȱdevelopingȱandȱmaintainingȱaȱstandardȱlibraryȱofȱmacroȱsoftware.ȱȱ
Theȱstandardȱsoftwareȱmostlyȱfocusedȱonȱgeneratingȱsafetyȱsummariesȱsinceȱtheȱefficacyȱdataȱusuallyȱvariedȱtooȱmuchȱ
betweenȱprojects.ȱȱTheȱdifferenceȱamongȱstudiesȱdidnȇtȱlendȱitselfȱtoȱstandardization.ȱȱHeȱproceededȱtoȱassignȱPhilȱtoȱworkȱonȱ
Labȱdata,ȱFrancesȱtoȱdevelopȱmacrosȱforȱAdverseȱEvents,ȱRobȱtoȱworkȱonȱDemographicsȱandȱConmedȱwhileȱDavidȱhimself
ȱworkedȱonȱtheȱDosingȱinformation.ȱȱItȱwasȱaȱmanagementȱstyleȱthatȱallowedȱhimȱtoȱparticipateȱinȱtheȱworkȱfirsthand,ȱwhileȱ
motivatingȱtheȱteamȱtoȱdevelopȱsoftware.ȱȱThisȱwasȱallȱimplementedȱonȱtopȱofȱtheȱnormalȱstudyȱanalysisȱworkȱthatȱtheyȱhadȱtoȱ
do.ȱȱHeȱenjoyedȱworkingȱonȱhisȱmacroȱcomponentȱwhichȱorganizedȱdosingȱinformationȱintoȱaȱdosingȱanalysisȱfileȱandȱthenȱ
joinedȱthisȱfileȱwithȱtimeȬdependentȱeventsȱinȱaȱstudy.ȱȱThisȱallowedȱintegratingȱaȱsubjectȇsȱdosingȱexperienceȱwithȱotherȱstudyȱ
dataȱsuchȱasȱadverseȱeventȱandȱefficacyȱdata.ȱȱForȱexample,ȱanȱadverseȱeventȱcanȱoccurȱatȱanyȱspecificȱtime
Hisȱmacroȱwouldȱthenȱmergeȱthisȱdataȱwithȱtheȱdosingȱinformationȱandȱaddedȱvariablesȱsuchȱasȱtheȱexactȱdose,ȱtheȱ
cumulativeȱdose,ȱtimeȱsinceȱlastȱdose,ȱetc...ȱȱThisȱwasȱderivedȱinȱassociationȱwithȱtheȱadverseȱeventȱofȱthisȱevent.ȱ
Davidȇsȱapproachȱtoȱdevelopingȱtheȱmacroȱsystemȱ wasȱtoȱstandardizeȱanyȱareaȱwhereȱtheȱpotentialȱuseȱoutweighedȱtheȱdevelopmentȱandȱvalidationȱcosts.ȱȱHavingȱaȱstandardȱmacroȱsystemȱavailableȱprovidedȱforȱconsistentȱanalysesȱacrossȱstudies,ȱ
projectsȱandȱoutput.ȱȱItȱalsoȱpreventedȱtheȱprogrammerȱfromȱhavingȱtoȱdoȱrepetitiveȱtasks.ȱȱThisȱallowedȱthemȱtoȱfocusȱonȱtheȱ
uniqueȱefficacyȱaspectsȱofȱeachȱstudy.ȱȱItȱmadeȱtheȱjobȱeasierȱandȱmoreȱefficientȱforȱtheȱBioanalyst.ȱȱHisȱteamȱwasȱalsoȱmoreȱ
engagedȱandȱinterestedȱsinceȱtheȱworkȱwasȱmoreȱdynamicȱandȱbecameȱmoreȱlikeȱaȱuniqueȱpuzzleȱthatȱneedsȱtoȱbeȱsolvedȱforȱ
everyȱstudy.ȱȱȱ Itȱtookȱaȱyearȱtoȱdevelopȱtheȱlotȱofȱcompetingȱstudyȱanalysisȱwork.ȱȱLaterȱon,ȱitȱtookȱmoreȱtimeȱtoȱimplementȱsubsequentȱversionȱreleasesȱsinceȱtheȱ
programmersȱusuallyȱhadȱprojectȱworkȱthatȱtookȱprecedenceȱoverȱtheȱstandardȱmacroȱdevelopment.
thatȱthisȱwasȱaȱmoreȱcostȱeffectiveȱapproach.ȱȱByȱgivingȱtheȱdevelopmentȱeffortsȱtoȱtheȱseniorȱprogrammersȱwhoȱworkȱwithȱtheȱ
analysesȱthemselves,ȱtheȱdevelopmentȱofȱsoftwareȱwasȱimplementedȱbyȱtheȱsameȱindividualsȱwhoȱunderstandȱitȱtheȱmost.ȱȱȱ
Davidȱhasȱaȱlowȱkeyȱapproachȱtoȱmanagingȱhisȱpeople.ȱȱHeȱsetsȱoutȱgoalsȱandȱexpectsȱhisȱpeopleȱtoȱworkȱconscientiouslyȱandȱ
autonomously.ȱȱHeȱdoesȱnotȱseeȱhimselfȱasȱhavingȱaȱdraconianȱstyleȱbutȱratherȱaȱgentleȱcoachȱapproach.ȱȱDavidȱperformsȱpeerȱ
reviewsȱandȱmakesȱsuggestionsȱbutȱinȱgeneral,ȱleavesȱhisȱpeopleȱalone.ȱȱHeȱseesȱthatȱitȱisȱthisȱfreedom
eachȱindividualȱtoȱthriveȱandȱdiscoverȱtheȱuniqueȱbalanceȱofȱvariousȱskillsȱtoȱbeȱaȱsuccessfulȱBioanalyst.ȱ
Geneȇsȱintroductionȱtoȱcomputersȱandȱtechnologyȱstartedȱbackȱinȱhighȱschoolȱinȱtheȱ70ȇsȱwhenȱheȱusedȱtheȱTexasȱInstrumentȱ
calculatorsȱthatȱallowedȱhimȱtoȱprogramȱequations.ȱȱHeȱthenȱlearnedȱassemblyȱlanguageȱandȱmachineȱcodeȱonȱDECȱPDPȬ11ȱ
andȱZilogȱZȬ80ȱmicroprocessors.ȱȱGeneȱenjoyedȱworkingȱatȱtheȱmachineȱlevelȱofȱtheseȱ16ȱandȱ8Ȭbitȱmachinesȱbecauseȱitȱtaughtȱ
4himȱtheȱfundamentalsȱandȱrigorousȱapproachȱtowardsȱprogramming,ȱincludingȱdebuggingȱprograms.ȱȱHeȱthenȱprogressedȱ
intoȱlearningȱtheȱBASICȱlanguage.ȱȱInȱadditionȱtoȱGeneȇsȱdispositionȱtowardsȱproblemȱsolvingȱwhichȱattractedȱGeneȱtowardsȱ
computers,ȱheȱalsoȱhadȱinterestȱinȱbecomingȱaȱȈdoctorȈȱsoȱheȱstartedȱhisȱundergraduateȱworkȱatȱJohnsȱHopkinsȱin
degreeȱinȱBiomedicalȱEngineering.ȱȱThisȱcombinedȱhisȱclinicalȱaspirationsȱwithȱhisȱanalytical,ȱresearchȬoriented,ȱengineeringȱ
ambitions.ȱTheȱuniversityȱsetting,ȱincludingȱsummerȱjobs,ȱgaveȱGeneȱexperienceȱworkingȱonȱresearchȱprojects.ȱȱEvenȱthoughȱheȱspentȱaȱ
