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Drug Calculations

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Remember that for intravenous infusion sometimes you are asked to calculate volume



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DRUG-CALCS _20220927 Page 1 of 5

DRUG CALCULATIONS

© Student Learning Support Service, 2022

slss@flinders.edu.au students.flinders.edu.au/slss Identify what type of drug calculation and as a first step, use common sense to estimate a rough

answer. In many cases, drawing a picture that visually represents the problem is often a helpful strategy.

Remember that a formula often used for working out how many tablets to take or for a drug taken orally or injected is:

VOLUME REQUIRED =

STRENGTH REQUIRED (SR)

x

VOLUME OF STOCK

STOCK STRENGTH (SS) 1

Remember that a formula often used to work out the number of drops per minute delivered by an intravenous infusion is:

DRIP RATE (DPM) =

VOLUME (mL) x DROPS/mL

TIME (h) x 60

Remember that for intravenous infusion, sometimes you are asked to calculate volume, time, or rate, and the following formulae can be useful:

VOLUME (mL) =RATE (mL/h) x TIME (h)

RATE

VOLUME (mL)

TIME =

VOLUME (mL)

TIME (h)

RATE (mL/h)

After applying the formula (if relevant), or calculating an exact answer using common sense, go back and check: is your final answer close to your initial estimate? If not, why not?

EXAMPLE 1: DRUG MADE UP FROM STOCK SOLUTION

This example illustrates how to work out injections or orally taken drugs made up from stock solution

- for example, working out how many mLs to inject when the drug is in a stock solution.

QUESTION: A patient is ordered 70 mg of pethidine. Find the volume required if the stock solution contains 10g

of pethidine per 200mL.

TO SOLVE: We'll be using this formula:

VOLUME REQUIRED =

STRENGTH REQUIRED (SR)

x VOLUME OF STOCK

STOCK STRENGTH (SS) 1

1. Note down the strength of medication the patient needs and the stock strength:

Strength Required is 70 mg, Stock Strength is 10g in 200 mL At this point our rough answer is - More than 1 mL and a lot less than 200mL.

2. Since you need units to be the same, convert 10 g to mg by multiplying by 1000.

e.g. 1000mg x 10 = 10,000mg (10,000mg = 10g)

3. Now put the values into the above for.

Note that 70mg (what the patient needs) is a very small part of

10,000mg - so expect your

answer in mL to be much less than 200mL ANSWER: Based on the above, your answer = 1.4mL VOLUME REQUIRED = 70
x 200
mL = 14 14 mL = 1.4mL 10 1 10 10

HOW TO SOLVE DRUG CALCULATIONS

TIP: An easy way to

remember this formula is

SUNRISE (SR)

SUNSET (SS)

NOTE: DPM stands for drops per minute CONVERSION TIP:

X 1,000

g mg

÷ 1,000

VISUAL

REPRESENTATION

10,000mg

PETHIDINE

200mL
solution

DRUG-CALCS _20220927 Page 2 of 5

DRUG CALCULATIONS

© Student Learning Support Service, 2022

slss@flinders.edu.au students.flinders.edu.au/slss

EXAMPLE 2: INTRAVENOUS INFUSION

This example indicates how many mLs to give in a certain time, and how many drops per minute a patient will receive. QUESTION: A teenager who is badly dehydrated is to receive 1.5 L over

10 hours of rehydration fluid by IV infusion. The giving set delivers 20

drops/mL. Calculate the drip rate. TO SOLVE: We'll be using this formula - remember that DPR stands for 'drops per minute'

DRIP RATE (DPM)

VOLUME (mL) x DROPS/mL

TIME (h) x 60

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