may provide substantial improvement to cancer therapy Keywords: Cell cycle checkpoint, Cancer drug, DNA damage, Mitosis, Chk1, Wee1, Spindle assembly
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10 sept 2021 · It is often assumed that cancer cells undergo uncontrolled cell cycle progres- sion and that most, if not all, cell cycle checkpoints need
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e g DNA damage in G1 or G2, lack of nutrients • incomplete DNA replication • incomplete establishment of mitotic apparatus Cell-Cycle Checkpoints Page 46
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