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Biochemistry and Metabolism The content review presented here

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12 Bioenergetics and Regulation of Metabolism. 48. General Chemistry General Chemistry 2: The Periodic Table ... 1H-NMR Shifts to Know for the MCAT.



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metabolism. In an FAO disorder fatty acids and potentially toxic derivatives accumulate because of a deficiency in one of the mitochondrial FAO enzymes.



Using MCAT® Data in 2023 Medical Student Selection

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Pathway com With PhD degrees in Biochemistry and decades of MCAT Energy Metabolism including free energy ATP and acetyl CoA



[PDF] MCAT REVIEW SHEETS Med-Pathway

11 Lipid and Amino Acid Metabolism 47 12 Separations and Purifications 24 12 Bioenergetics and Regulation of Metabolism 48 General Chemistry Biology



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[PDF] A Road Map to MCAT Content In Biochemistry Textbooks

Introduction The publishers of the textbooks listed in this publication have provided a “road map” to where the MCAT Foundational Concepts and Content

  • Which metabolic pathways to memorize for MCAT?

    The primary biochemical pathways that you need to be familiar with for the MCAT are glycolysis, fermentation, Krebs Cycle, electron transport chain/oxidative phosphorylation, gluconeogenesis, glycogenolysis, glycogenesis, fatty acid synthesis, beta-oxidation of fatty acids, and pentose phosphate pathway.
  • Do you have to memorize the metabolic pathways for MCAT?

    Although the MCAT doesn't expect you to know every single thing about every single biochemical pathway, they do expect you to have the key details of the most important pathways memorized to a T.
  • How to memorize glycolysis for MCAT?

    Ken Tao is the MedSchoolCoach expert on MCAT, and will help you remember glycolysis intermediates with the word trick: Girls get fine food; Gentlemen dine girls; Boys prefer to pick up pepperoni pizza.
  • Metabolism consists of a series of reactions that occur within cells of living organisms to sustain life. The process of metabolism involves many interconnected cellular pathways to ultimately provide cells with the energy required to carry out their function.

MCAT REVIEW SHEETS

Revised 2019

Please send questions or comments to:

MileDown.MD@Gmail.com

i

Contents

1 Atomic Structure 1 1 The Cell 25

2 The Periodic Table 2 2 Reproduction 26

3 Bonding and Chemical Interactions 3 3 Embryogenesis and Development 27

4 Compounds and Stoichiometry 4 4 Nervous System 28

5 Chemical Kinetics 5 5 Endocrine System 29

6 Equilibrium 6 6 Respiratory System 30

7 Thermochemistry 7 7 Cardiovascular System 31

8 The Gas Phase 8 8 Immune system 32

9 Solutions 9 9 Digestive System 33

10 Acids and Bases 10 10 Kidney and Skin 34

11 Oxidation-Reduction Reactions 11 11 Muscular System 35

12 Electrochemistry 12 12 Genetics and Evolution 36

1 Nomenclature 13 1 Amino Acids, Peptides, and Proteins 37

2 Isomers 14 2 Enzymes 38

3 Bonding 15 3 Nonenzymatic Protein Function & Protein Analysis 39

4 Analyzing Organic Reactions 16 4 Carbohydrate Structure and Function 40

5 Alcohols 17 5 Lipid Structure and Function 41

6 Aldehydes and Ketones I 18 6 DNA and Biotechnology 42

7 Aldehydes and Ketones II 19 7 RNA and the Genetic Code 43

8 Carboxylic Acids 20 8 Biological Membranes 44

9 Carboxylic Acid Derivatives 21 9 Carbohydrate Metabolism I 45

10 N- and P-Containing Compounds 22 10 Carbohydrate Metabolism II 46

11 Spectroscopy 23 11 Lipid and Amino Acid Metabolism 47

12 Separations and Purifications 24 12 Bioenergetics and Regulation of Metabolism 48

General Chemistry Biology

Organic Chemistry Biochemistry

ii MM CM: RaRDGMurqM:HluC RWMEIMAMNWDur VMelHE .TWGMeREERrMFuEH.MDmM sMIHr.uT RrMurqMdHWVHoT RrMnKM:MPlHMXHuWTMurqMNOGDHrMPWur.oRWTMDEM mMVHuWr rDMurqMQHERWGMnCMeM:Wu rMDnM EMeRDr T RrRMeRr.V RS.rH..RMurqMVurDSuDHMnsMBM@rqRVW rHMNWDur.MurqMXRWERrH.MDcM nMQRT CuT RrRM@ERT RrRMurqMITWH..MnmM@MVutMPHVlr JSH.MDDM cMwqHrT TGMurqMdHW.Rrua TGMnEMTMBFAMurqMiFAMDGM DMd.GVlRaRD VuaMB .RWqHW.MnnMLMBFAMiHoa VuT RrMDIM GMIRV uaMdWRVH..H.RMATT TSqH.RMurqM:HluC RWMncMXMPlHMeHrTWuaMBRDEuMGKM

