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Le pa- ramètre vitesse d'absorption inter- vient surtout lors des premières prises du médicament; à l'état d'équilibre les aliments la modifient moins signi-.
Les interactions entre les aliments et les médicaments dans la
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Interactions des médicaments avec l’alimentation
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Nutrient-Drug Interactions and Food - Extension
May 1 2013 · Drug-nutrient interactions involve changes to a drug caused by a nutrient or changes to a nutrient as a result of the drug Food-drug interactions is a broader term that describes the effects of a drug on nutritional status Each of these interactions may lead to many complications Table 1 summarizes several possible interactions of drugs with
Searches related to interactions médicaments aliments PDF
à la prise de médicaments 235 ANOREXIE ET PERTE D'APPÉTIT 236 COUTE PSEUDO-MEMBRANEUSE 240 CONSTIPATION 242 DIARRHÉE 249 GLYCÉMIE (augmente) 256 GLYCÉMIE (diminue) 260 GOÛT (altération du) 263 IRRITATIONS GASTRO-INTESTINALES /TROUBLES DIGESTIFS / CRAMPES ABDOMINALES / DOULEURS ÉPIGASTRIQUES ET GASTRO-INTESTINALES 269 LIPÉMIE
Quels sont les différents types d’interactions aliments-Médica-ments ?
Le tableau énumère les interactions aliments-médica- ments les plus classiques dont le re- tentissement clinique est probable. Certains médicaments dont l’action se limite au tube digestif doivent être aussi peu résorbés que possible et font donc l’objet de recommandations particulières (ex: anti-acides, enzymes digestives, antifongiques locaux).
Quels sont les effets des médicaments avec l’alimentation prise d’aliments ?
Interactions des médicaments avec l’alimentation prise d’aliments. Ces interactions sont cliniquement significatives pour les médicaments à marge thérapeutique étroite, dont il importe que les concentrations moyennes soient confinées dans une fourchette bien définie (théophylline, phénytoïne, ci- closporine, etc.).
Comment les aliments affectent-ils l'absorption des médicaments ?
Les aliments peuvent augmenter, retarder ou réduire l'absorption des médicaments. Les aliments altèrent l'absorption de nombreux antibiotiques. Ils peuvent modifier le métabolisme des médicaments; p. ex., les régimes à forte teneur en protéines peuvent accélérer le métabolisme de certains médicaments en stimulant le cytochrome P-450.
Quels sont les facteurs qui influencent les interactions entre les aliments ?
Autres facteurs Dose et quantité d’aliments: Les interactions dépendent de la dose ad- ministrée et de la quantité d’aliments qui se rencontrent dans le tube diges- tif. Au-delà d’une certaine dose, selon le mécanisme impliqué, une interac- tion peut devenir insignifiante sur le plan clinique.
Fact Sheet No.
9.361 Food and Nutrition Series|Health
by L. Bellows and R. Moore* ?e complex interaction between food, nutrients, and drugs, make it di?cult to accurately determine the exact e?ects of these relationships in the body. A drug is de?ned as a substance used in the diagnosis, treatment, or prevention of a disease, or component of a medication. ?ere are many dramatic results and problems that may be caused by food- drug, drug-drug, and alcohol-food-drug interactions, and these vary from person to person. Drug-nutrient interactions involve changes to a drug caused by a nutrient, or changes to a nutrient as a result of the drug.Food-drug interactions is a broader term that
describes the e?ects of a drug on nutritional status. Each of these interactions may lead to many complications. Table 1 summarizes several possible interactions of drugs with foods, nutrients, supplements, or other drugs, which may produce unexpected side-e?ects or cause additional health problems.Effects of Food on Drug
Intake
Drug Absorption: Food or nutrients in the
stomach or intestine may act to reduce the absorption of a drug by delaying digestion, binding to minerals found in the food, or adhering to food particles. In other cases, the food may promote drug absorption.Drug Breakdown: Food may act to
enhance or inhibit the metabolism of certain drugs in the body. Drug Excretion: Food and nutrients may act to alter the reabsorption and excretion of drugs from the kidney.Other Actions: Certain food components
