La Ricine une arme biologique : « Info ou In…tox ?! »
Etes-vous de la génération « huile de ricin » ? En réalité ce n'est pas loin de la vérité
CONDUITE A TENIR LORS DUN ÉVÉNEMENT BIOLOGIQUE OU
07?/05?/2019 La fabrication et la volonté des terroristes à utiliser des armes ... tutoriels de fabrication d'explosifs et de ricine (toxine) lors d'une.
FICHE DE RENSEIGNEMENTS SUR LE RICIN
Il faudrait délibérément fabriquer du ricin et l'utiliser sciemment pour empoisonner quelqu'un. De même l'exposition involontaire au ricin est très peu probable
Comment faire des polyamides à partir de lhuile de ricin ? - Du ricin
ne doit pas faire oublier que l'huile de ricin est à la base aujourd'hui
Antitumor Effects of Ricin AChain Immunotoxins Prepared from Intact
and Fab' Fragments on Solid Human Hodgkin's Disease Tumors in Mice1 to deglycosylated ricin A chain (dg A) to evaluate their potential as.
Fabrication of a SERS based aptasensor for detection of ricin B toxin
02?/11?/2014 Fabrication of a SERS based aptasensor for ... Ag nanoparticles labeled with Bpy and ricin B aptamer which act as SERS probes.
Namibie : expérimentation de la fabrication de biocarburant à partir
Un consortium israélien regroupant Evogène
Conduite à tenir lors dun événement biologique ou chimique
19?/04?/2019 La fabrication et la volonté des terroristes à utiliser des armes ... tutoriels de fabrication d'explosifs et de ricine (toxine) lors d'une.
Attentat au moyen de toxines
ricin 84 mg de ricine et des ustensiles nécessaires à la fabrication d'un explosif sont saisis. Il est reproché à l'islamiste et sa femme d'avoir planifié
CONDUITE A TENIR LORS DUN ÉVÉNEMENT BIOLOGIQUE OU
Les criminels et les terroristes ont démontré leur capacité à fabriquer des mai 2018 :découverte de tutoriels de fabrication d'explosifs et de ricine.
Ricine et risque biologique - ResearchGate
La ricine est une protéine hétérodimérique constituée de deux chaînes A et B de 31 et 34-37 kDa respectivement liées par un pont disulfure [23] (Figure 1) Elle est synthétisée sous la
How to prepare ricin?
Wear a gas mask and gloves. Try to keep the ricin wet at all times to avoid generating any dust (DEADLY!). And always shower and change clothes after handling. 5.Preparation Ricin is a protoplasmic poison prepared from castor beans after the extraction of castor oil therefrom.
How is ricin extracted from Iranian Ricinus communis?
This study undertook extraction and identification of ricin, a toxalbumine, from Iranian Ricinus communis L. Ricin, was extracted from the seeds using dilute acid solution, salted out with ammonium sulfate, and purified by Sephadex G - 75 and DEAE - cellulose column chromatography. Disc electrophoresis showed the degree of the purification.
What is ricin protein?
Introduction Ricin is a highly toxic protein which can be extracted from the castor bean seeds (Ricinus communisL.). This plant is present in all Brazilian regions and explored commercially for its oil, which is mainly used for the production of lubricants, fuel and drugs.
How is ricin precipitated from the water extraction step?
The filtrate from the water extraction step, which contains the ricin, was treated with a 16.7% solution of Na SO to precipitate the protein. This solution is com- "ice posed of 20 pounds of salt in 100 pounds of water and the amount used was such that the salt content equalled 20% of the filtrate weight.
![Antitumor Effects of Ricin AChain Immunotoxins Prepared from Intact Antitumor Effects of Ricin AChain Immunotoxins Prepared from Intact](https://pdfprof.com/Listes/18/3276-18cr0500102929.pdf.pdf.jpg)
ABSTRACT
diseaseinhumans.INTRODUCTION
Received11/13/89;revised2/9/9Ãoe.
Hodgkin'sdiseaseinhumans.