lotȱofȱtimeȱinȱtheȱlabȱworkingȱonȱanimals,ȱtechnologyȱwasȱeverȱpresent.ȱȱ
Forȱexample,ȱtheȱresearchȱlabsȱhadȱaȱRadioȱShackȱTRSȬ80ȱcomputerȱcontrollingȱaȱdogȇsȱheartȱrate.ȱȱTheȱcombinationȱofȱtechnologyȱasȱappliedȱtoȱmedicalȱresearchȱwasȱfascinatingȱ
becauseȱitȱwasȱveryȱȈFrankensteinȈ.ȱȱSimilarȱtoȱhowȱtinkeringȱwithȱearlyȱ8ȬbitȱcomputersȱgaveȱGeneȱtheȱfundamentalsȱofȱ
softwareȱdevelopment,ȱtheȱlaboratoryȱheȱworkedȱinȱgaveȱhimȱaȱfoundationȱforȱmedicalȱresearchȱwhichȱlaterȱaidedȱhimȱinȱhisȱ
workȱonȱclinicalȱtrials.ȱAlthoughȱheȱdidȱnotȱuseȱSASȱyet,ȱJohnsȱHopkinsȱandȱhisȱgraduateȱworkȱatȱCaseȱWesternȱReserveȱUniversityȱdidȱallowȱGeneȱ
toȱworkȱwithȱBMPD.ȱȱThisȱwasȱanotherȱstatisticalȱsoftwareȱpackageȱatȱtheȱtimeȱwhichȱallowedȱhimȱtoȱrunȱstatisticalȱmodelsȱ
suchȱasȱonȱANOVA,ȱTȬTESTȱwhichȱwereȱinȱroutinesȱsimilarȱtoȱSASȱPROCs.ȱ
OneȱofȱtheȱfirstȱjobsȱthatȱGeneȱstartedȱtoȱworkȱonȱafterȱhisȱMastersȱdegreeȱinȱBiomedicalȱEngineeringȱwasȱworkingȱas
ManagerȱinȱLosȱAngelesȱforȱaȱnonȬprofitȱorganizationȱnamedȱLosȱAngelesȱRegionalȱFamilyȱPlanningȱCouncil.ȱȱHeȱworkedȱonȱ
projectsȱdealingȱwithȱclinicalȱtrialsȱonȱcontraceptivesȱsuchȱasȱtheȱIUDȱandȱnonȬlatexȱcondoms.ȱȱGeneȱworkedȱcloselyȱwithȱtheȱ
dataȱinȱaȱroleȱasȱaȱȱDBA/DataȱManagerȱusingȱdBaseȱIIIȱwithȱtasksȱsuchȱasȱdefiningȱtheȱdatabaseȱstructureȱandȱsettingȱupȱdataȱ
entryȱscreens.ȱȱHeȱwasȱalsoȱintroducedȱtoȱSASȱbutȱhadȱlimitedȱresourcesȱsinceȱthereȱwereȱnoȱotherȱSASȱprogrammersȱinȱtheȱ
entireȱorganization.ȱȱHeȱthereforeȱreferredȱtoȱhisȱmanagerȱwhoȱhadȱaȱstatisticalȱbackground,ȱbutȱwasȱlimited
knowledgeȱandȱheȱalsoȱusedȱSASȱreferenceȱmanuals.ȱȱGeneȱenjoyedȱlearningȱprogrammingȱonȱhisȱownȱandȱpurchasedȱ
additionalȱSASȱmanualsȱdirectlyȱfromȱSASȱInstituteȱtoȱteachȱtheȱSASȱlanguageȱtoȱhimself.ȱȱȱ.ȱ
AsȱaȱDatabaseȱManager,ȱGeneȱworkedȱcloselyȱonȱdataȱdiscrepanciesȱsuchȱasȱprogrammingȱeditȱchecksȱandȱ
theȱprocessȱofȱtransferringȱdataȱfromȱdBaseȱtoȱSASȱviaȱflatȱASCIIȱfiles.ȱȱOnceȱheȱhadȱtheȱdataȱinȱSAS,ȱheȱwasȱableȱtoȱgenerateȱdescriptiveȱ
statisticsȱusingȱPROCȱMEANS,ȱFREQȱandȱUNIVARIATE.ȱȱTheȱprogrammingȱpracticesȱbeingȱconductedȱwereȱnotȱasȱformallyȱ
structuredȱasȱinȱaȱtypicalȱclinicalȱtrial.ȱȱAsȱaȱpolicy,ȱpermanentȱanalysisȱfilesȱwereȱneverȱsaved,ȱbutȱinsteadȱtheȱsameȱSASȱ
programȱwouldȱimportȱtheȱsourceȱdata,ȱcreateȱtemporaryȱanalysisȱfiles,ȱandȱdirectlyȱgenerateȱstatisticalȱreportsȱ.ȱȱAtȱthisȱpoint,ȱ
GeneȱonlyȱdabbledȱinȱSASȱandȱitȱhadȱnotȱyetȱbecomeȱhisȱmainȱjob.ȱ
toȱtheȱSanȱFranciscoȱBayȱAreaȱtoȱworkȱforȱaȱmedicalȱdeviceȱcompanyȱdealingȱwithȱlaserȱeyeȱ
surgeryȱnamedȱVISX.ȱȱHeȱsoughtȱoutȱthisȱnewȱpositionȱasȱaȱbiomedicalȱengineer,ȱsinceȱitȱmatchedȱhisȱcollegeȱeducation.ȱȱ
Althoughȱheȱdidȱinitiallyȱaccomplishȱsomeȱengineeringȱimprovementsȱonȱtheirȱproduct,ȱhisȱbackgroundȱinȱworking
clinicalȱdataȱultimatelyȱdictatedȱhisȱroleȱatȱVISX.ȱȱȱSinceȱGeneȱhadȱbeenȱworkingȱasȱaȱdataȱmanager,ȱtheyȱhadȱplacedȱhimȱinȱaȱ
positionȱworkingȱcloselyȱwithȱtheirȱDOSȬbasedȱParadoxȱdatabaseȱwithȱanalysisȱinȱSAS.ȱȱHeȱcontinuedȱworkingȱonȱtheȱdataȱ
discrepancyȱmanagementȱwhichȱwasȱthenȱexportedȱtoȱSASȱforȱanalysis.ȱȱSinceȱthisȱmedicalȱdeviceȱwasȱVISXȇsȱmajorȱproductȱ
andȱitsȱmajorȱcompetitor,ȱSummitȱTechnologies,ȱwasȱdevelopingȱaȱsimilarȱproduct,ȱthereȱwereȱtremendousȱtimelineȱpressuresȱ
toȱgetȱtheȱdataȱsubmittedȱtoȱtheȱFDAȱforȱapprovalȱandȱbeatȱtheirȱcompetitorȱtoȱtheȱopenȱmarket.ȱȱSoȱVISXȱdecidedȱtoȱhire
consultantsȱtoȱassistȱinȱachievingȱthisȱgoal.ȱȱAlthoughȱmarketingȱapprovalȱforȱVISXȇsȱproductȱwasȱvirtuallyȱcompletedȱinȱ
CanadaȱandȱEurope,ȱtheyȱwereȱstillȱinȱtheȱprocessȱofȱgettingȱapprovalȱinȱtheȱUSAȱandȱthereforeȱwereȱsubmittingȱtheȱclinicalȱ
trialȱreportsȱtoȱtheȱFDA.ȱȱPartȱofȱGeneȇsȱresponsibilitiesȱwasȱtoȱguideȱtheȱSASȱconsultantsȱinȱtheirȱjob.ȱȱHeȱwasȱnotȱtheirȱformalȱ
managerȱbutȱheȱworkedȱcloselyȱwithȱthemȱsinceȱheȱunderstoodȱtheȱmeaningȱofȱtheȱdataȱandȱhadȱsomeȱexperienceȱwithȱSASȱ