IMIRV uaMwrTHWuVT RrMnDMwMAE rRMAV q.MGCM

CKMIRV uaMPl rM rDMnGMYM@rSGEHMwrl t T RrMGsM

CCMIRV uaMITWSVTSWHMurqMBHERDWuol V.MnIMHMQHTutRa .EMNCHWC HZMGmM

CsMIRV uaMITWuT W VuT RrMcKMVMLaGVRaG. .MGEM

QMLaSVRrHRDHrH. .MGnM

M

FMe TW VMAV qMeGVaHMGcM

NMNO quT CHMdlR.olRWGauT Rr GDM

CMH rHEuT V.MurqMBGruE V. cC dMQRWHMQHTutRa VMduTlZuG.MGGM sM[RWMMurqM@rHWDG cs \M@..HrT uaM@JSuT Rr.MGIM mMPlHWERqGruE V. cm

EMTaS q. cE

nM@aHVTWR.TuT V.MurqMQuDrHT .E cn cMe WVS T. cc

DM[uCH.MurqMIRSrq cD

GMV DlTMurqMNoT V. cG

IMATRE VMurqMFSVaHuWMdlHrREHru cI

CKMQuTlHEuT V. DK

CCMBH. DrMurqM@OHVST RrMRWMiH.HuWVl DC

CsMBuTuP:u.HqMurqMITuT .T VuaMiHu.Rr rD Ds

Behavioral SciencesAppendix

Physics and Math

General Chemistry 1: Atomic Structure

1 Rutherford Model: eteeiEEoRMdPAnCHEHuAAnuCrETECudRMuHiE Bohr Model: eteciEmMHdAS:MrEnA:SPHESCEWnAMErMPTSRiE

DTAPIMAEnA:SPHEwEEnergy

Photon emitted when n¯, absorbed when n

Heisenberg Uncertainty: CPESHESWDnHHS:RMEPnEECnGEPIMEWnWMCPuWETCrE

DnHSPSnCEHSWuRPTCMnuHRliE

Hund's Rule: M

F

ITHMEeEM

F iE EE

Pauli Exclusion Principle:

@TSAMrEM F

EWuHPE:ME+

BE- iE E E qdSMCPSHPEVnCPAS:uPSnCHE sIomEJCMWnCSdE

Absorb light

Higher potential

Excited

Distant from nucleus

sE LE sEwEJTHHECuW:MAEwEDAnPnCHEMECMuPAnCHE

NENEwEsPnWSdECuW:MAEwEOEnGEDAnPnCHE

E

PnPMaEEsPnWSdEQMS.IPEwEGMS.IPMrETHMAT.ME

E

VnCHPTCPHERS.IPEoCMA.lE

l =h =frequency h=Planck 8 sconstantEE c=speedoflight E E

Diamagnetic:

sRREMRMdPAnCHETAMEDTSAMrE

So@oRRomE:lETCEMKPMACTREWT.CMPSdEGSMRrE

Paramagnetic:

eEnAEWnAMEuCDTSAMrEMRMdPAnCHE @TRRomESCPnETCEMKPMACTREWT.CMPSdEGSMRrE nA:SPTRHEITHMEVuHPETEHSC.RMEMRMdPAnCBEPIMETPnWESHEparamagnetic. If there are no unpaired electrons, then the atom is diamagnetic.

Examples:

IMEwEeH

W

EwEdiamagnetic and will repel magnetic fields.

