Types of Disinfectant
Oxidizing disinfectants include the halogens chlorine
Guidance Notes on Safe Use of Chemical Disinfectants
3 CHEMICAL DISINFECTANTS CLASSES. 3. 3.1 Alcohols. 3. 3.2 Aldehydes. 3. 3.3 Chlorine Compounds. 3. 3.4 Iodine Compounds. 3. 3.5 Phenolics.
Guideline for Disinfection and Sterilization in Healthcare Facilities
Even though the OSHA standard does not specify the type of disinfectant or procedure the OSHA original compliance document 269 suggested that a germicide
Disinfection 101
For a comparison of microorganisms and their susceptibility to a various disinfectant chemical classes see 'The Antimicrobial Spectrum of Disinfectants' table
Disinfectants and sanitizers for use on food contact surfaces
disinfecting and sanitizing food contact surfaces. This document is intended for food safety inspectors and auditors who may review the types and usage of.
Disinfectants are characterized into 3 activity levels according to
The EPA approves chemical germicides used in this procedure in the US as "hospital disinfectants" or "sanitizers." Commonly used classes of chemical germicides
Evaluation of Cleaners Sanitizers
https://www.health.state.mn.us/communities/environment/risk/docs/guidance/cleaners.pdf
Wastewater Technology Fact Sheet: Chlorine Disinfection
domestic wastewater and the types of human Chlorine is the most widely used disinfectant for ... alternative disinfectants include ozonation and.
Information Paper 3.8. 1 A Citizen Monitors Guide to Disinfectants
29-Jun-2007 There are various types of disinfectants including
Laboratory Disinfectants
Do not use 70% ethanol to clean a Class II Type A recirculating biosafety cabinet. The vapors from ethanol are flammable and the lower explosive limit (LEL)
List of Disinfectants - Princeton University
List of Disinfectants Disinfectants How they Work Advantages Disadvantages Hazards Phenolics p Examples: Wescodyne Carbolic Soap Breaks down proteins through roteolysis • Active against vegetative bacteria and lipid-containing viruses • Not effective against spores • Variable activity against non-lipid containing viruses
Types of Disinfectant
Types of Disinfectant 0006 Disinfectants can be split into two broad groups oxidizing and nonoxidizing Oxidizing disinfectants include the halogens chlorine iodine bromine and chlorine dioxide and oxygen-releasing materials such as peracetic acid and hydrogen peroxide Nonoxidizing disinfectants are as follows: quaternary
Searches related to types of disinfectants PDF
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What are the different types of disinfectants?
There are multiple types of disinfectants, including but not limited to air disinfectants, alcohols, and oxidizing agents. Air disinfectants are typically chemical substances capable of disinfecting microorganisms suspended in the air. Alcohols, usually ethanol or isopropanol, are sometimes used as a disinfectant, but more often as an antiseptic.
Which chlorine disinfectant is most commonly used?
Hypochlorites, the most widely used of the chlorine disinfectants, are available as liquid (e.g., sodium hypochlorite) or solid (e.g., calcium hypochlorite). The most prevalent chlorine products in the United States are aqueous solutions of 5.25%–6.15% sodium hypochlorite (see glossary), usually called household bleach.
What is the role of alcohol in disinfection?
Alcohols, usually ethanol or isopropanol, are sometimes used as a disinfectant, but more often as an antiseptic. Oxidizing agents act by oxidizing the cell membrane of microorganisms, which results in a loss of structure and leads to cell lysis and death.
Are phenolic disinfectants FDA approved?
Phenolics are not FDA-cleared as high-level disinfectants for use with semicritical items but could be used to preclean or decontaminate critical and semicritical devices before terminal sterilization or high-level disinfection.