programming.ȱȱHeȱcouldȱbridgeȱtheȱgapȱbetweenȱwhatȱtopicsȱtheȱstatisticiansȱwantedȱtoȱreportȱonȱand
couldȱaccomplishȱtheseȱtasks.ȱȱThisȱwasȱanȱeyeȱopeningȱexperienceȱinȱthatȱforȱtheȱfirstȱtime,ȱheȱdiscoveredȱthatȱthereȱexistedȱ
suchȱaȱjobȱwhereȱyouȱcanȱprogramȱinȱSASȱ100%ȱofȱtheȱtimeȱasȱaȱjob!ȱȱThisȱintriguedȱhimȱsinceȱheȱdidȱnotȱcareȱforȱtheȱ
administrativeȱaspectȱofȱtheȱjobsȱheȱhadȱseen.ȱȱTheseȱSASȱconsultantsȱwouldȱjustȱcomeȱin,ȱfocusȱonȱtheirȱworkȱandȱwereȱnotȱ
involvedȱinȱasȱmuchȱmeetingsȱorȱofficeȱpolitics.ȱȱTheseȱguysȱwereȱȈdoȬersȈȱnotȱȈtalkersȈ.ȱȱTheyȱdidȱnotȱhaveȱadministrativeȱ
tasksȱsuchȱasȱdealingȱwithȱyearlyȱperformanceȱreviewsȱandȱwereȱjustȱthereȱtoȱdoȱaȱspecificȱjob.ȱȱGeneȱsawȱthisȱasȱaȱrefreshingȱ
alternativeȱwayȱofȱworking.ȱȱHeȱalsoȱlikedȱhowȱtheseȱconsultantsȱhadȱopportunitiesȱtoȱexperienceȱhowȱdifferentȱcompaniesȱ
operatedȱsinceȱtheyȱdidȱnotȱstayȱatȱoneȱcompanyȱasȱlongȱasȱpermanentȱemployees.ȱȱThisȱvarietyȱofȱworkȱ
keptȱtheseȱconsultantsȱonȱtheirȱtoesȱandȱpreventedȱthemȱfromȱfallingȱintoȱaȱrut,ȱwithȱboredomȱandȱstagnation.ȱ
5ThisȱinsightȱencouragedȱGeneȱtoȱcontinueȱtoȱlearnȱmoreȱaboutȱSASȱthroughȱtheȱuseȱofȱtheȱfewȱSASȱmanualsȱheȱhadȱaccessȱto.ȱȱ
Heȱalsoȱlearnedȱbyȱseeingȱsampleȱcodeȱthatȱtheseȱconsultantsȱwouldȱshareȱwithȱhim.ȱȱGeneȱwasȱnowȱspendingȱ50%ȱofȱhisȱtimeȱ
workingȱonȱSASȱwhichȱwasȱmore ȱthanȱheȱhadȱeverȱdoneȱbefore.ȱThereȱwereȱcorporateȱchallengesȱatȱVISXȱwhichȱleadȱtoȱlayoffs.ȱȱThisȱandȱotherȱmanagementȱturmoilȱleadȱGeneȱtoȱtryȱoutȱtheȱ
consultingȱworldȱstartingȱwithȱworkȱatȱRocheȱBiosciences.ȱȱItȱstartedȱoutȱasȱaȱ3ȱmonthȱcontractȱwhichȱisȱtypicalȱforȱ
anȱinitialȱcontract.ȱȱThisȱintroductoryȱperiodȱallowedȱtheȱcompanyȱtoȱevaluateȱtheȱconsultantȱtoȱseeȱifȱitȱworkedȱoutȱwithoutȱmakingȱaȱ
bigȱcommitment.ȱȱIfȱthingsȱwentȱsmoothlyȱandȱthereȱwasȱworkȱtoȱbeȱdone,ȱitȱwasȱnormallyȱextended.ȱȱGeneȱworkedȱonȱtheȱ
precursorȱtoȱOracleȱClinicalȱknownȱasȱRx/ClinicalȱwhichȱisȱtheȱclinicalȱtrialsȱrelationalȱdatabaseȱjointlyȱdevelopedȱbyȱOracleȱ
andȱSyntex,ȱwhichȱlaterȱbecameȱRocheȱBiosciences.ȱȱEvenȱthoughȱheȱstartedȱoutȱworkingȱinȱtheȱroleȱasȱaȱdataȱmanagement,ȱ
GeneȱgrewȱintoȱtheȱpositionȱofȱaȱSASȱprogrammerȱandȱcontinuedȱtoȱworkȱasȱaȱconsultantȱatȱRocheȱforȱthreeȱ
andȱaȱhalfȱyears.ȱȱThisȱwasȱwhereȱheȱlearnedȱtheȱmajorityȱofȱhisȱSASȱprogrammingȱskills.ȱȱDuringȱtheseȱsameȱyears,ȱGeneȱnoticedȱthatȱthereȱ
wereȱsomeȱindividualsȱinȱthisȱlargeȱorganizationȱwhoȱbeganȱtoȱhaveȱaȱȈDMVȈȱmentality.ȱȱAfterȱyearsȱofȱworkingȱinȱaȱ
bureaucraticȱorganization,ȱtheyȱlackedȱtheȱdesireȱtoȱlearnȱnewȱthingsȱandȱbecameȱlessȱmotivated.ȱȱSomeȱofȱhisȱcolleaguesȱwereȱ
inȱtheȱsameȱcompanyȱforȱtensȱofȱyears.ȱȱHeȱbeganȱtoȱseeȱhowȱthisȱstagnationȱcreptȱintoȱhisȱworkȱroutineȱasȱwell,ȱevenȱthoughȱ
heȱwasȱaȱconsultant.ȱȱThisȱrealizationȱwokeȱGeneȱupȱtoȱtheȱrealityȱthatȱperhapsȱ
heȱwasȱalsoȱfallingȱintoȱthisȱstagnation,ȱandȱkeepingȱtrueȱtoȱhisȱoriginalȱreasonsȱforȱbecomingȱaȱconsultant,ȱheȱdecidedȱtoȱmakeȱaȱchange.ȱ
GeneȱventuredȱintoȱaȱshortȱcontractȱwithȱQuintilesȱPacificȱdownȱtheȱPeninsulaȱinȱMountainȱView.ȱȱThisȱwasȱtheȱfirstȱtimeȱheȱ
workedȱinȱaȱClinicalȱResearchȱOrganizationȱ(CRO)ȱwhichȱwasȱdifferentȱfromȱhisȱexperienceȱwithȱaȱpharmaceuticalȱcompany.ȱȱ
Hisȱinitialȱthoughtsȱwereȱthatȱsinceȱitȱwasȱaȱserviceȱorganization,ȱtheȱworkȱwouldȱbeȱvariedȱsinceȱtheyȱwereȱservicingȱmanyȱ
differentȱclientsȱatȱtheȱsameȱtime.ȱȱItȱturnedȱoutȱhoweverȱthatȱmanyȱclientsȱrelyȱonȱtheȱCROȱtoȱ
dictateȱtheȱstandardsȱandȱtheȱwayȱtheȱworkȱwasȱdone.ȱȱItȱthereforeȱturnedȱoutȱthatȱtheȱworkȱwasȱstillȱdoneȱmostlyȱinȱtheȱsameȱwayȱacrossȱdifferentȱclientsȱ
andȱprojects.ȱTheȱdesireȱtoȱlearnȱnewȱthingsȱandȱworkȱinȱdifferentȱenvironmentsȱdroveȱGeneȱtoȱcontinueȱintoȱotherȱprojects.ȱȱHeȱhadȱheard
ȱfromȱotherȱSASȱconsultantsȱthatȱfindingȱjobsȱonȱyourȱownȱwasȱtheȱwayȱtoȱearnȱtheȱbiggestȱsalary.ȱȱDespiteȱthisȱfact,ȱGeneȱ