C = 1s

2 2s 2 2p 2 = paramagnetic and will be attracted to magnetic fields. E E mSTWT.CMPSdEHHiE@TATWT.CMPSdE

XuTCPuWE

PuW:MAE

PTWMEQITPESPERT:MRHE

@nHHS:RME

YTRuMHE

PnPMHE

n @ASCdSDTR EM F

EMCMA.lERMHMREnAE

PIMEHIMRREOEWTPdIMHEPIMEAnGEnGE

PIMEDMASnrSdEPT:RM

iE l s[SWuPITREcmEHITDMEnGEnA:SPTRE\BEeBEWBEZBECFeE\EwEs orbital 1 = p orbital 2 = d orbital 3 = f orbital 4 = g orbital ml

JT.CMPSdE^A:SPTREHu:FPlDMECCPM.MAHE

_l ® +l E ms qDSC

EoRMdPAnCEHDSCE

BE- E E

Maximum e

in terms of nEwEWn WE

Maximum e

in subshell = 4l + 2 Free Radical: An atom or molecule with an unpaired electron. E E

XuTCPuWEPuW:MAHE

Avogadro's Number: 6.022×10

#F =1molE

Planck's (h): 6.626×10

HFIE `•s

Speed of Light (c)

3.0×10

K m s E E E E

3D shapes of s, p, d, and f orbitals

Atomic Orbitals on the Periodic Table

The Aufbau Principle

General Chemistry 2: The Periodic Table

2

Alkali Metals

Alkaline Earth Metals

Transition Metals

Post Transition Metals

Metalloids

Non-metals

Halogens

Noble Gases

i MooE rCuITCcMqE nmRREtMP:MMCECmuRMmHEDEwTRMCuMEM .E @G E

BdHMEM

E C HP

E@dCSDTPSdCEMCMAcSMHE

GE E

E TSCEM

E DH rxn < 0 when gaining e but EA is reported as positive value KEE

LdtRME THMHEITwME

CdETooSCSPlEodAEM

MEE@PE

:dmRqEPTNMEMCMAclE

PdEodAuMETCEM

EdCE PIMWE GL E

OdAuMEPIMETPdWEMGMAPHE

dCETCEM

ESCETEtdCqE

PoEPIMELdtRME THMHQEdCRlE

RAETCqESM

EITwMETCEGLE

VdWWdCEGRMuPAdCMcTPSwSPSMHE

EH C N O F

GGTuPE

eMeIEeMTTEUMIVEUMVVEUMWKE

» eMIEeMTEUMIEUMTEVMIE

E E

EPdWSuE

XSDM E

PCRlEPAMCqEPISHEqSAMuPSdCE

VTPSdCHEHELMmPATREHEECSdCHE

0 RAE SME

Rare Earth Metal Rows

General Chemistry 3: Bonding and Chemical Interactions 3

Hybridization

e

Groups

dAWaSRH qPSIAVuHdIWtH

Bonded

Pairs Lone Pairs

Electronic

ePWtPIAM H

Molecular

DwVsPH

Bond Angle HiE oE oE rEcE rE mSCMTA E mSCMTA E mSCMTA E r:c° Hi oE eE eE oE rE cE rE oEDASqnCTREwRTCTAE

DASqEwRTCTAE

sMCP E mSCMTA

Eroc°

Hi eE .E .E eE oE rE cE rE oE eE

DMPATIMdATRE

DMPATIMdATRE

DASqEwlATWSdTRE

sMCP E mSCMTA E rc@GB° Hi e dE BE BE .E eE oE cE rE oE e E

DASqnCTRE

sSilATWSdTRE

DASqnCTREsSilATWSdTRE

CMMHTDE

DECITiMdE

mSCMTA E @c°

120°

Hi e d o E GE GE BE .E cE rE oEHuPTIMdATRE

HuPTIMdATRE

CIJTAMEwlATWSdTR

E

CIJTAMEwRTCTAE

@c° tCPMAWnRMuJRTAEKnAuMHEKnAWTREVITAqME

FormalCharge=valencee

0 -dots-sticksE

Dots: LnCMnCdSCqEM

EE

Sticks: wTSAEnNEMnCdSCqEMRMuPAnCHE

E E

VnOTRMCPEsnCdHE

Hydrogen O-H, N-H, F-H

Dipole-Dipole

London Dispersion

E

Strength

CSqWTETCdEwSEsnCdHE

rEs rEs 1 p rEs 2 p E E Covalent Bond: KnAWMdEOSTEPIMEHITASCqEnNEMRMuPAnCHEMMPDMMCE

PDnEMRMWMCPHEnNEHSWSRTAEQLGE

Bond Order: RMNMAHEPnEDIMPIMAETEunOTRMCPEMnCdESHETEHSCqRMVE bond strength, bond energy, bond length¯.

