[PDF] benzocaine bac chimie

Is benzocaine soluble in water?

Benzocaine is the ethyl ester of p -aminobenzoic acid (PABA). It can be prepared from PABA and ethanol by Fischer esterification or via the reduction of ethyl p -nitrobenzoate. Benzocaine is sparingly soluble in water; it is more soluble in dilute acids and very soluble in ethanol, chloroform, and ethyl ether.

How is benzocaine prepared?

Benzocaine can be prepared by esterification using 4-aminobenzoic acid and ethanol. It can also be prepared by reduction of ethyl 4-nitrobenzoate to the amine. In industrial practice, the reducing agent is usually iron and water in the presence of a little acid.

Is benzocaine a local anesthetic?

StatPearls [Internet]. Ravneet Singh; Yasir Al Khalili. Last Update: February 25, 2023. Benzocaine is a local anesthetic used in pain control management, and it is in the ester local anesthetic class of medications. This activity describes the indications, action, and contraindications for benzocaine as a valuable agent in managing pain control.

What is benzocaine used for?

It has a role as a topical anaesthetic, an antipruritic drug, an allergen and a sensitiser. It is a benzoate ester and a substituted aniline. Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. It is commonly used for local anesthesia in many over the counter products.