[PDF] acetylation of alcohol mechanism

  • What is the mechanism of acetylation of alcohol?

    The process of acetylation occurs when the alcohols are introduced to acetic acid, at high temperature, with toluene as a solvent, generating an acetylated compound that takes heavily from the strength of borated zirconia.

  • What is the mechanism of action of acetylation?

    The mechanism of acetylation begins with the protonation of the acetyl group by a strong acid. This results in two oppositely charged ions; the acetyl-bound compound is positively-charged and the deprotonated acid (now a conjugate base) is negatively-charged.

  • Does alcohol undergo acetylation?

    The acetylation of benzyl alcohol with acetic anhydride gave 63% conversion with 100% selectivity of benzyl acetate after 24 h at room temperature (Table 1, entry 1). Interestingly, complete conversion of benzyl alcohol with 100% selectivity to benzyl acetate was achieved at 60 °C after 7 h (Table 1, entry 1).
  • In chemistry, acetylation is an organic esterification reaction with acetic acid. It introduces an acetyl group into a chemical compound. Such compounds are termed acetate esters or simply acetates. Deacetylation is the opposite reaction, the removal of an acetyl group from a chemical compound.
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