can lead to the enhancement or opposition of the e?ects of some drugs. Some examples of food and constituents found in food include: vitamins, minerals, fat, proteins, ca?eine, or alcohol.Quick Facts
L. Bellows, Colorado State University Extension food and nutrition specialist and assistant professor; R. Moore, graduate student. 9/2013Nutrient-Drug Interactions and Food
Effects of Drugs on Food
and NutritionNutrient Absorption: Certain drugs
may increase, decrease, or prevent nutrient absorption in the gut.Nutrient Breakdown: Drugs may speed up
the metabolism of certain nutrients, resulting in higher dietary requirements of that particular nutrient.Nutrient Excretion: Drugs can increase or
decrease the urinary excretion of nutrients.Side Effects of Drugs and Other Medications
Taste and Smell Alterations: Some drugs
may alter one's ability to taste and smell certain foods. Food intake may be a?ected due to alteration of taste sensation, reduced acuity to taste, or undesirable a?ertaste.Gastrointestinal (GI) E?ects: Some drugs
can cause irritation to the digestive tract that includes stomach upset, nausea, vomiting, diarrhea, constipation, ulcers, and gastric bleeding. Some drugs may alter gastric acidity and damage mucosal surfaces leading to decreased nutrient absorption.Appetite Changes: Alterations in appetite
may include suppression or stimulation of hunger leading to weight loss or weight gain.Organ Toxicity: Since many drugs must
pass through the liver and kidney upon excretion, hepatotoxicity (liver damage) and nephrotoxicity (kidney damage) are of primary concern.Metabolic E?ects: Some drugs may a?ect
blood glucose levels by stimulating the production of glucose or inhibiting its uptake.Other drugs may inhibit insulin secretion,
decrease insulin sensitivity, or increase insulin clearance from the blood. ?is may lead to conditions known as hyperglycemia (high blood glucose), hypoglycemia (low blood glucose), or diabetes. Other medications may lead to abnormal lipid levels, causing elevated cholesterol or triglycerides.Table 1. Food, Nutrient, and Drug Interactions.
Condition Drug Use Interactions/Guidelines Examples 1Allergies
Food:Exception
Other drugs
Avoid alcohol
Arthritis Food:
and PainCaffeine:
Avoid alcohol
Food:Caffeine
Supplements
Avoid alcohol
Food:Caffeine
Avoid alcohol
FoodAvoid alcohol
Asthma Food:
Caffeine:
Avoid alcohol
Cardio-Food:
vascularDisorders
Table 1. Food and Drug Interactions. (continued)
Condition Drug Use Interactions/Guidelines Examples 1Cardio-Food
vascularDisorders
Other drugs
Avoid alcohol
Food:Supplements:
Avoid alcohol
Food:Avoid alcohol
Food: Food:Supplements
Avoid alcohol
Food:Supplements
Other drugs
Infections General Guidelines:
Food:Supplements
Table 1. Food and Drug Interactions. (continued)
Condition DrugUse Interactions/Guidelines Examples 1Infections
FoodCaffeine
Food FoodExceptions
FoodAvoid alcohol
Food FoodAvoid alcohol
FoodAvoid alcohol
MoodFood
Disorders
Avoid alcohol
FoodCaffeine
Supplements
Avoid alcohol
Table 1. Food and Drug Interactions. (continued)
Condition DrugUse Interactions/Guidelines Examples 1Mood Food
Disorders
Avoid alcohol
Food FoodStomach
FoodCaffeine
Avoid alcohol
Seizures Food
Avoid alcohol
References
Avoid Food-Drug Interactions: A Guide
from the National ConsumersLeague and U.S. Food and Drug
Administration. Available at http://
www.fda.gov/downloads/Drugs/ResourcesForYou/Consumers/
BuyingUsingMedicineSafely/
EnsuringSafeUseofMedicine/
GeneralUseofMedicine/UCM229033.
pdf last accessed on May 1, 2013.Mahan, L.K., Escott-Stump, S., Raymond,
J.L., & Krause, M.V. (2012). Krause's
Food & the Nutrition Care Process. St.
Louis, MO: Elsevier/Saunders.
Pronsky, Zm. Food Medication
Interactions. 15th Edition. Birchrunville,
Pa: 2008.
U.S. Food and Drug Administration
(FDA).For Consumers: AvoidingDrug Interactions. Available at
http://www.fda.gov/ForConsumers/ConsumerUpdates/ucm096386.htm last
accessed on May 1, 2013.U.S. Food and Drug Administration
(FDA). Council on Family Health.Drug interactions: What You Should
Know. Available at http://www.fda.gov/
downloads/Drugs/ResourcesForYou/UCM163355.pdf last accessed on May
1, 2013.
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