D.H. Ripin D.A. Evans pKas of Inorganic and Oxo-Acids Chem 206 PDF

Protonated carbonyl pKa = -7 Other important pKa's. 2. Protonated alcohol or ether pKa = -2 to -3. H2 = 35. 3. Carboxylic acid pKa = 4-5 Amide pKa = 18.

accurate prediction of the aqueous pKa values of sulfonamide drugs

29 May 2019 For primary benzene sulfon- amides (Pr-BSA Set 1 or S1)

D.H. Ripin D.A. Evans pKas of Inorganic and Oxo-Acids Chem 206

*Values <0 for H2O and DMSO and values >14 for water and >35 for DMSO were extrapolated using various methods. 38. (12) (estimate). pKa's of Nitrogen Acids.

pKa Shift Effects on Backbone Amide Base-Catalyzed Hydrogen

that the amide pKa directly influences the HX rate. Using the finite-difference solution of the Poisson-. Boltzmann equation we investigated the

Theoretical Study on Acidities of (S)-Proline Amide Derivatives in

23 Dec 2009 The pKa values of a series of chiral amides were also studied in this work. Finally we applied the theoretical method to predict a large number ...

pka bases.cdx

pKa 35.7 lithium diisopropyl amide. LDA. pKa 35 amide. H3C OH. pKa 15-16 Note; The pKa values associated with bases is normally meant to refer to the ...