Types of Disinfectant
J Fisher, Diversey Ltd, Riddings, UK
This article is reproduced fromEncyclopaedia of Food Science, FoodTechnologyandNutrition, Copyright 1993, Academic Press.Background
0001In food factories, the detergent stage is normally
followed by a disinfecting stage. The detergent stage is required to remove all the soil, leaving a chemically clean surface. The disinfectant stage is used as an extra guarantee of cleanliness and to prevent recon- tamination in some cases. It does not compensate for a bad detergent stage or badly designed process or cleaning equipment.Disinfection0002The definition of disinfection taken from BS5283
(1986) states'The destruction of microorganisms, but not usually bacterial spores. It does not neces- sarily kill all microorganisms but reduces them to a level acceptable for a defined purpose, for example a level which is harmful neither to health nor to the quality of perishable goods.'The acceptable level of microbial contamination on a surface or piece of equipment has to be determined; obviously, no patho- gens should be found. (SeeSpoilage: Bacterial Spoil-age; Molds in Spoilage; Yeasts in Spoilage.)0003The state of sterility is defined as free from all living
microorganisms. This is not achievable in the food factory by using acceptable chemicals ('acceptable' meaning safe for humans, plant materials and prod- ucts).0004Disinfectants are used after the detergent applica-
tion in cleaning-in-place (CIP) operations where the term'terminal sterilant'may be used. They are also used after hand cleaning. Equipment should be left in a soak bath until it is ready to be used, thus ensuring that it remains free from recontamination.0005There are a wide range of disinfectants available.The choice of disinfectant depends on the user's
requirements, the type of processing and cleaning equipment, the method of use, and, to some extent, the personal preference of the user.Types of Disinfectant
0006Disinfectants can be split into two broad groups,
oxidizing and nonoxidizing. Oxidizing disinfectants include the halogens, chlorine, iodine, bromine, and chlorine dioxide, and oxygen-releasing materials such as peracetic acid and hydrogen peroxide. Nonoxidizing disinfectants are as follows: quaternary ammonium compounds, amphoterics, biguanides, and acid anionics.Physical and Chemical PropertiesOxidizing Disinfectants
0007HalogensChlorine and iodine have been used as
terminal disinfectants for many years. More recently, bromine and chlorine dioxide have been introduced.0008ChlorineChlorine was first used as a gas for fumi-
gation in hospitals in 1791, but this application has one obvious drawback-chlorine gas is toxic. Active chlorine is available from two types of material: 1.0009Inorganic compounds containing hypochlorite
ions either as a liquid, e.g., sodium hypochlorite (NaOCl), or as a powder, e.g., chlorinated triso- dium phosphateððNa3
PO 4 :11H 2 OÞ 4NaOCl,NaClÞ:
2.0010Powdered organic chlorine release agents, e.g.,
trichloroisocyanurate (Figure 1). In solution, both types hydrolyze to produce hypo- chlorous acid and/or hypochlorite ions, depending on the pH.Acid Alkaline
Cl 2ÐHOCl
ÐOCl?
Chlorine gas Hypochlorous acid Hypochlorite ion
In the food industry, sodium hypochlorite is used as a general-purpose disinfectant. It is most stable in a slightly alkaline solution, and it is for this reason that the concentrate is supplied stabilized with sodium hydrocide at a pH of up to 12. An in-use solution of between 50 and 300p.p.m. will have a pH between 7 CI CI CIN NN C CC O OOfig0001Figure 1Trichloroisocyanuricacid.Reproducedfrom Cleaning Procedures in the Factory: Types of Disinfectant,Encyclopaediaof Food Science, Food Technology and Nutrition, Macrae R, RobinsonRK and Sadler MJ (eds), 1993, Academic Press.