reliedȱonȱjobȱplacementȱfirmsȱsuchȱasȱTrilogyȱandȱASGȱtoȱlandȱhimȱnewȱopportunities.ȱȱGeneȱpreferredȱworkingȱinȱthisȱ
mannerȱbecauseȱheȱreliedȱonȱtheȱmarketingȱresourcesȱofȱtheseȱfirmsȱtoȱfindȱhimȱtheȱprojectsȱsoȱheȱcouldȱjustȱfocusȱonȱȇdoingȱ
theȱworkȱandȱnotȱtryingȱtoȱfindȱtheȱworkȇ.ȱȱIfȱoneȱisȱlucky,ȱthereȱisȱalwaysȱsomethingȱnewȱandȱinterestingȱtoȱlearnȱwithinȱeachȱ
workȱenvironment.ȱȱAtȱPharmacyclics,ȱheȱworkedȱwithȱtheȱTrialexȱSystemȱwhich
ȱwasȱaȱbrowserȱbasedȱthinȱclientȱsoftwareȱtoȱmanageȱreportsȱandȱanalysisȱfilesȱheȱcreatedȱusingȱSAS.ȱȱNowȱlivingȱinȱNorthȱCarolina,ȱhisȱcurrentȱprojectȱisȱforȱSchwarzȱ
Bioscience,ȱwhichȱisȱactuallyȱbasedȱinȱGermany.ȱȱHeȱhoweverȱworksȱatȱhomeȱmostȱofȱtheȱtimeȱconnectingȱtoȱserversȱinȱ
Geneȱstarted,ȱtheyȱdidȱnotȱhaveȱcubeȱspaceȱinȱtheirȱNorthȱCarolinaȱoffice,ȱsoȱtheȱarrangementȱwasȱforȱhimȱtoȱ
connectȱviaȱhisȱcableȱmodemȱfromȱhomeȱandȱworkȱthroughȱaȱremoteȱdesktopȱwithinȱaȱCitrixȱenvironment.ȱȱMostȱofȱtheȱtime,ȱitȱ
workedȱwellȱbutȱonceȱinȱaȱwhile,ȱhisȱkeyboardȱwouldȱspontaneouslyȱswitchȱtoȱaȱGermanȱstyleȱkeyboardȱandȱhisȱUltraeditȱ
editorȱwouldȱcreateȱunexpectedȱcharactersȱsoȱheȱwouldȱhaveȱtoȱlogȱoutȱandȱbackȱinȱtoȱuseȱanȱEnglishȱkeyboardȱagain.ȱ
DifferentȱorganizationsȱhaveȱdifferentȱapproachesȱtowardsȱvalidationȱofȱSASȱprograms.ȱȱThisȱisȱpartlyȱdueȱtoȱvaryingȱ
interpretationsȱofȱtheȱregulationsȱandȱalsoȱdueȱtoȱhowȱdifferentȱmanagersȱandȱorganizationsȱfunction.ȱȱAtȱthisȱcurrentȱproject,ȱ
SchwarzȱBiosciencesȱhasȱanȱapproachȱofȱvalidatingȱallȱtheȱoutputȱ100%.ȱȱThisȱmeansȱthatȱthereȱisȱanȱindependentȱprogrammerȱ
whoȱwouldȱproduceȱtheȱsameȱnumbersȱinȱaȱseparateȱSASȱprogramȱstoredȱinȱaȱseparateȱSAS
ȱdatasetȱwhichȱisȱdistinctȱfromȱthoseȱthatȱareȱmeantȱtoȱbeȱsubmittedȱtoȱtheȱFDA.ȱȱThisȱmeansȱthatȱthereȱisȱaȱseparateȱprogramȱthatȱperformsȱaȱPROCȱ
COMPAREȱtoȱensureȱthatȱtheȱtwoȱsetsȱofȱnumbersȱareȱidenticalȱbeforeȱitȱisȱdeemedȱȈvalidatedȈ.ȱȱWhenȱGeneȱfirstȱstarted,ȱheȱ
primarilyȱdidȱtheȱduplicateȱvalidationȱtypeȱprogramming.ȱȱNowȱthatȱheȱhasȱbeenȱonȱtheȱprojectȱlonger,ȱheȱisȱdoingȱmoreȱofȱtheȱ
originalȱprogrammingȱthatȱwillȱbeȱpartȱofȱtheȱsubmission.ȱȱȱSinceȱheȱworksȱremotely,ȱGeneȇsȱmainȱmethodȱofȱcommunicatingȱwithȱhisȱcoworkersȱisȱthroughȱemail.ȱȱNinetyȱpercentȱofȱtheȱ
time,ȱhisȱemailȱandȱcommunicationsȱareȱdealingȱwithȱdetailedȱinformationȱsuchȱasȱdata,ȱfile,ȱandȱvariableȱnames.ȱȱHeȱdoesȱ
recognizeȱthatȱatȱtimes,ȱitȱdoesȱtakeȱaȱlittleȱlongerȱtoȱdescribeȱorȱshowȱsomeoneȱsomethingȱinȱemailȱwhereasȱifȱheȱwereȱtoȱbeȱ
physicallyȱinȱfrontȱofȱthem,ȱitȱwouldȱbeȱ faster.ȱȱȱGeneȱhasȱfoundȱmanyȱcreativeȱandȱresourcefulȱwaysȱtoȱlearnȱandȱreinventȱhimselfȱasȱaȱSASȱconsultant.ȱȱEvenȱbeforeȱheȱstartedȱ
workingȱprofessionally,ȱhisȱinterestȱinȱ8Ȭbitȱmicroprocessorsȱandȱworkingȱatȱtheȱelectronicȱcircuitryȱlevelȱcoincidedȱwithȱhisȱ
tinkeringȱtendenciesȱandȱattentionȱtoȱdetailȱpersonality.ȱȱThisȱinclination
ȱtoȱfocusȱonȱtheȱdetailsȱgrewȱasȱheȱworkedȱwithȱdataȱdiscrepancies.ȱȱIfȱGeneȱwereȱtoȱfindȱoneȱdataȱissue,ȱitȱwouldȱbotherȱhimȱtoȱjustȱleaveȱtheȱrestȱalone.ȱȱHeȱhasȱtoȱthenȱinvestigateȱ
6theȱrestȱtoȱensureȱthatȱthereȱareȱnoȱsuchȱproblemsȱoccurringȱelsewhere.ȱȱThereȱisȱaȱcertainȱsatisfactionȱandȱcomfortȱknowingȱ
thatȱheȱcanȱferretȱoutȱallȱtheȱdiscrepanciesȱthatȱexistȱinȱaȱdatabase.ȱAnȱinclinationȱtoȱfocusȱonȱdetailsȱalsoȱhelpsȱinȱdebuggingȱ
ȱattendȱSASȱtrainingȱcourses.ȱȱInstead,ȱGeneȱgravitatedȱtowardsȱgettingȱhisȱconsultantȱfirmȱtoȱpayȱforȱtheȱSASȱ
referenceȱmanualsȱheȱrequested.ȱȱHeȱactuallyȱappreciatedȱtheȱcostȱeffectivenessȱofȱuserȱmanualsȱsinceȱitȱisȱaȱcontinuousȱsourceȱ
ofȱknowledgeȱthatȱcanȱbeȱreferencedȱoverȱandȱover.ȱȱGoodȱreferenceȱmanualsȱhadȱsampleȱ
codeȱthatȱcouldȱbeȱusedȱasȱtemplatesȱtoȱalgorithmsȱinȱrealȱworldȱapplications.ȱȱGeneȱstartedȱhisȱownȱpersonalȱelectronicȱlibraryȱofȱsampleȱcodeȱthatȱheȱrefersȱtoȱonȱ
