[PDF] Crisprs Creatures: Protecting Wildlife in the Age of Genomic Editing




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[PDF] Crisprs Creatures: Protecting Wildlife in the Age of Genomic Editing 41021_3qt79k515j0.pdf 1

CRISPR

Sadie Grunewald

Abstract

cum laude from Chicago-Kent College of Law in May

2 JOURNAL OF ENVIRONMENTAL LAW V37:1

. CRISPR's Predecessors ........................................................................y.. . Combining CRISPR With Gene Drives ...............................................

. Bene?ts ........................................................................y...........................

. Concerns ........................................................................y........................

. International Law ........................................................................y.........

. Federal Law ........................................................................y...................

. State Law ........................................................................y.......................

. Professional Self-Regulation ............................................................... . Federal Level Solutions ........................................................................y

. State Level Solutions ........................................................................y....

. Scienti?c Community Solutions ..........................................................

. Additional Issues ........................................................................y..........

2019 PROTECTING WILDLIFE IN ThE AGE OF GENOMIC EDITING3

See, e.g., Brendan Parent, Crispr Lit the Fire: Ethics Must Drive Regulation of , human Genome , 57

Gene Editing and the Rise of Designer Babies, 50

4 JOURNAL OF ENVIRONMENTAL LAW V37:1

Dr. Frankenstein, or: how I Learned to Stop Worrying and , 56 see also 2017 CRS Reportsupra note 1, Regents of the Univ. of Cal. v. Broad Inst., 903 F.3d. 1286, 1296-97 (Fed. Cir. 2018). see Gross, supra note 5, at 417-19; see also

Kane, supra note 3, at 305-06.

Synthetic Biology,

supra note 1, at 20 n.77. supra note 1, at 1-2; Gross, supra note 5, at 417, 420-21; Alison

Re-Framing Biotechnology Regulation, 72

Editing the Environment: Emerging Issues in Genetics and the , in

Gene Drives FAQ,

supra note 1, at 2.

Id. at 1 n.4.

See Irus Braverman, Gene Drives, Nature, Governance: An Ethnographic

2019 PROTECTING WILDLIFE IN ThE AGE OF GENOMIC EDITING5

in vivo method for mammalian genetic

Perspective, in

supra note 9. supra note 1, at 2; Danielle Simmons, Epigenetic In?uences and ,

See Sarah

Move over Cas9, CRISPR-Cas3 Might hold the Key to Solving the Antibiotics Crisis,

TechCrunch

(combination with Omar O. Abudayyeh et al., RNA Targeting With CRISPR-Cas13, 550 Scientists Unveil CRISPR-based Diagnostic Platform, supra note 9, at 13. supra note 9, at 3; Ian Tucker, Genetically Engineered Animals, In vivo refers to conducting an experiment with an organism in its natural habitat in vitro refers to experimentation in an arti?cial environment, such a test tube. Gross, supra note 5, at 423.

6 JOURNAL OF ENVIRONMENTAL LAW V37:1

CRISPR's Predecessors

The CRISPR toolkit is unique when compared to predecessor technol supra note 9, at 3 (quoting Professor Henry Greely of Stanford Law supra note 8, at 315.

See Gene Editing/

, Genetic Literacy Project, (Oct. 23, 2018), https://geneticliteracyproject.org/cate

Genome Editing with

, See What is CRISPR-Cas9, https://www.yourgenome.org/facts/ ; Parent, supra note 3 (discussing the downfalls of traditional gene editing supra note 1, at 2. supra note 5, at 420-21 (identifying previous techniques requiring "laborious

2019 PROTECTING WILDLIFE IN ThE AGE OF GENOMIC EDITING7

transforms the supra note 3, at 18-19; Elizabeth E. Pennisi, The CRISPR Craze, 341

See Cloning Fact Sheet,

Id. 26.

Animal Cloning, FDA (last updated Aug.

Chinese Scientists Clone Monkeys Using Method

,

Gene Editing Could Rewrite the GMO Debate,

supra note 3, at n.9; David Does CRISPR gene editing = GMO? Biotechnology Skeptics May Split on , See Kenneth Chang, These Foods Aren't Genetically Modi?ed but They Are 'Edited', (discussing the differences between con supra note 9, at 4; Peck, supra note 8, at 317.

