[PDF] Ephédra - Antidoping Schweiz - Chirurgie

How does ephedrine work?

Ephedrine is administered by intravenous boluses. Redosing usually requires increased doses to offset the development of tachyphylaxis, which is attributed to the depletion of catecholamine stores. Ephedrine promotes modest short-term weight loss, specifically fat loss, but its long-term effects are unknown.

Which enantiomers are ephedrine?

By convention, the pair of enantiomers with the stereochemistry (1 R ,2 S) and (1 S ,2 R) is designated ephedrine, while the pair of enantiomers with the stereochemistry (1 R ,2 R) and (1 S ,2 S) is called pseudoephedrine. Ephedrine is a substituted amphetamine and a structural methamphetamine analogue.

How much ephedrine is produced in China?

Raw materials for the manufacture of ephedrine and traditional Chinese medicines are produced in China on a large scale. As of 2007, companies produced for export US$13 million worth of ephedrine from 30,000 tons of ephedra annually, or about ten times the amount used in traditional Chinese medicine.

Does ephedrine reduce motion sickness?

Ephedrine may decrease motion sickness, but it has mainly been used to decrease the sedating effects of other medications used for motion sickness. Ephedrine is also found to have quick and long-lasting responsiveness in congenital myasthenic syndrome in early childhood and also even in the adults with a novel COLQ mutation.