occasions.ȱȱThisȱprocessȱstartedȱinȱhisȱearlyȱdaysȱwhenȱheȱfirstȱstartedȱworkingȱwithȱSASȱconsultantsȱpriorȱtoȱhimȱbecomingȱaȱ
fullȱtimeȱSASȱprogrammer.ȱȱSinceȱthen,ȱheȱcontinuedȱaddingȱtoȱitȱfromȱotherȱprogrammers,ȱincludingȱoriginalȱalgorithmsȱheȱ
cameȱupȱwithȱandȱcodeȱthatȱheȱacquiredȱatȱSASȱconferences.ȱȱRegardingȱSASȱconferences,ȱheȱseesȱSUGIȱbeingȱtheȱbiggestȱandȱ
theȱmostȱexpensive.ȱȱThereȱseemsȱtoȱbeȱaȱlargerȱrepresentationȱofȱmoreȱseasonedȱ
SASȱprogrammersȱandȱmanagersȱthatȱattendȱSUGIȱasȱcomparedȱtoȱotherȱSASȱconferences.ȱȱHeȱseesȱitȱasȱnotȱnecessarilyȱfocusedȱonȱtheȱPharmaceuticalȱindustryȱsoȱitȱisȱonlyȱ
byȱchanceȱtoȱfindȱaȱpaperȱwithȱsubstanceȱandȱrelevance.ȱȱGeneȱprefersȱtheȱsmallerȱregionalȱconferencesȱorȱPharmaSUGȱwhereȱ
thereȱisȱmoreȱdiversityȱofȱattendeesȱandȱtheȱfocusȱofȱtheȱtalksȱseemsȱtoȱbeȱmoreȱrelevantȱforȱhim.ȱȱRecently,ȱheȱhadȱsharedȱhisȱ
originalȱSASȱapplicationsȱasȱaȱspeakerȱatȱtheseȱconferences.ȱȱGeneȱisȱconstantlyȱsharpeningȱhisȱskillsȱandȱlookingȱforȱinsightȱbyȱ
theseȱmanyȱresourcefulȱapproaches.ȱȱItȱisȱaȱDarwinianȱworldȱwhereȱ ifȱheȱsharpensȱhisȱtoolsȱandȱconstantlyȱreinventsȱhimselfȱbyȱlearningȱnewȱthings,ȱheȱwouldȱsurviveȱandȱthriveȱasȱaȱSASȱprogrammer.ȱ
ȱ ȱ STATISTICALȱPROGRAMMERȱȬȱSUZYȱQȱ There are many career paths. Sometimes, it is the unexpected and unplanned ones that turn out to be the path that best fits your personality and talents. ȱInȱtheȱearlyȱ1960ȇsȱwhenȱSuzyȱwentȱtoȱcollege,ȱtheyȱdidȱnotȱhaveȱcomputerȱscienceȱasȱaȱmajor.ȱȱSuzyȱmajoredȱinȱmathematicsȱ
forȱherȱfirstȱtwoȱyearsȱatȱUCȱBerkeley.ȱȱSheȱfoundȱupperȱdivisionȱmathȱclassesȱratherȱdifficultȱandȱdecidedȱtoȱswitchȱtoȱ
psychology,ȱkeepingȱmathȱasȱaȱminor.ȱȱPsychologyȱwasȱaȱveryȱdifferentȱdisciplineȱcomparedȱtoȱmathematicsȱbutȱitȱwasȱveryȱ
inlineȱwithȱherȱinterestȱinȱteaching.ȱȱThroughoutȱherȱacademicȱexperience,ȱthereȱwereȱnoȱcomputerȱclassesȱofferedȱforȱliberalȱ
artsȱmajors.ȱȱTheȱonlyȱtechnologyȱusedȱatȱtheȱtimeȱforȱpsychȱstatisticsȱclassesȱwasȱaȱgiantȱcalculatorȱthatȱlookedȱlikeȱ
aȱ typewriterȱwithȱaȱcrankȱhandleȱforȱtheȱȈenterȈȱkey.ȱSuzyȱgraduatedȱinȱJuneȱ1966ȱandȱplannedȱtoȱgetȱaȱteachingȱcredentialȱstartingȱtheȱfollowingȱfall.ȱȱDuringȱthatȱsummer,ȱsheȱhadȱ
plansȱtoȱworkȱasȱaȱcocktailȱwaitressȱinȱTahoe.ȱȱHerȱfatherȱdidȱnotȱthinkȱthatȱthisȱwasȱaȱfittingȱjobȱafterȱallȱherȱeducation.ȱȱHeȱ
thereforeȱcontactedȱaȱfriendȱtoȱarrangeȱforȱanȱinterviewȱwhichȱresultedȱinȱanȱinternshipȱjobȱatȱIBM.ȱȱSuzyȱwasȱoverwhelmedȱatȱ
firstȱduringȱtrainingȱsinceȱthereȱwasȱaȱgroupȱofȱ41ȱsummerȱinternsȱandȱsheȱwasȱtheȱonlyȱfemale.ȱȱThisȱwasȱherȱfirstȱ
introductionȱtoȱcomputerȱprogrammingȱwhichȱincludedȱlanguagesȱsuchȱasȱCOBOLȱandȱFORTRAN.ȱȱ
executedȱonȱanȱIBMȱ360ȱcomputer.ȱȱSheȱusedȱaȱterminalȱwhichȱranȱIBMȇsȱearlyȱversionȱofȱDOSȱthatȱpreȬdatedȱanyȱPCsȱorȱ
Microsoftȱoperatingȱsystems.ȱȱThisȱjobȱwasȱanȱeyeȱopenerȱforȱSuzyȱsinceȱsheȱwasȱfascinatedȱwithȱtechnologyȱandȱ
programming.ȱȱȱȱonȱherȱcareerȱpathȱtoȱbecomeȱanȱelementaryȱschoolȱteacher.ȱȱSheȱdiscoveredȱthatȱtheȱstudentȱ
teachingȱprogramȱatȱBerkeleyȱwasȱnotȱfullyȱchallengingȱherȱsoȱsheȱquit.ȱȱTheȱinternshipȱpositionȱthatȱsheȱheldȱinȱtheȱpastȱleadȱ
SuzyȱtoȱapplyȱforȱaȱfullȱtimeȱpositionȱwithȱIBMȱasȱaȱSystemsȱ Engineer.ȱȱTheȱjobȱentailedȱdoingȱbothȱprogrammingȱandȱoperatingȱsystemȱupgradesȱalongȱwithȱenhancementsȱforȱclientsȱsuchȱasȱKaiserȱAluminumȱandȱtheȱSFȱChronicle.ȱȱSuzyȱtaughtȱ
programmingȱclassesȱforȱIBMȱtoȱclientsȱinȱCOBOL,ȱRPG,ȱandȱAssemblerȱLanguage.ȱȱSuzyȇsȱhusbandȱservedȱinȱtheȱmilitaryȱ
duringȱthatȱtimeȱsoȱsheȱtraveledȱwithȱhimȱwhileȱjugglingȱprogrammingȱjobsȱandȱsubstituteȱteaching.ȱȱOnceȱtheyȱarrivedȱtoȱtheȱ
SanȱFranciscoȱBayȱArea,ȱSuzyȱstartedȱtoȱworkȱforȱBechtelȱinȱtheirȱcorporateȱITȱdepartmentȱasȱanȱoperatingȱsystemȱ
programmer.ȱSuzyȱtookȱsomeȱtimeȱoffȱtoȱraiseȱaȱfamilyȱbeforeȱsheȱreȬenteredȱtheȱworkȱforce