8 JOURNAL OF ENVIRONMENTAL LAW V37:1

Combining CRISPR With Gene Drives

The CRISPR toolkit provides the possibility for scientists to use man Compare Cal. Code Regs. with Mich. Comp. Laws Ann. by means that are not possible under natural conditions or processes.") see also Warm?ash, supra note 28. supra note 9, at 4.

Gene Editing/CRISPR, supra note 21.

supra note 9, at 4; Peck, supra note 8, at 317; But see 2017 supra note 1, at 23 (doubting the ability of CRISPR-Cas9 to escape criticisms of conventional

The Promise and Peril of Gene Drives, The

See Brooke Borel, Genetic Engineering to Clash with Evolution, Id.

38.Id.

39.The Promise and Peril of Gene Drives, supra note 35; supra note

2019 PROTECTING WILDLIFE IN ThE AGE OF GENOMIC EDITING9

See Kevin M. Esvelt, Rules for Sculpting Ecosystems: Gene Drives and Responsive , in See Braverman II, supra note 12, at 63; Esvelt, supra note 40, at 25-27. See, e.g., Braverman II, supra note 12, at 65-69 (discussing gene drive application

Gene Drive Passes First Test in Mammals,

,

Engineering the Wild: Gene Drives and

, 56 See Ronald Sandler, Gene Drives and Species Conservation: An Ethical Analysis, in

Id. at 44-45.

See 2017 supra note 1, at 3; Braverman, supra note 9, at 4-5.

See Todd Kuiken, Vigilante

, in

US Agencies Tackle

, 547

10 JOURNAL OF ENVIRONMENTAL LAW V37:1

Bene?ts

As applied to wildlife editing, the CRISPR toolkit has the potential to

Building the Safe Genes Toolkit,

See Sandler, supra note 45, at 45 (noting support from the conservationist com

Animal Genome Editing,

The Promise and Peril of

, supra note 35 (conveying support from the Bill & Melinda Gates Foundation). See e.g., Amy Harmon, Open Season is Seen in Gene Editing of Animals, Welcome to the CRISPR Zoo, 531 supra note 40, at 23. See Braverman II, supra note 12, at 60 (pointing to the potential use of CRISPR

See e.g., Reardon, supra note 50 (describ

2019 PROTECTING WILDLIFE IN ThE AGE OF GENOMIC EDITING11

Gene Editing May Make Pigs Into

, See Managing public health risks at the human-animal-environment interface,

Saving Lives by Taking a One health

, Ctrs. for Disease Control & Prevention 3, Saving Lives by Taking a One health Approach, supra note 54. Id.

57.See Braverman II, supra note 12, at 65-66 (discussing Oxitec's application of gene

see also supra note 45, at 47.

Sustaining Life on Earth"].

Species and Climate Change, ICUN, https://www.iucn.org/resources/issues-briefs/ supra note 45, at 42; see, e.g., Conserve Elephants. They

12 JOURNAL OF ENVIRONMENTAL LAW V37:1

h old a Scienti?c Mirror Up to h umans, ] [hereinafter Conserve Elephants] (describ

Ecologists

, WMO Climate Statement: Past 4 Years Warmest on Record,

Rising Tides Will Sink Global Order,

See Braverman II, supra note 12, at 63 (quoting Esvelt's position that gene drives The Red List of Threatened Species,

Wildlife Conservation, World Wildlife Org.,

Program Data Report B-2017 Threatened & Endangered Species Conservation ,

2019 PROTECTING WILDLIFE IN ThE AGE OF GENOMIC EDITING13

See e.g., Sandler supra note 45, at 47.