!(CLEANING PROCEDURES IN THE FACTORY/Types of Disinfectant the solution is less stable. Below pH 5.0, chlorine gas will be produced.0011Applications for sodium hypochlorite in the food
industries are CIP, soak, and spray. Sodium hypo- chlorite has many advantages: it is nonfoaming; it is not affected by water hardness; it does not leave an active residue, and it has a wide antimicrobial spec- trum, which includes activity against bacterial spores and viruses. It is also fast-acting and cheap.0012However, it also has numerous disadvantages: it
can be corrosive to a wide range of components, including stainless steel; it is irritating to the skin and eyes; the in-use solution is unstable; it is inacti- vated by organic materials, and it may give rise to taint problems.0013Chlorine dioxideChlorine dioxide (ClO
2 ) is an un- stable and toxic gas that is soluble in water. When chlorine dioxide is generated in solution, as shown below, it is a very effective water disinfectant at point of use.5NaClO
2þ4HClÐ4ClO
2þ5NaClþ2H
2 O: Chlorine dioxide at use concentrations (0.5-1p.p.m.) overcomes some of the disadvantages of hypochlorite in that it is nontainting, noncorrosive, and nontoxic.Its sole use at present is in water disinfection.
0014IodineIodine itself is not very soluble in water, and
the vapor is irritating to the eyes, making it difficult to handle. Iodine is a very reactive element, and it is this reactivity that makes it a good disinfectant.0015Iodine compounds used in the food industry con-
tain iodine complexed with polyvinylpyrrolidone and other surface active agents, usually in an acid solu- tion. These are known as iodophors and were first introduced in 1949.0016The complexes formed between iodine and carrier
molecule are water-soluble and overcome the hand- ling difficulties of iodine whilst retaining the disin- fecting power. On dilution, the iodophors release iodine gradually, and it is the free iodine that acts as the disinfecting agent. The optimum pH for microbial activity is pH 5.0.Acid Alkaline
I 2ÐHOIÐOI
ÐIO
Greatest Some Inactive Inactive
activity activityThe surface-active agents provide better wetting
and organic soil penetration, thus making iodophors less affected by soil than hypochlorite. The choice of surface-active agent may lead to foam generation in applications such as CIP.0017Iodophors have a broad antimicrobial spectrum
that is similar to hypochlorite, although they are less active against bacterial spores. In common with sodium hypochlorite, they are fast-acting but are more expensive. Iodophors are used in soak baths and spray application at up to 10p.p.m. available iodine. In solution, iodophors are yellow-brown in color. This color can be an advantage: in a soak bath application, the color indicates the presence of iodine; the in-use solutions are unstable, so that as the iodine dissipates, the solution will become colorless.0018Staining may be a problem, especially with some
plastics, and this may also result in taint problems. Iodophors can be corrosive; it is therefore necessary to ensure that the correct dilution is used; otherwise, damage to plant and personnel may occur.0019BromineBromine itself is not used as a disinfectant,
mainly because of its handling difficulties. Bromo- chlorodimethylhydantoin is supplied as a powder or a solid. In solution, it releases hypobromous and hypochlorous acids.0020Oxygen-releasing compounds0020
Peracetic acidPeracetic acid was introduced in
1955. The material is supplied as an equilibrium mix-
ture: CH 3Cð¼¼OÞOOHþH
2OÐCH
3Cð¼¼OÞOH
Peracetic acid Water Acetic acid
þH 2 O 2Hydrogen peroxide
It is soluble in water and is completely biodegradable, breaking down to harmless products: 2CH 3Cð¼¼OÞOOH!2CH
3Cð¼¼OÞOHþO
2 As supplied, peracetic acid is corrosive and has a very irritating smell, similar to vinegar; because of these properties, it is unpleasant to handle, and manual use is not recommended. It is suitable for CIP, as it is nonfoaming.0021Peracetic acid is a highly reactive material. As an
in-use solution, it is not very stable and will react with organic materials. Peracetic acid may attack plant materials, such as rubber gaskets, and at higher con- centrations, corrosion may be a problem.0022Peracetic acid has a wide antimicrobial spectrum,
which includes bacterial spores and viruses. This ac- tivity is fast and is maintained at temperatures lower than ambient.0023Hydrogen peroxideHydrogen peroxide (H
2 O 2 was introduced asadisinfectant in 1887. Itis supplied in solution, which has a tendency to decompose: CLEANING PROCEDURES IN THE FACTORY/Types of Disinfectant1383 2H 2 O 2 !2H 2OþO
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