ȱonȱaȱpartȬtimeȱbasis.ȱȱSheȱtaughtȱAssemblerȱLanguageȱprogrammingȱatȱLaneyȱCollegeȱforȱaȱcoupleȱofȱyears.ȱȱThisȱwasȱrewardingȱbutȱitȱwasȱalsoȱfrustratingȱsinceȱherȱ
studentsȱstruggledȱtoȱgetȱcomputerȱjobsȱafterȱcompletingȱtheirȱprogrammingȱclasses.ȱȱTheyȱhadȱtoȱhaveȱ2ȱyearsȱofȱcomputerȱ
experienceȱbeforeȱtheyȱcouldȱgetȱaȱjobȱinȱtheȱfield,ȱsoȱitȱwasȱveryȱdifficultȱgettingȱthatȱinitialȱfootȱinȱtheȱdoor.ȱȱAfterȱherȱ
7teachingȱposition,ȱSuzyȱworkedȱforȱaȱfreightȱcompanyȱwhereȱsheȱstartedȱoutȱdoingȱdataȱentry.ȱȱSheȱthenȱobtainedȱaȱpromotionȱ
toȱaȱprogrammingȱpositionȱshortlyȱafter.ȱȱInȱthisȱjob,ȱsheȱwasȱresponsibleȱforȱproducingȱlistingsȱandȱsummaryȱtables.ȱȱTheȱ
workȱkeptȱherȱchallengedȱbutȱtheȱdataȱwasȱveryȱdry.ȱȱSheȱhadȱanȱinterestȱinȱscienceȱandȱmedicineȱandȱwantedȱtoȱworkȱinȱtheȱ
newȱbiotechȱindustryȱwhereȱtheȱdataȱdealtȱwithȱhumanȱclinicalȱtrials.ȱȱ
SuzyȱthenȱenrolledȱinȱaȱmastersȱprogramȱatȱHaywardȱStateȱUniversityȱtoȱstudyȱstatistics.ȱȱThisȱenabledȱherȱtoȱgainȱtheȱ
credentialsȱsheȱneededȱtoȱworkȱinȱtheȱbiotechȱindustry.ȱȱThisȱwasȱherȱfirstȱintroductionȱtoȱSAS.ȱȱTheȱUniversityȱalsoȱtaughtȱ
SPSSȱandȱBMDPȱsoftwareȱforȱstatisticalȱmodeling.ȱȱSheȱenjoyedȱtheȱfactȱthatȱtheȱclassedȱwereȱsmallȱwithȱonlyȱbetweenȱ20ȱtoȱ30ȱ
studentsȱperȱclass.ȱȱThisȱincreasedȱtheȱinteractionȱbetweenȱstudentsȱandȱprofessors.ȱȱSheȱwasȱoriginallyȱplanningȱto
statisticianȱbutȱrealizedȱthatȱmostȱcompaniesȱrequireȱaȱPhDȱinȱstatisticsȱtoȱfunctionȱinȱthatȱrole.ȱȱHerȱdegreeȱwasȱmoreȱsuitableȱ
forȱaȱjobȱasȱaȱbioanalystȱorȱSASȱprogrammer.ȱHerȱfirstȱpositionȱafterȱgraduationȱwasȱworkingȱforȱXOMAȱasȱaȱstatisticalȱprogrammer.ȱȱSheȱattributedȱherȱmasterȇsȱ
degreeȱtoȱhelpingȱherȱobtainȱthisȱposition.ȱȱTheȱprogrammingȱexperienceȱthatȱsheȱhadȱinȱotherȱlanguagesȱalsoȱhelped.ȱȱThisȱisȱwhereȱsheȱ
learnedȱaboutȱtheȱinsȱandȱoutsȱofȱclinicalȱtrialsȱwhileȱperformingȱanalysisȱtoȱproduceȱtables,ȱlistingsȱandȱgraphs.ȱȱSheȱlearnedȱ
toȱstructureȱherȱworkȱandȱoptimizeȱprogrammingȱbyȱcreating ȱanalysisȱfilesȱandȱworkingȱmoreȱwithȱSASȱmacros.ȱȱSheȱattendedȱSASȱclassesȱandȱlearnedȱfromȱotherȱseniorȱSASȱprogrammersȱwhoȱworkedȱthereȱatȱXOMA.ȱȱȱ
SuzyȱthenȱmovedȱtoȱGenentechȱwhereȱsheȱworkedȱasȱaȱseniorȱSASȱprogrammer.ȱȱSheȱcontinuedȱtoȱlearnȱnewȱskillsȱfromȱSASȱ
conferencesȱandȱtheȱadditionalȱclassesȱsheȱtook.ȱȱHowever,ȱsheȱfoundȱthatȱtheȱbestȱwayȱforȱherȱtoȱlearnȱnewȱSASȱskillsȱwasȱtoȱ
workȱwithȱanotherȱexperiencedȱprogrammer.ȱȱSuzyȱisȱnowȱdoingȱworkȱinȱtheȱareaȱofȱelectronicȱsubmissionsȱandȱCaseȱReportȱ
Tabulations.ȱȱThisȱjobȱutilizesȱherȱknowledgeȱofȱclinicalȱdata,ȱSAS,ȱteachingȱskills,ȱandȱthe
programmingȱgroupsȱatȱGenentech.ȱȱSheȱenjoysȱbeingȱinvolvedȱwithȱprojectsȱwhereȱsheȱcanȱhelpȱtoȱcreateȱtheȱdocumentationȱ
forȱreviewersȱandȱdeliverȱaȱuserȱfriendlyȱsubmissionȱtoȱregulatoryȱagencies.ȱȱUponȱreflection,ȱthereȱwereȱtwoȱkeyȱmomentsȱforȱ
Suzyȱduringȱherȱcareerȱthatȱwasȱpivotal.ȱȱTheȱfirstȱmomentȱincludedȱtakingȱtheȱsummerȱinternȱjobȱatȱIBMȱandȱtheȱsecondȱwasȱ
gettingȱaȱmasterȇsȱdegreeȱinȱstatistics.ȱȱSheȱhasȱbeenȱfortunateȱtoȱhaveȱfoundȱaȱgreatȱjobȱthatȱcombinesȱherȱvariousȱinterestsȱandȱ
talents.ȱ ȱ ȱ TELECOMMUTEȱPROGRAMMERȱȬȱANGELAȱRINGELBERGȱ Communicating effectively while adapting to changes are key attributes to becoming a successful telecommuting SAS programmer.Angelaȱearnedȱaȱcomputerȱscienceȱdegreeȱinȱ1986ȱatȱtheȱUniversityȱofȱMobileȱAlabama.ȱȱSheȱdidȱnotȱprogramȱinȱSASȱduringȱ
school,ȱbutȱdidȱuseȱPL1ȱasȱtheȱprimaryȱprogrammingȱlanguage.ȱȱSheȱalsoȱdidȱassemblerȱprogrammingȱandȱdidȱnotȱapplyȱitȱ
towardsȱstatisticalȱmodelsȱsuchȱasȱinȱSAS.ȱȱWhenȱsheȱgraduated,ȱitȱwasȱdifficultȱtoȱgetȱaȱjobȱsinceȱsheȱwasȱcaughtȱinȱtheȱbindȱofȱ
notȱhavingȱtheȱnecessaryȱprerequisiteȱexperience.ȱȱAngelaȱhadȱwantedȱtoȱdoȱsomethingȱrelatedȱtoȱherȱtechnicalȱtrainingȱinȱ