See Conserve Elephants, supra note 60; Electronic Surveillance May Save the Rhino, supra note 45, at 46 (comparing the use of CRISPR for conservation

New Zealand's War

, supra note 45, at 46. The Promise and Peril of Gene Drives, supra note 35;

Feral Swine-Managing an Invasive Species,

Cruel Wildlife Control, PETA, https://www.peta.org/issues/wildlife/cruel-wild

Process of Elimination,

14 JOURNAL OF ENVIRONMENTAL LAW V37:1

See Sandler, supra note 45, at

Tweaking Genes to Save Species,

Nonpro?ts Sue to Stop 'Inhumane' Government Project to Sterilize , CNN (Sept. 25, 2018, 5:34 PM), https://www.cnn.com/2018/09/25/politics/ supra note 12, at 55. The Promise and Peril of Gene Drives, supra note 35; Sandler, supra note 45, at Exploring New Approaches, Predator Free 2050 Limited See e.g., Carmen G. Gonzalez & Sumudu Atapattu, International Environmental , 26 within rich nations because the Global North-South divide is used to re?ect the inequalities

2019 PROTECTING WILDLIFE IN ThE AGE OF GENOMIC EDITING15

across countries. See e.g., Gonzalez & Atapattu, supra note 80, at 230-35; Sumudu Atapattu, Climate Change, International Environmental Law Principles, and the North-South Divide,

Think Again: The

, supra note 80, at 230-35. supra 80, at 230-31; Environmental Crimes are on the Rise, , U.N. See, e.g., Headline Statements from the Summary for Policymakerssupra note 61.

Linking Biological and Cultural Diversity,

Sustaining

, supra note 59, at 6 ("Plants and animals are symbols of our world, preserved supra note 80, at 239-40. World heritage and Biodiversity, UNESCO, https://whc.unesco.org/en/biodiver Linking Biological and Cultural Diversity, supra note 85 ("Cultural practices depend See how Does Biodiversity Loss Affect Me and Everyone Else?, but see Gleb Raygorodetsky, ,

16 JOURNAL OF ENVIRONMENTAL LAW V37:1

Concerns

Human power over wildlife editing is accompanied with signi?cant risky. See e.g., Reardon, supra note 50, Harmon, supra note 50. supra note 50 (identifying a proposal to edit Koi ?sh through CRISPR , Melillo, supra note 3, at 760 (discussing the use of CRISPR for purely cosmetic

See Reardon, supra note 50.

David Shultz, Should We Bring Extinct Species Back From the Dead?, Id.

94.Id.

95.Id.

96.Id.

2019 PROTECTING WILDLIFE IN ThE AGE OF GENOMIC EDITING17

supra note 12, at 63-64; Esvelt, supra note 40, at 35 ("Conducting supra note 40, at 29. Id.

100.supra note 8, at 328; Esvelt, supra note 40, at 28-30.

supra note 40, at 29. See Molly Bond & Deborah Scott, In an Engineered World, Who Bene?ts from ,

Gene Editing/CRISPR, supra note 21 (describing

supra note 5, at 414 n.1. supra note 9, at 65 (identifying dangerous private interests at play with supra note 1, at 3-7 (discussing mar

18 JOURNAL OF ENVIRONMENTAL LAW V37:1

supra note 102; see generally Gonzalez & Atapattu, supra note 80, at UN Biodiversity Convention Agrees On Precautionary Approach , Gene Drive Should be a Nonpro?t Technology, Stat News

Gene Drives Should be a Nonpro?t Technology]

See Braverman, supra note 9, at 9.

See The Safety of CRISPR-Cas9 Gene Editing is Being Debated, supra note 9, at 11. supra note 3, at 19; The Safety of CRISPR- , supra note 109. See Barry R. Furrow, The CRISPR-Cas9 Tool of Gene Editing: Cheaper, Faster, , 26 Id.

2019 PROTECTING WILDLIFE IN ThE AGE OF GENOMIC EDITING19

Stop "Gene Spills" Before They happen, A New Possible Environmental Disaster: , supra note 9, at 55-56, 59.

Id. at 58.

Id. at 58-67.

Id. at 57-63.

supra note 1, at 25-26; Braverman, supra note 9, at 4 ("There has

Fast-spreading Genetic Mutations Pose Ecological

, supra note 45, at 47. supra note 40, at 25.

