[PDF] List of Drugs to be Avoided by Patients with Congenital Long QT





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Terry White Chemists Cephalexin

alcohol and in ether. The cephalosporins differ from penicillins in the structure of the bicyclic ring system. Cephalexin has a d-phenylglycyl group as 



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It is practically insoluble in alcohol and in ether. The cephalosporins differ from penicillins in the structure of the bicyclic ring system. Cephalexin.



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CEPHALEXIN. 250MG CAPSULE. 00342084. TEVA-CEPHALEXIN CEPHALEXIN-500 ... For patients who have been abstinent from alcohol for at least.



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Cephalexin (cefalexin) is an antibiotic It is safe to use with alcohol but it can worsen symptoms of nausea and indigestion For this reason it may be better 



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It is practically insoluble in alcohol and in ether The cephalosporins differ from penicillins in the structure of the bicyclic ring system Cephalexin has a d 



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Keflex (cephalexin monohydrate) antibiotic medicine information

Keflex (cephalexin monohydrate) is an antibiotic used to treat infections Keflex Print Friendly PDF Email Generic Name: cephalexin monohydrate

  • Is it OK to drink alcohol with Keflex?

    Cephalexin (cefalexin) is an antibiotic. It is safe to use with alcohol, but it can worsen symptoms of nausea and indigestion. For this reason, it may be better to avoid alcohol during treatment.
  • Can you drink alcohol with cephalosporins?

    In conclusion, it is important for clinicians to educate patients that no alcohol should be used if one is taking cephalosporin. Also, clinicians should keep in mind that cephalosporin should not be prescribed for any alcoholics.
  • What to avoid with Keflex?

    Cephalexin and multivitamin with minerals should not be taken orally at the same time. Products that contain zinc may interfere with the absorption of cephalexin into the bloodstream and reduce its effectiveness. You should take multivitamin with minerals at least three hours after taking cephalexin.
  • Many people taking antibiotics already experience stomach or digestive side effects, and drinking alcohol while on these medications can increase feelings of nausea. In addition to gastrointestinal issues, both alcohol and antibiotics can hinder cognitive function, concentration, and coordination.

BC INHERITED St. Paul's Hospital (Vancouver) Royal Jubilee Hospital (Victoria) Northern Outreach Clinic (Hazelton)

ARRHYTHMIA Ph: 604-682-2344 Ext. 66766 Ph: 250-727-4461 Ph: 250-727-4461

PROGRAM

List of Drugs to be Avoided by Patients with Congenital Long QT Syndrome (LQTS)* updated Feb 2017

*This list is not comprehensive but is meant to be a practical list for those clinicians managing patients with LQTS in Canada. Patients with LQTS should discuss ALL new medications

(prescription and over the counter) with a health care provider. The most up to date information is available on

www.crediblemeds.org. There is also a mobile app free for iPhone/Android.

Drugs with ABSOLUTE

CONTRAINDICATION Drugs with RELATIVE/THEORETICAL CONTRAINDICATION

PRESCRIPTION DRUGS PRESCRIPTION DRUGS

Amiodarone

Amitriptyline (Elavil)

Atomoxetine (Stattera)

Azithromycin (Zithromax)

Chloroquine (Aralen)

Chlorpromazine

Ciprofloxacin

Citalopram (Celexa)

Clarithromycin

Disopyramide (Rythmodan)

Dolasetron (Anzemet)

Domperidone

Doxepin

Dronedarone (Multaq)

Droperidol

Erythromycin

Escitalopram (Cipralex)

Flecainide (Tambocor)

Fluconazole

Gatifloxacin (Tequin)

Haloperidol (Haldol)

Ibutilide (Corvert)

Levomepromazine (Nosinan)

Maprotiline

Methadone (Metadol)

Mexiletine

Moxifloxacin (Avelox)

Ondansetron (Zofran)

Oxaliplatin (Eloxatin)

Papaverine HCl

Pentamidine

Pimozide

Procainamide

Propafenone (Rythmol)

Propoxyphene

Propofol (Diprivan, Provoven)

Quinidine

Saquinavir (Invirase)

Sotalol

Trazodone

Vandetanib (Caprelsa)

Alfuzosin (Xatrol)

Amantadine

Aripiprazole (Abilify)

Atazanavir (Reyataz)

Bretylium

Buprenorphine (BuTrans 5, 10, 20 and in

Suboxone)

Capecitabine

Chloral hydrate

Clomipramine

Clozapine

Cyclobenzaprine, theoretical

Cyclosporin (Neoral)

Dasatinib (Sprycel)

Degarelix (Firmagon)

Desipramine

Desvenlafaxine (Pristiq)

Dextroamphetamine

(Dexedrine and in Adderall)

Dobutamine

Donepezil (Aricept)

Dopamine

Ephedrine

Fingolimod (Gilenya)

Fluoxetine (Prozac)

Formoterol (Oxeze Turbuhaler and in

Symbicort)

Furosemide (Lasix)

Galantamine (Reminyl)

Granisetron (Kytril)

Hydroxychloroquine (Plaquenil)

Hydroxyzine

Imipramine

Indapamide (Lozide and in Coversyl Plus)

Isoproterenol

Itraconazole (Sporanox)

Ketoconazole (Nizoral)

Lapatinib (Tykerb)

