USANA Clinical Research Bulletin - Comparative Bioavailability of
bility of CoQ10 as delivered by four formulas including a new
PRODUCT INFORMATION BOOK
USANA CellSentials Prenatal Vita?Antioxidant 16. USANA CellSentials Prenatal Core Minerals efficiency the cell initiates a natural response called.
USANA 2021 Sustainability Report
major steps to make USANA a more sustainable company for its future and the to empower USANA employees to give ... the microbiome natural product.
CERTIFIED FOR SPORT
The featured athletes are either Associates or dedicated product users who have received complimentary USANA products and/or compensation for their
Do USANA Products Contain Animal Derivatives
USANA makes every effort to avoid using ingredients derived from animal source or animal by-products. However it has not been possible to entirely
Nutritional sciences company drives global business efficiency with
That's where USANA Health. Sciences comes in. USANA—a word with Latin roots meaning “true health”—formulates manufactures
17CV0320 BGS LAB
NATURE OF THE ACTION. The NutriSearch Comparative Guide to Nutritional world's largest direct sales supplement companies Usana Health. Sciences
USANA 2021 Sustainability Report
major steps to make USANA a more sustainable company for its future and the to empower USANA employees to give ... the microbiome natural product.
ENJOY LIFE MORE WITH USANA MOOD AND RELAXATION
When taken at bedtime Pure Rest supports the body's natural circadian rhythms. They signal your body that it's time to sleep. Get truly reliable levels of
USANA 2020 Sustainability Report: Healthiest Family
following pages USANA's first Sustainability Report which reviews how we are managing the microbiome
1 Recommended Citation: Cuomo J, Rabovsky A. Comparative Bioavailability of Coenzyme Q 10 in Four Formu- lations. 2000. USANA Clinical Research Bulletin, USANA Health Sciences, Inc. SLC, UT. CLINICAL RESEARCH BULLETIN
Comparative Bioavailability of Coenzyme Q
10 in Four Formulations * USANA Health Sciences, Inc. Salt Lake City, Utah, USA. oenzyme Q10 (CoQ10) plays an essential role in mitochondrial electron transport, and as such it is fun- damental for energy production in cells. 1Further, CoQ10 is an an-
tioxidant whose activity is par- ticularly important in regenerat- ing vitamin E. Its ability to quench free-radicals also helps maintain the structural integrity and stability of mitochondrial and cellular membranes - including intracellular membranes.2Studies
have shown therapeutic benefits for CoQ10 supplementation, the best documented of which involve cases of heart failure and ischem- ic heart disease.3Because CoQ10 is a lipid-
soluble nutrient, its bioavailabili- ty from pharmaceutical and nu- tritional products can be limited.USANA uses a patented solubili-
zation system in its current Co-Quinone product, which is highly
effective in promoting high CoQ10 absorption. However, many of the solubilizing ingre- dients are synthetic, and ideally an all-natural formula would be preferable. This study was de- signed to compare the bioavaila- bility of CoQ10 as delivered by four formulas, including a new, proprietary, all-natural formula developed by USANA scientists.Methods
This prospective crossover
study involved 14 healthy subjects.Four coenzyme Q10 formulations
were prepared: a dry tablet with- out cyclodextrins, a dry tablet containing a preformed cyclodex- trin-CoQ10 complex, the currentUSANA CoQuinone liquid formu-
la in a soft-gel capsule, and USA-NA's new proprietary liquid for-
mula in a hard gelatin capsule.Given the crossover design, each
subject participated in each of the four treatments in serial fa- shion, with a washout period (six days) between treatments. On the morning of the first test, subjects reported to the la- boratory for a baseline blood draw. After the blood draw, each participant was given a CoQ10 supplement with a standard meal.Additional blood samples were
then drawn at 3, 5, and 8 hours after supplementation. This pro- tocol, beginning with a baseline blood draw, was repeated three more times as the subjects ro- tated through the four treatments.All blood samples were
processed, and plasma fractions were analyzed for CoQ10 viaHPLC with an electrochemical
detector. Increases from baseline in plasma CoQ10 concentrations were calculated, and statistical comparisons between treatments were run. In addition, increases in plasma CoQ10 were plotted as a function of time following sup- plementation, and area under the curve (AUC) was calculated as an indicator of bioavailability over C 2 Recommended Citation: Cuomo J, Rabovsky A. Comparative Bioavailability of Coenzyme Q 10 in Four Formu- lations. 2000. USANA Clinical Research Bulletin, USANA Health Sciences, Inc. SLC, UT. time. Statistical comparisons were also made for these AUCs.Results
The four formulas showed
dramatic differences in CoQ10 bioavailability (Figures 1 and 2).The dry tablet formula without
quotesdbs_dbs2.pdfusesText_4[PDF] euseius gallicus en premiere ligne de defense - France
[PDF] euskadi,pays basque sauvage
[PDF] Euskal deiturak
[PDF] Euskal Herriko leku-izenak
[PDF] Euskal Trail
[PDF] Euskoaren zerbitzu-emaile berriak Liste des nouveaux - Anciens Et Réunions
[PDF] EUSSC IX – 2010 Il Latino e le culture dell`Europa, 23 settembre - France
[PDF] Eutech EcoTestr pH 1 pocket tester - France
[PDF] euthanasie
[PDF] Euthanasie aux Pays Bas : mise en garde des Nations
[PDF] Euthanasie débat dépassé
[PDF] euthanasie des chiens - Canine Rabies Blueprint - Médecine Vétérinaire
[PDF] euthanasie du point de vue du philosophe Bertrand Vergely
[PDF] Euthanasie et dignité humaine - Paroisse Saint-Symphorien