20 JOURNAL OF ENVIRONMENTAL LAW V37:1

Scientists Confront the Ghost of

, supra note 70. supra note 44, at 281. Id. 126.
only solution rather than address the fact that pollution stemming from poor indus supra see e.g., supra note 45, at 48-49.

2019 PROTECTING WILDLIFE IN ThE AGE OF GENOMIC EDITING21

See Melillo, supra note 3.

See e.g., Reardon, supra note 50; Harmon, supra note 50 (citing dissent for the tech The Safety of CRISPR Being Debated, supra note 109 (discussing concerns that CRISPR- See Borel, supra note 36; Kuiken, supra note 48, at 107 ("[G]ene drives are not supra note 70. See 2017 CRS Reportsupra note 1, at 31 (noting the U.S. Director of National supra note 50; Brian Farley, No, CRISPR Won't , The Promise and Peril of Gene Drives, supra note 35; Antonio Regalado, U.S. ,

See Callaway, supra note 48.

22 JOURNAL OF ENVIRONMENTAL LAW V37:1

de facto censor See Esvelt, supra note 40, at 26-27 (arguing that gene drives need to avoid bad see also Attacks on Science, See Silencing Science Tracker, Colum. L. Sch. Sabin Ctr. for Climate Change L., A Guide to Open Records Laws and Protections for Research Materials, Id.

138.Science as Speech, 102

See, e.g., Peck, supra note 8, at 319, 324-28.

Id. at 323.

Ten Years of Consumer Survey in USA,

2019 PROTECTING WILDLIFE IN ThE AGE OF GENOMIC EDITING23

See Sustaining Life on Earth, supra note 59, at 9 ("Education efforts on the impor supra note 9, at 10-11, 59 (noting inadequacy of current legal mecha supra supra note 106 (noting the various calls by civil society groups to supra note 9, at 1. See, e.g., Tracy Hester & Michael B. Gerrard, Going Negative: The Next horizon in , 32

24 JOURNAL OF ENVIRONMENTAL LAW V37:1

Nuisance,

Negligence,

Cause,

2019 PROTECTING WILDLIFE IN ThE AGE OF GENOMIC EDITING25

Trespass to Chattels,

Citizen Enforcement Under the Public Trust Doctrine, 32

See supra

supra note 28 (describing how common statutory phrases include "foreign DNA" supra note 9, at 7.

26 JOURNAL OF ENVIRONMENTAL LAW V37:1

International Law

Treaties can establish international obligations and norms to bind pacta sunt servanda, which states that "[e]very treaty in force is bind May 23, 1969, 1155 U.N.T.S. 331. While

Vienna Convention on the

, See Vienna Convention on the Law of Treaties, supra note 158, at art. 26. See Convention on Biological Diversity, June 5, 1992, 1760 U.N.T.S. 79 [hereinafter opened for signature Jan. 29, 2000, 2226 U.N.T.S. 208 (entered into force opened for signature Feb. 2. 2011, U.N.T.S. A-30619 entered into force Oct. 12, 2014), https://www.cbd.int/abs/doc/protocol/nagoya-protocol-en. supra note 9, at 6.

List of Parties,

What is CITES?, Convention on the Int'l Trade on Endangered Species

2019 PROTECTING WILDLIFE IN ThE AGE OF GENOMIC EDITING27

Id.

167.List of Contracting Parties,

how CITES Works, Convention on the Int'l Trade on Endangered

The CITES

, how CITES Works, supra note 168. Trump Should Rethink Leaving the Paris Agreement Before It's Too ,

28 JOURNAL OF ENVIRONMENTAL LAW V37:1

Trump has Of?cially Ruined Climate Change For Everyone, supra note 1, at 29; CBD, supra note 160, at 143. supra note 160, at art. 1, 2, 3, 15(1). supra note 161; Nagoya Protocol, supra note 161; https://treaties.un.org/doc/source/publications/thb/english.pdf [hereinafter supra note 175. supra note 161; Nagoya Protocol, supra note 161.