Leuprolide (Lupron)

Levofloxacin (Levaquin)

Lisdexamfetamine (Vyvanse)

Lithium (Carbolith)

Loperamide (Imodium)

Mefloquine (Larium)

Methylphenidate (Ritalin, Concerta)

Metoclopramide

Midodrine

Mirtazapine (Remeron)

Nilotinib (Tasigna)

Norepinephrine

Nortriptyline

Norfloxacin

Octreotide (Sandostatin)

Olanzapine (Zyprexa)

Ofloxacin

Orciprenaline

Orphenadrine (Norflex)

Oxycodone (OxyNEO and in Oxycocet)

Oxytocin

Paliperidone (Invega)

Paroxetine (Paxil)

Pazopanib (Votrient)

Perflutren lipid microspheres (Definity)

Perphenazine

Posaconazole (Posanol)

Promethazine

Quinine

Quetiapine (Seroquel)

Risperidone (Risperdal)

Ritonavir (Norvir)

Ritonavir / Lopinavir (Kaletra)

Salbutamol (Ventolin)

Salmeterol (Serevent and in Advair)

Sertraline (Zoloft)

Solifenacin (Vesicare)

Sorafenib (Nexavar)

Spiramycin (Rovamycine)

Sunitinib (Sutent)

Tacrolimus (Prograf, Protopic)

Tamoxifen

Terbutaline (Bricanyl Turbuhaler)

Thiothixene (Navane)

Tizanidine (Zanaflex)

Tolterodine (Detrol)

Torsemide (Demdex)

Trimethoprim / Sulfamethoxazole (Septra)

Trimipramine

Vardenafil (Levitra)

Venlafaxine (Effexor)

Voriconazole (VFend)

Vorinostat (Zolinza)

Ziprasidone (Geodon,Zeldox)

Drugs with RELATIVE/THEORETICAL CONTRAINDICATION (continued)

OVER THE COUNTER DRUGS

Cetirizine (Reactine), minor

Diphenhydramine (Benadryl), minor

Epinephrine (EpiPen, Twinject)

Famotidine (Pepcid)

Ginseng (Cold - FX)

Loratidine (Claritin), theoretical

(no reports)

Phenylephrine (Sudafed PE and in combination

Decongestants)

Pseudoephedrine (Sudafed and in combination

Decongestants)

STREET DRUGS

Amphetamine (bennies, speed, uppers)

Cocaine (blow, C, coke, crack, rock, snow)

Methamphetamine (chalk, crystal meth, ice,

meth), Methylenedioxy-methamphetamine or MDMA (E, ecstasy, MDA, X)

Oxycodone (killers, OCs, oxycotton, oxys)

Quetiapine (baby heroin, Suzie-Q) [mixed with other drugs]

BC INHERITED St. Paul's Hospital (Vancouver) Royal Jubilee Hospital (Victoria) Northern Outreach Clinic (Hazelton)

ARRHYTHMIA Ph: 604-682-2344 Ext. 66766 Ph: 250-727-4461 Ph: 250-727-4461

PROGRAM

QT Prolonging Drugs-Alternatives

Below is a list of alternatives to some QT prolonging drugs. All patients with Long QT syndrome should

speak to a health care provider or pharmacist prior to taking any new over-the-counter or prescription drug.

Any questions or concerns can be directed to the BC Inherited Arrhythmia Program during regular

business hours, or to the Electrophysiologist on call at St. Paul's Hospital or Royal Jubilee Hospital after

hours or on weekends. The most up to date information on QT prolonging drugs can be found at www.crediblemeds.org. A free mobile app is also available for iPhone/Android.

Anti-depressants Citalopram Mirtazapine

Antibiotics

Azithromycin, Floxacins,

Clarithromycin

Penicilin based antibiotics (Penicillin, Amoxicillin, Ampicillin), Doxycycline, Tetracycline, Sulfa based antibiotics (Septra, Bactrim), Cephalosporins (Cephalexin, Cefuroxime, Ceftriaxone) Anti-psychotics Haldol, Quetiapine (Seroquel) Refer to a specialist Anesthetics Propofol Midazolam and/or Refer to a specialist Analgesic/narcotic Methadone Refer to a specialist

Anti-arrhythmic Sotalol Refer to a specialist

Anti-histamines++ Diphenhydramine (Benadryl) Loratadine, cetirizine

*** Always consult with a heart rhythm specialist or pharmacist if there are any questions or doubts about

QT prolonging drugs or these suggested alternatives

++ If a patient must take an antihistamine, certirizine (and perhaps loratadine) are likely the "safest" based on the

current literature. If taking certirizine, no other current medications should be taken (eg. avoid any P450 inhibiting

drugs). Renal and liver function should be normal Monitoring Recommendations for Patients on QT Prolonging Drugs • 12 lead resting ECG before starting the drug to obtain a baseline • Repeat 12 lead resting ECG 7-14 days after drug start date and/or change in does • If there is a 50 ms increase in QTc OR the QTc > 500 ms, o REDUCE dose and repeat ECG o AVOID drug and seek an alternative if at all possible • ECGs can be sent to the BCIAP for review by heart rhythm specialist • Goal is for patient to take the least amount/dose needed to achieve the target statequotesdbs_dbs21.pdfusesText_27
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