computersȱsoȱsheȱstartedȱtoȱworkȱthroughȱtemporaryȱplacementȱagencies.ȱȱȱ
AngelaȱstartedȱoutȱasȱaȱdataȱentryȱclerkȱforȱMcDonaldȱDouglasȱinȱPhoenix,ȱArizona.ȱȱSheȱcontinuedȱtoȱbeȱshuffledȱaroundȱonȱ
variousȱtemporaryȱprojectsȱdoingȱdataȱentry.ȱȱTheseȱjobsȱwereȱnotȱwithinȱanyȱspecificȱcareerȱpathȱorȱindustryȱsinceȱtheȱ
placementsȱwereȱmoreȱentryȱlevel.ȱȱSheȱthenȱstartedȱtoȱworkȱthroughȱJeanȱSimpson,ȱaȱlocalȱsmallȱagencyȱin
whichȱplacedȱherȱatȱBootsȱPharmaceutical.ȱȱItȱwasȱanotherȱdataȱentryȱpositionȱbutȱafterȱthreeȱmonthsȱonȱtheȱjob,ȱsheȱ
progressedȱtoȱbecomeȱaȱSASȱprogrammer.ȱȱSheȱwasȱableȱtoȱaccomplishȱthisȱthroughȱtalkingȱtoȱvariousȱpeopleȱinȱtheȱ
organizationȱandȱinȱparticular,ȱtheȱbiostatisticsȱandȱdataȱmanagementȱ departments.ȱȱHerȱfirstȱintroductionȱtoȱSASȱprogrammingȱwasȱdoingȱeditȱchecks.ȱȱThisȱwasȱrelatedȱtoȱwhatȱsheȱwasȱdoingȱinȱthatȱitȱincludedȱalgorithmsȱwhichȱcheckȱforȱ
theȱaccuracyȱofȱtheȱdataȱwhichȱsheȱworkedȱwithȱduringȱherȱdataȱentryȱposition.ȱȱȱAlthoughȱsheȱdidȱnotȱworkȱonȱanalyzingȱtheȱ
dataȱstatistically,ȱtheȱdataȱmanagementȱtasksȱinȱconjunctionȱwithȱusingȱtheȱClintrialsȱdatabase,ȱgaveȱherȱaȱbetterȱ
understandingȱofȱclinicalȱtrialsȱdata.ȱȱHerȱprogrammingȱtasksȱexpandedȱintoȱprogrammingȱadȱhocȱrequestsȱforȱpatientȱlistingsȱ
andȱdataȱlistings.ȱȱMostȱofȱtheȱknowledgeȱwasȱobtainedȱonȱtheȱjobȱbutȱsheȱdidȱalsoȱtakeȱsomeȱ
classesȱfromȱSASȱInstituteȱwhichȱtaughtȱherȱmoreȱaboutȱSASȱmacrosȱandȱSAS/Graph.ȱȱAngelaȱstayedȱatȱBootsȱforȱfiveȱyearsȱandȱworkedȱherȱwayȱupȱtoȱ
becomingȱaȱsupervisor.ȱHerȱhusbandȱthenȱreceivedȱaȱtransferȱinȱhisȱjobȱtoȱSouthernȱCaliforniaȱatȱEdwardsȱAirȱForceȱBase.ȱȱItȱwasȱaboutȱtwoȱhours
ȱawayȱfromȱLosȱAngelesȱbutȱitȱwasȱaȱsmallerȱandȱmoreȱisolatedȱcommunity.ȱȱTheȱclosestȱbiotechȱcompanyȱwasȱAmgenȱbutȱthatȱ
8wouldȱhaveȱbeenȱaȱtwoȱandȱaȱhalfȱhourȱcommute,ȱsoȱthatȱwasȱoutȱofȱtheȱquestion.ȱȱEvenȱthoughȱsheȱwasȱinȱCalifornia,ȱAngelaȱ
receivedȱaȱrequestȱfromȱherȱformerȱemployerȱatȱBootsȱPharmaceuticalȱtoȱworkȱonȱaȱCANDAȱproject.ȱȱAtȱtheȱtime,ȱmanyȱ
companiesȱwereȱpreparingȱaȱcomputerȱaidedȱnewȱdrugȱapplicationȱsoȱthatȱtheȱFDAȱcouldȱreviewȱtheȱinformationȱthroughȱtheȱ
computer.ȱȱItȱwasȱaȱboonȱforȱprogrammersȱbecauseȱmanyȱcompaniesȱneededȱthisȱsolution.ȱȱTheȱproblemȱwasȱthatȱeachȱ
companyȱhadȱtheirȱownȱCANDAȱwhichȱmadeȱitȱchallengingȱforȱFDAȱreviewers.ȱȱThereȱwasȱaȱlargeȱlearningȱcurveȱforȱ
reviewersȱtoȱuseȱCANDAsȱbetweenȱdifferentȱcompanies.ȱȱAsȱaȱresult,ȱthisȱmethodȱisȱnoȱlongerȱusedȱbutȱitȱdidȱpresentȱanȱ
opportunityȱforȱAngelaȱtoȱworkȱremotelyȱatȱthatȱtime.ȱȱSheȱwasȱableȱtoȱuseȱherȱownȱPCȱtoȱlogȱintoȱtheȱremoteȱmachine.ȱȱTheȱ
employerȱevenȱgaveȱherȱSASȱlocallyȱtoAngelaȱbeganȱtoȱexploreȱotherȱtelecommutingȱprojectsȱthroughȱtheȱplacementȱfirmȱNovaTech.ȱȱSheȱworkedȱonȱprojectsȱforȱ
KnollȱPharmaceutical,ȱQuintiles,ȱNorvatis,ȱandȱNorfolkȱRailroadȱamongȱothers.ȱȱItȱworkedȱwellȱsinceȱsheȱwasȱableȱtoȱdoȱthisȱ
jobȱatȱherȱhome.ȱȱSheȱbeganȱtoȱmasterȱtheȱartȱofȱtelecommuting.ȱȱAngelaȱwasȱthenȱknownȱasȱtheȱqueenȱofȱemail.ȱȱThisȱwasȱherȱ
mainȱformȱofȱcommunicationȱinȱadditionȱtoȱtheȱphone.ȱȱSheȱworkedȱforȱNovatechȱforȱsixȱyears.ȱȱNearȱtheȱend,ȱsheȱpickedȱupȱaȱ
projectȱforȱaȱCROȱnamedȱPharmaNet.ȱȱSheȱwasȱaȱcontractorȱatȱfirstȱworkingȱremotelyȱsince
NewȱJersey.ȱȱTheyȱhadȱdeliveredȱtoȱherȱaȱmachineȱandȱaȱprinterȱwithȱallȱtheȱsecurityȱandȱsoftwareȱpreȬinstalled.ȱȱWithȱaȱDSLȱ
connection,ȱsheȱwasȱableȱtoȱlogȱonȱviaȱtheȱVPNȱandȱsheȱwasȱableȱtoȱdoȱworkȱfromȱthenȱon.ȱȱThereȱwereȱsomeȱ
challengesȱatȱfirstȱsinceȱsheȱhadȱtoȱsometimesȱwakeȱupȱearlyȱtoȱattendȱ6amȱmeetingsȱPacificȱTimeȱwhichȱwasȱ9amȱonȱtheȱeastȱcoast.ȱȱSheȱ
primarilyȱcommunicatedȱwithȱtheȱprojectȱmanagerȱandȱstatisticianȱremotely.ȱȱAllȱtheȱannotatedȱCRFȱwereȱscannedȱ
electronicallyȱandȱemailedȱtoȱAngela.ȱȱIfȱsheȱneededȱtoȱseeȱitȱonȱpaper,ȱsheȱcouldȱjustȱprintȱitȱout.ȱȱSheȱcontinuedȱtoȱdoȱsomeȱ