2019 PROTECTING WILDLIFE IN ThE AGE OF GENOMIC EDITING29

The CBD was signed by President

See Cartagena Protocol, supra note 161, at art. 6

See

International Agreements and US Law,

supra note 160, at art. 6, 15; What is a NBSAP?, supra note 160, at art. 6, 10; What is a NBSAP?, supra note 179.

See List of Parties, supra note 164.

See U.S. Const.

See List of Parties, supra note 164.

supra note 160, at art. 23 (identifying the Conference of Parties as the gov

COP14 - CP/MOP9 - NP/MOP3,

30 JOURNAL OF ENVIRONMENTAL LAW V37:1

supra note 160, at art. 25; Subsidiary Body on Scienti?c, Technical and (SBSTTA), See Bond & Scott, supra note 102 (noting how scientists in various sectors, bio Convention on Biological Diversity (CBD), ICUN, https://www.iucn.org/theme/ supra note 160, at pmbl. In-situ conservation refers to "the conservation of ecosystems and natural habitats Ex-situ conservation means the conservation of components of biological diversity supra note 160, at art. 2, supra note 162.

Id. at 2.

2019 PROTECTING WILDLIFE IN ThE AGE OF GENOMIC EDITING31

Id.

193.Id.

194.Id.

195.supra note 5, at 429-30.

See Gross, supra note

; but see Karrigan S. Börk & Rachael E. Salcido, Through the , 32 See Law and National Biodiversity Strategies and Action Plans, https://perma.cc/9E3K-J3V6] [hereinafter

Frequently

,

32 JOURNAL OF ENVIRONMENTAL LAW V37:1

FAQ Cartagena].

supra note 161, at art. 1, 2, 3(g), 17, 32.

Id. at art. 3(g).

See generally Cartagena Protocol, supra note 161, art. 3(g); Gross, supra note 5, at supra note 161, at art. 20; Information Sharing and , supra note 161, at art. 20. supra 161 at art. 20, 30; Information Sharing and the Biosafety , supra note 202.

2019 PROTECTING WILDLIFE IN ThE AGE OF GENOMIC EDITING33

supra note 161, at art. 6-9, 18.

Id. at

FAQ Cartagena, supra note 198.

Id.

209.Id.

210.supra note 161, at art. 1, 10(6), 11(8). See also FAQ Cartagena,

supra note 198. supra note 161, at art. 15-16.

Id. at art. 15, Annex III.

Id. at art. 16.

Id. at art. 26.

Socio-economic Considerations,

supra note 161, at art. 17.

34 JOURNAL OF ENVIRONMENTAL LAW V37:1

Barometer Rising: The Cartagena Protocol on Biosafety As A , 40 supra note 5, at 428-30. supra note 217, at 620. supra note 220, at Preamble, art.16; supra note 175, at 69. supra note 220, at art.

Id. at art. 5.

Id. at Preamble, art. 3, art. 5.

The Nagoya-Kuala Lumpur Supplementary Protocol on Liability and Redress to ,

2019 PROTECTING WILDLIFE IN ThE AGE OF GENOMIC EDITING35

UNEP Biodiversity Strategies, supra note 197, at 26; see e.g., Gonzalez & Atapattu, supra note 80, at 230-33 ("The Global North has generally prioritized the environmental

See Nagoya Protocol, supra note 161, at art. 1.

About the Nagoya Protocol,

See Nagoya Protocol, supra note 161, at art. 6, 17, 29, 30. Access to Genetic Resources: Article 6 of the Nagoya Protocol on Access and Bene?t- , IUCN, https://www.iucn.org/sites/dev/?les/import/downloads/short_paper___arti Id.

36 JOURNAL OF ENVIRONMENTAL LAW V37:1

support about 80% of the global biodiversity." supra note 161, at art. 6.

Id. at art. 5.

Id. at Annex.

Id. at art. 14-17; About the Nagoya Protocol, supra note 228. supra note 161, at art. 6-7, 12.

Id. at art. 21.

supra note 89. The Nagoya Protocol on Access, Bene?t-sharing, and Traditional Knowledge, supra note 161, at art. 12(3), 22(3), (4).

