[PDF] alcohol metabolism biochemistry

Alcohol is metabolized by several processes or pathways. The most common of these pathways involves two enzymes—alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH). These enzymes help break apart the alcohol molecule, making it possible to eliminate it from the body.
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  • What is the process of alcohol metabolism?

    Most alcohol is broken down, or metabolised, by an enzyme in your liver cells known as alcohol dehydrogenase (ADH). ADH breaks down alcohol into acetaldehyde, and then another enzyme, aldehyde dehydrogenase (ALDH), rapidly breaks down acetaldehyde into acetate.

  • What are the three steps of metabolism of alcohol?

    The first three steps of the reaction pathways lead from ethanol to acetaldehyde to acetic acid to acetyl-CoA. Once acetyl-CoA is formed, it is free to enter directly into the citric acid cycle.

  • What is the metabolic pathway for alcohol in the liver?

    In the liver, alcohol is metabolized by the oxidative and non-oxidative pathway. In the oxidative pathway, the major pathway of alcohol digestion, alcohol is oxidized to acetaldehyde by various enzymes including alcohol dehydrogenase (ADH), cytochrome P450 2E1 (CYP2E1), and catalase.
  • NADH promotes alcohol metabolism and prevents liver injury caused by alcohol. NADH alleviates the abnormal lipid metabolism in acute alcoholic liver damage. NADH can be used as an agent to protect and recover liver function damage.
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The biochemistry of alcohol metabolism â•? A brief review

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Activities of human alcohol dehydrogenases in the metabolic

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biochemical and genetic studies on enzymes of alcohol metabolism

This paper describes the biochemical and genetic status of the two key enzymes of ethanol metabolism (alcohol dehydrogenase and aldehyde dehydrogenase) in