validationȱprogrammingȱbutȱtheȱmajorityȱofȱtheȱtimeȱwasȱspentȱdevelopingȱsummaryȱtables,ȱlistings,ȱandȱgraphs.ȱȱȱ
Mostȱofȱtheȱmeetingsȱwereȱdoneȱoverȱtheȱphone.ȱȱHowever,ȱAngelaȱdidȱalsoȱexperimentȱwithȱNetȱMeetingȱandȱMShowȱwhichȱ
allowedȱdesktopȱsharing.ȱȱEvenȱthoughȱsheȱstartedȱasȱaȱconsultant,ȱafterȱ5ȱmonths,ȱPharmaNetȱhiredȱherȱonȱasȱaȱpermanentȱ
employee.ȱȱȱAngelaȱhasȱaȱknackȱforȱworkingȱasȱaȱtelecommuter.ȱȱSheȱfeelsȱthatȱoneȱofȱtheȱprimaryȱskillsȱneededȱisȱtoȱhaveȱexcellentȱ
communicationȱskills.ȱȱThisȱcanȱmakeȱorȱbreakȱtheȱjobȱsinceȱeverythingȱhasȱtoȱbeȱcommunicatedȱthoughȱtheȱphoneȱorȱemail.ȱȱ
Sheȱalsoȱhasȱtheȱpassionȱforȱdoingȱthisȱsinceȱitȱgaveȱherȱbetterȱcontrolȱoverȱherȱscheduleȱandȱbetterȱqualityȱofȱlifeȱbyȱbeingȱ
closerȱtoȱherȱkids.ȱȱItȱalsoȱrequiresȱselfȬdisciplineȱsinceȱsheȱhasȱtoȱconstructȱherȱ
ownȱselfȱimposedȱ8ȱhourȱworkȱdaysȱwithoutȱsupervisorȱenforcement.ȱȱOneȱskillȱsheȱpickedȱupȱwasȱtoȱkeepȱtabsȱonȱherȱprojectsȱandȱcommunicateȱherȱstatusȱtoȱvariousȱteamȱ
membersȱconstantly.ȱȱThatȱway,ȱtheyȱwouldȱknowȱwhereȱsheȱisȱatȱandȱsendȱherȱtheȱrightȱamountȱofȱprojectsȱatȱtheȱright
Amongȱtheseȱskillsȱsets,ȱsheȱalsoȱhadȱtoȱgainȱaȱcertainȱlevelȱofȱtrustȱamongȱherȱcoȬworkersȱandȱsupervisor.ȱȱThisȱwasȱ
establishedȱatȱtheȱbeginningȱandȱworkedȱoutȱunderȱtheȱinitialȱcontract.ȱȱDuringȱthatȱtrialȱperiod,ȱifȱthingsȱdidnȇtȱworkȱout,ȱ
PharmaNetȱcouldȱeasilyȱendȱtheȱcontractȱ withoutȱanyȱlegalȱdifficulties.ȱȱȱAngelaȱhasȱaȱgoodȱcombinationȱofȱcommunicationȱskillsȱalongȱwithȱbeingȱveryȱadaptableȱinȱherȱwork.ȱȱSheȱmadeȱtheȱpivotalȱ
moveȱfromȱtheȱdataȱentryȱclerkȱintoȱSASȱprogrammingȱbyȱcommunicatingȱtoȱtheȱrightȱteam.ȱȱSheȱthenȱtransitionedȱandȱ
adaptedȱtoȱtheȱvariousȱprogrammingȱrequestsȱthatȱcameȱherȱwayȱevenȱthoughȱsheȱonlyȱhadȱexperienceȱinȱdataȱentry.ȱȱWhenȱ
sheȱwasȱrelocatedȱtoȱCaliforniaȱtoȱaȱsmallȱcommunity,ȱthisȱoutpostȱdidȱnotȱdeterȱherȱfromȱdoingȱherȱwork.ȱȱSheȱwasȱableȱtoȱ
adaptȱandȱreȬinventȱherselfȱasȱaȱtelecommutingȱprogrammer.ȱȱTheȱtechnologyȱinȱtelecommunicationsȱcombinedȱwithȱ
herȱtalentsȱenablesȱAngelaȱtoȱbeȱaȱproductiveȱandȱvaluableȱresourceȱnoȱmatterȱwhereȱsheȱisȱlocated.ȱ
ȱTheȱmoreȱexamplesȱyouȱseeȱonȱhowȱindividualsȱbecomeȱclinicalȱSASȱprogrammers,ȱtheȱmoreȱuniqueȱtheyȱappear.ȱȱTheȱstoriesȱ
ofȱtheȱfourȱindividualsȱinȱthisȱpaperȱareȱderivedȱfromȱaȱlongerȱsetȱ
ofȱstoriesȱwithinȱtheȱbookȱBecomingȱAȱClinicalȱTrialsȱProgrammer.ȱȱTheȱbookȱwillȱexploreȱinȱgreaterȱdetailȱcareerȱpathsȱalongȱwithȱtechnicalȱinformationȱbasedȱuponȱvaluableȱrealȱ
worldȱlessons.ȱȱThereȱisȱnoȱoneȱoptimalȱpathȱthatȱyouȱhaveȱtoȱtakeȱinȱorderȱtoȱbeȱsuccessfulȱinȱthisȱcareer.ȱȱTheȱstoriesȱsharedȱinȱ
thisȱpaperȱshowȱhowȱdiverseȱtheȱindividualsȱareȱinȱtheȱwayȱtheyȱtookȱtheirȱsteps.ȱȱEvenȱwithȱoneȱindividualȱsuchȱasȱSuzieȱQ,ȱȱ
manyȱturnsȱwereȱtakenȱinȱherȱcareerȱbeforeȱsettlingȱinȱthisȱwork.ȱȱPartȱofȱtheȱreasonȱwhyȱthisȱjobȱisȱsoȱdiverseȱisȱdueȱtoȱtheȱfactȱ
thatȱtheȱskillȱsetȱrequiredȱvariesȱasȱwell.ȱȱThereȱisȱtheȱdomainȱknowledgeȱthatȱisȱneededȱtoȱunderstandȱtheȱclinicalȱdata.ȱȱThisȱisȱ
combinedȱwithȱtheȱtechnicalȱskillsȱofȱaȱcomputerȱprogrammer.ȱȱItȱisȱtheȱcombinationȱofȱtheseȱskillsȱwhichȱcreatesȱsuchȱaȱ
diverseȱsetȱofȱrequirements.ȱȱThereȱisȱaȱcertainȱlevelȱofȱaptitudeȱthatȱisȱrequiredȱtoȱperform
ȱwell.ȱTheȱindividualȱalsoȱneedsȱtoȱbeȱinterestedȱandȱthereforeȱmaintainȱtheȱtenacityȱnecessaryȱtoȱovercomingȱchallengesȱinȱnavigatingȱthroughȱtheȱcareerȱpathȱofȱ
aȱSASȱprogrammerȱwithinȱtheȱBiotechȱandȱPharmaceuticalȱindustry.ȱ 9 ȱSASȱandȱallȱotherȱSASȱInstituteȱInc.ȱproductȱorȱserviceȱnamesȱareȱregisteredȱtrademarksȱorȱtrademarksȱofȱSASȱInstituteȱInc.ȱinȱ
theȱUSAȱandȱotherȱcountries.ȱ®ȱindicatesȱUSAȱregistration.ȱOtherȱbrandȱandȱproductȱnamesȱareȱregisteredȱtrademarksȱorȱtrademarksȱofȱtheirȱrespectiveȱcompanies.ȱ
ȱSyȱTruongȱisȱPresidentȱofȱMXIȱ(MetaȬXceed,ȱInc.)ȱȱTheyȱmayȱbeȱcontactedȱat:ȱ
ȱ