MATERIALSANDMETHODS
antibody. usingthePharmaciaPharmphastsystem. niquesasdescribedelsewhere(17).2929Downloaded from http://aacrjournals.org/cancerres/article-pdf/50/10/2929/2439636/cr0500102929.pdf by guest on 01 October 2023
%blocking= cpminthepresenceofblockingantibody. fortheexperiments. fragments. wascalculatedasfollowsVolume=d2-D--
6 insignificant. analyseshasbeendescribedpreviously(7).RESULTS
Cross-BlockingofHRS-3,Ber-H2,andIRac
100tions.
2930Downloaded from http://aacrjournals.org/cancerres/article-pdf/50/10/2929/2439636/cr0500102929.pdf by guest on 01 October 2023
vivotomaximizetumorcellkill. beenpublishedpreviously(7,12,13).CytotoxicitytoL540CellsinVitro
Immunotoxin1C»(M)
TissueHRS-3Ber-H2IRac
Adrenal
Brain(cortex)
Brainstem
Breast
Cerebellum
Cervix
ColonEsophagus
Gallbladder
HeartKidney
Liver LungLymphnode
Mucosa(nasal)
OvaryParathyroidPros'-'te
Spleen
Stomach(antrum)
Stomach(body)
Testis
ThyroidThyroid(AI)*Thyroid(Hashimoto's)
Tonsils
Uterus
Vagina
Hodgkin'sdisease0
ftAI,autoimmunethyroiditis. cPrimarymaterialandcelllines.Ber-H2dgAHRS-3-dgAHRS-3Fab'dgA
9.0±0.8x10'"
7.0±1.5X10-'"
1.0±0.2x10""
6.0±1.2x10-"'
immunotoxin.AntitumorEffectsonSolidL540TumorsinVivo
2931Downloaded from http://aacrjournals.org/cancerres/article-pdf/50/10/2929/2439636/cr0500102929.pdf by guest on 01 October 2023
Treatmcn!PBSPBSIRac-dgAIRac
dgAIRac dgAIRacIRacFab'dgAIRac
Fab'HRS-3
dgAHRS-3HRS-3Fab'dgAHRS-3
Fab'Ber-H2
dgABer-H2OX?. (Day30/Day1 ratio)9.7±1.6*5.8
±0.70.0
±0.00.8
±0.20.9
±0.47.5
±1.58.0
±2.910.6
±1.91.4
±0.57.5
±1.82.7
±0.77.9±1.54.6
±1.88.8
±1.78.7
±1.1No.of
7257684
51
63
38578
*Mean±SE. cAverageof3separateexperiments.
Averageof2separateexperiments.
0.8I mE o>E _3 O h.OEa)IgGimmunotoxins o 0.810.4•
0.01020
b)IgGantibodies1O2030
Daysaftertreatment
0.4- CO0.0O102030
Daysaftertreatment
tumoreffect(Fig.3A).2932Downloaded from http://aacrjournals.org/cancerres/article-pdf/50/10/2929/2439636/cr0500102929.pdf by guest on 01 October 2023
ofTreatment3;Fig.4).
102030
Daysaftertreatment
group:bars,SE.ImmunotoxinsensitivitvSubline1234L
xIO'"4 x10-'°6 xIO"102 x10-'1 xIO'"M)HRS-3dgA1 x10-6x 10-1 x10-4x10-0t009x
IO'' tumorcellescape. anttotheimmunotoxins.DISCUSSION
2933Downloaded from http://aacrjournals.org/cancerres/article-pdf/50/10/2929/2439636/cr0500102929.pdf by guest on 01 October 2023
cocktails.ACKNOWLEDGMENTS
REFERENCES
Semin.Oncol..13(Suppl.1):23-26.1986.
disease.J.Clin.Oncol..5:556-561,1987. ease.Br.J.Cancer,59:631-635,1989. plantation.Blood,73:340-344.1989.Int.J.Cancer.26:723-731,1980.
1986.celllines.J.Immunol.,139:2081-2087.1987.
20,1980.
1987.Biochem..160:440-443,1987.
2934Downloaded from http://aacrjournals.org/cancerres/article-pdf/50/10/2929/2439636/cr0500102929.pdf by guest on 01 October 2023
CancerRes..47:5042-5046.1987.
4428.1983.
1984.model.CancerRes..48:4862-4867.1988.
Acta.96Â":172-178.1988.
antibody.2935Downloaded from http://aacrjournals.org/cancerres/article-pdf/50/10/2929/2439636/cr0500102929.pdf by guest on 01 October 2023
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