See Climate Change and the Environment,

In Focus: Climate Action by, and for, Women,

2019 PROTECTING WILDLIFE IN ThE AGE OF GENOMIC EDITING37

Sequencing the World, https://www.economist.com/sci [https://perma.cc/H2ES-8RGB]. Id.

244.See, e.g., Sequencing the World, supra note 242; Renard Sexton, Mineral Extraction

, supra note 244.

Sequencing the World, supra note 242.

Id.

248.supra note 80, 230-32.

The Safety of CRISPR Gene Editing is Being Debated, supra note 109.

38 JOURNAL OF ENVIRONMENTAL LAW V37:1

Federal Law

The U.S. federal government has several environmental laws and a reg , Animals' Legal Status, Animal Legal Defense Fund, https://aldf.org/issue/ani supra note 12, at 68 ("The biopolitical considerations of relative ; Church of Lukumi Bablu Aye, Inc. v. City of Hialeah, 508 U.S. 520, 543-544 (1993)

Animals'

, supra note 251; Richard L. Cupp Jr., Animals As More Than "Mere Things," But ,

2019 PROTECTING WILDLIFE IN ThE AGE OF GENOMIC EDITING39

see also supra note 1, at 9; Coordinated Framework for Regulation of , 51 Fed. Reg. 23302 (June 26, 1986). supra note 1, at 9. see also Coordinated Framework: how the , USDA-APHIS, https://www.aphis.usda.gov/ see also Pesticide Registration Manual: Chapter 12 - Applying , U.S. EPA, https://www.epa.gov/pesticide-registration/pesti Regulation of Biotechnology under TSCA and FIFRA, U.S. EPA, https://www. see also Modernizing the Regulatory , U.S. FDA, https://www.fda.gov/AnimalVeterinary/

40 JOURNAL OF ENVIRONMENTAL LAW V37:1

supra note 8, at 320-21. supra note 1, at 11 (outlining concerns of the Coordinated supra note 8, at 315 ("The new gen supra note 8, at 315, 324. supra note 8, at Improving , 2:57 PM EST), https://obamawhitehouse.archives.gov/blog/2015/07/02/improv supra note 1, at 2, 15; Braverman, supra note 9, at 7; Peck supra supra note 48, at 107. Secretary Perdue Issues USDA Statement on Plant Breeding , Id.

2019 PROTECTING WILDLIFE IN ThE AGE OF GENOMIC EDITING41

FDA's See e.g., Peck, supra note 8, at 321-22 (discussing how the other agencies have his supra note 1, at 26 (noting that the FDA distin see also Nick Stockton, FDA Wants to Regulate Edited , supra note 48, at 107. supra note 9, at 7.

Id. at 13.

supra note 8, at 315, 323-24 ("[T]he tangled web of agency oversight over

Id. §§ 1508.5, 1508.18.

42 JOURNAL OF ENVIRONMENTAL LAW V37:1

Id. § 1501.3.

Id. § 1508.9.

Id. §§ 1508.9, 1508.11.

See Freedom of

The National Environmental Policy Act: A Review of Its , 32 Id. 286.

2019 PROTECTING WILDLIFE IN ThE AGE OF GENOMIC EDITING43

Gene Editing/CRISPR, supra note 21; Kuiken, supra note 48, at 106-07. See sources cited supra note 48.

National security,

See e.g., San Luis Obispo

supra note 1, at 27-28.

44 JOURNAL OF ENVIRONMENTAL LAW V37:1

See What is CITES?, supra note 165.

Id. § 1532(6) (de?ning endangered

Id. § 1532(20) (de?ning threatened species as

Id. § 1533 (describing process for listing

§ 1536 (placing obligations on federal agencies to abide and providing penalties for id. § 1538 (prohibiting private parties' actions that take listed species and provid See Babbitt v. Sweet Home Chapter of Cmtys. for a Great Or., 515 U.S. 687, 696-708

2019 PROTECTING WILDLIFE IN ThE AGE OF GENOMIC EDITING45

State Law

State law could also provide protections against the negative risks of The Reauthorization of the Endangered Species Act,

Id. at 202-03.

Id. at 201-02.