Nonpolar Bonds: DEN < 0.5.

Polar Bonds: DEN is between 0.5 and 1.7.

Coordinate

Covalent Bonds:

E tnCSuEsnCdHE Ionic Bond: KnAWMdEOSTEPIMEPATCHNMAEnNEnCMEnAEWnAMEMRMuPAnCHE

DEN > 1.7.

Cation: wHCtDtPQE\E

Anion: LQ WDtPQE-E

Crystalline Lattices: Large, organized arrays of ions. E

Electronic Geometry:

snCdMdETCdERnCMEiTSAHEPAMTPMdEPIMEHTWMGE Molecular Shape: mnCMEiTSAHEPT^MEJiERMHHEHiTuMEPITCETEMnCdEPnETCnPIMAETPnWGE E E Note: Van de Waals Forces is a general term PITPESCuRJdMHE

UEsnCdETuuMiPnAE

E E

UEsnCdEdnCnAE

Bond Type According to DEN

0

LnCinRTAE

unOTRMCP 0.5 wnRTAE unOTRMCP 1.7 tnCSuE E E

General Chemistry 4: Compounds and Stoichiometry

4

Combination

: iosEsAEWsAMEAMTtPTCPHErsAWSCcEsCMEnAsqdtPE m:mEDcwE.E@mEDcwE® 2Hm@EDcwE

Decomposition: uSCcRMEAMTtPTCPEGAMTBHEqsoCE

m:c@EDHwE® 2HgEDRwE.E@mEDcwE

Combustion

: CCDsRDMHETErdMREEdHdTRRlETEIlqAstTAGsCEETCqE@mEDcwE

VsWWsCRlErsAWHEV@mETCqE:m@E

V:eEDcwE.Em@mEDcwE® COmEDcwE.E:m@EDcwE

Single-Displacement: FCETPsWGSsCESCETEtsWnsdCqESHEAMnRTtMqEGlE

TCsPIMAETPsWGSsCE

VdEDHwE.EFcH@IEDTJwE® AgEDHwE.EVdH@IEDTJwE

Double-Displacement:

(metathesis)

KRMWMCPHErAsWEPosEtsWnsdCqHEHoTnEnRTtMHE

VTVRmEDTJwE.EmFcH@IEDTJwE® Ca(NOIwmEDTJwE.EmFcVREDHwE Neutralization: FEPlnMEsrEqsdGRMLAMnRTtMWMCPEAMTtPSsCE

FtSqE.EGTHME® salt + H2O

:VREDTJwE.EHT@:EDTJwE® NaClEDTJwE.E:m@EDRwE E

KJdSDTRMCPHEMEHsAWTRSPl

E

Equivalent

Mass:

NTHHEsrETCETtSqEPITPElSMRqHEOEWsRMEsrE:

EsAE PE E GEW =

Equivalents =

!$''",-"!."/01 234
EE E

Normality =

35
6 EE E

QsAETtSqHEEPIMEREsrEMJdSDTRMCPHE

DCwESHEPIMEREsrE:

ETDTSRTGRME

rAsWETErsAWdRTEdCSPP E

Molarity =

0"%!$#789

EE E E

VsWnsdCqEQsAWdRTHE

ilnMHEsrESMTtPSsCHE

HTWSCcECsCHE

QsAEMRMWMCPHEDdHdTRRlEWMPTRHwEPITPEtTCE

rsAWEWsAMEPITCEsCMEnsHSPSDMESsCEEPIME nTAMCPIMHMHErsRRsoSCcEPIMECTWMEsrEPIME

MRMWMCPE

QM m.

ECAsCDCCwE

QM I.

ECAsCDCCCwE

Vd

EVsnnMADCwE

Vd m.

EVsnnMADCCwE

E @RqMAEWMPIsqaETsdHETCqETStEPsEPIMETPsWHE oSPIERMHHMAETCqEcAMTPMAEtITAcMEE

AMHnMtPSDMRlEQM

m.

EQMAAsdHE

QM I.

EQMAAStE

Vd

EVdnAsdHE

Vd m.

EVdnAStE

E

NsCTPsWStETCSsCHEqAsnEPIMEMCqSCcEsrEPIME

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