See, e.g., Kathleen Hoke, What is Public health Law?, supra note 9, at 10 (noting that state police power has been See e.g., Hoke, supra note 305 (identifying that state police power has been used in see e.g., Hoke, supra note 305 (discussing preemption and

46 JOURNAL OF ENVIRONMENTAL LAW V37:1

See, e.g.,

State Action on Invasive Species,

supra note 12, at 68.

State Constitutional Right to hunt and Fish,

Fishing, hunting, and Wildlife,

State Constitutional Right to hunt and Fish, supra note 311.

2019 PROTECTING WILDLIFE IN ThE AGE OF GENOMIC EDITING47

Professional Self-Regulation

Professional self-regulation exists as a minimum level of protection

See State Biotech Statutes,

See e.g.,

See State Legislation Addressing Genetically-modi?ed Organisms,

See e.g., 50

, 0070 ?eld testing of , or environmental impact assessment of genetically modi?ed

See discussion supra Part

Cf. Joshua Busby & Johannes Urpelainen, Are States, Cities, and Companies Taking ,

48 JOURNAL OF ENVIRONMENTAL LAW V37:1

supra note 12, at 71 ("In place of state regulations, what seems to be supra note 12, at 64-65; Esvelt, supra note 40, at 27-30; Michael Private Governance and the New Private Advocacy, 32 supra note 320, 45.

Mayors,

, NPR accord [https://perma.cc/Y42S-X5WH]. supra note 5, at 432. supra note 12, at 65; see e.g., Gene Drives Should Be a Nonpro?t , supra note 107 (stating how this is a current concern among civil society groups

See discussion supra Part

supra note 40, at 35 (stating that "self-policing by the scienti?c community supra note 5, at 432.

2019 PROTECTING WILDLIFE IN ThE AGE OF GENOMIC EDITING49

DuPont Pioneer and Broad Institute Join Forces to Enable , See Furrow, supra note 112, at 45 (stating that "it is unlikely that we can rely on supra note 40, at 27-30 (discussing the public concerns and safe guidelines supra note 320, at 47 (discussing supra note 12, at 64-65; Esvelt, supra note 40, at 27-30; Gross, supra at 432.

50 JOURNAL OF ENVIRONMENTAL LAW V37:1

Federal Level Solutions

The United States should join the CBD and the two subsequent proto supra note 160, at art. 6, 15. See also Lacey Act of 1900, 16 U.S.C. §§ 3371-78 (2018)

See discussion supra Part supra note 9, at 13.

2019 PROTECTING WILDLIFE IN ThE AGE OF GENOMIC EDITING51

supra note 138, at 1237. See discussion supra Part supra note 9, at 14 (quoting Michael

52 JOURNAL OF ENVIRONMENTAL LAW V37:1

supra note 197, at 26 (referencing "the public partic supra note 8, at 316. supra note 9, at 10-11, 59 (noting that the CBD rejected various calls

2019 PROTECTING WILDLIFE IN ThE AGE OF GENOMIC EDITING53

State Level Solutions

Due to the intensity of Congress's polarization, the federal government See UNEP Biodiversity Strategies, supra note 198, at 26 (referencing "the principle supra note 80, at 234 ("environmental justice

54 JOURNAL OF ENVIRONMENTAL LAW V37:1

Scienti?c Community Solutions

The private and public scienti?c communities should continue to self-po

See discussion supra Part

supra note 320, at 45-47.

2019 PROTECTING WILDLIFE IN ThE AGE OF GENOMIC EDITING55

Additional Issues

This Article aspires to lay the foundation for further exploration into

See e.g., Global Biodiversity Outlook 4,

Science Bene?ts from Diversity,

,

56 JOURNAL OF ENVIRONMENTAL LAW V37:1

See Stuart M. Speiser, Charles F. Krause, Alfred W. Gans, Wild and dangerous domestic animals, , 7 U.S. Climate Change Litigation, Climate Change Litigation Database

New Green advocates: Climate-Change Lawsuits,

See Kuzma & Rawls, supra note 44, at 281-85.

2019 PROTECTING WILDLIFE IN ThE AGE OF GENOMIC EDITING57


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