[PDF] [PDF] Welcome to Part 1 in our series of Carbohydrate lectures In this

[PDF] Questions- Carbohydrates A The following structure is D-sorbose

a) They are diastereomers that are also epimers b) They c) D-gulose has more diastereomers than D-ribose ______ The open-chain structure of L-talose

[PDF] Chirality - Organic Chemistry

Drawing the Three-Dimensional Structure of a Chiral Molecule Draw the structure of a (d) Draw the structure of a diastereomer of ribose 9 58 On catalytic 

[PDF] Welcome to Part 1 in our series of Carbohydrate lectures In this

deoxyribose and ribose required for nucleic acid biosynthesis Fischer projections are a useful way to represent the 3-dimensional structure of sugars in only two So how do you convert the Fischer projection back into a line angle drawing, that you are Stereoisomers can be classified further as either diastereomers or 

[PDF] R and S Nomemclature

Lecture 16 Problem 1 - Draw a 3D structure and its mirror image for each of the following molecules Are they Are they meso, enantiomers or diastereomers?

[PDF] Isomer Overview The following table summarizes the various types

Diastereomers – stereoisomers that are not mirror images of each other, can be a result of either (R/S) draw a 2D structure we can identify any chiral centers L -ribose L-arabinose D-xylose D-lyxose L-xylose L-lyxose H OH CH2OH C

[PDF] Structural Isomers And Stereoisomers

10 2 Drawing Structures for Chiral Molecules: Fischer Projection Formula We draw the carbon chain vertically and place the groups in the first stereoisomer rather arbitrarily We chose (for no fructose, ribose, and deoxyribose The Fischer 

[PDF] Chapter 11: Carbohydrates

Given the Haworth structures of two monosaccharides, be able to draw the For example, the stereoisomer of glucose that is made in photosynthesis is Draw the Fischer projection of the alcohol sugar that is formed when D-ribose (shown 

[PDF] Problems for Chapter 2 - MSU chemistry

of the sugar ribose Ph Draw structures for the compounds named systematically here Explain the formation of essentially one stereoisomer in this reaction

[PDF] Sheet 11-A - Doctor 2019

Structure of insect) are used to form larger molecules They : Building blocks antigens and and scell-self (DNA, RNA), like ribose and deoxyribose Diastereomers that differ in the orientation of one chiral carbon epimers Enantiomer Haworth representation: is a way to draw and represent sugars in a cyclic or a ring

[PDF] AK - Chemistry 205 Chemistry 2050 “Introduction to Organic

Ribose and Deoxyribose and Their Phosphate Esters 20 Question 5 structure is D-______ (erythrose, threose) Draw the corresponding Fischer projection

[PDF] draw the structure of a dicotyledonous animal pollinated flower

[PDF] draw the structure of a dipeptide

[PDF] draw the structure of a nucleotide and label the parts

[PDF] drawing group euro 2020

[PDF] drawing kualifikasi euro 2020

[PDF] dresden porcelain marks crown

[PDF] dresden porcelain marks germany

[PDF] dreux france air force base

[PDF] drinking age in california 1960

[PDF] drinking age in california 1972

[PDF] drinking age in california 2018

[PDF] drinking age in california 2019

[PDF] drinking age in california history

[PDF] drinking age in california in 1975

[PDF] drinking age in california with parents

WelcometoPart 1inourseriesofCarbohydratelectures.Inthissection,youwilllearn 1 deoxyribose 2 Carbohydrates,astheir nameimplies,arewaterhydratesofcarbon,andtheyallhavethe samebasiccoreformula(CH 2 O) n andarealwaysfoundintheratioof1carbonto2 3 Carbohydratescanbedividedintosubcategoriesbasedontheircomplexity. Thesimplest bond.Oligosaccharidesarepolymers thousandsofmonosaccharideunitsalljoinedtogetherbyglycosidic bonds.Theremainder ofthislecturewillfocusonmonosaccharides 4 Monosaccharides containinganaldehydearecalledaldoses,whilemonosaccharides carbonsthattheycontain.3carbon hexosesandsoon. 5 Fischer projectionsareausefulwaytorepresentthe3Ͳdimensionalstructureofsugarsin (analdopentose - asugarcontaining5carbonsandanaldehydefunctionalgroup).Onthe lefthandsideistheFischerprojection.This representsthe3ͲDviewshownon

1,2,3,4,and5

andhavethemolecularformulaC 5 H 10 O 5 6 SohowdoyouconverttheFischer projectionbackintoalineangledrawing,thatyouare ribbonview,youare bee?To

ͲHcomesour

goesbackawayfrom sugars importantinsugarchemistry. 7 Hopefully nowyoucanrecognizeAldosesfromKetoses,andnamethemaccordingtohow manycarbonstheycontain.Thealdopentose ontheleftwithanaldehydeand5carbons 8 Recallthataldehydesand ketoneshavedifferentoxidativepotential.Aldehydescanbe monomers.Sugarswithaldehydescanactasreducingsugars(ie asthey areoxidized,they reduction(orviceversa). 9 10 notcontaindetectablequantitiesofglucoseorothersugar monomers.However,indisease testforaldosesugarscanbeusedclinically totestforaldosesinurine.Notethatthis 11 Due tothehighnumberofchiralcenterswithinthesugarstructures,theygeneratealotof molecularformula.Theseareknownasconstitutionalorstructuralisomers(ie theyhave theatoms). 12 Sugarscanalsoformmanystereoisomers,ie thesugarshavethesamemolecularformula howmanychiralcentersthesugarhas.Itisbest toevaluateeverypossiblecarbonfor isdoublebondedtothecarbon,thecarbonis foundtobeachiralanddoesnotgeneratea stereocenter. 13 Movingdown,letsexaminecarbonͲ2. Thistime,weseethatcarbontwohasfourdifferent anddoesgenerateastereocenter. 14 chiral centersinglucose.Todeterminethenumberofstereoisomersusetheformula,2 n isomers. 15 Tolookatallthestereoisomers, wewillsimplifytheFischerprojectionsfurthertoRosanoff projections.InRosanoff projectionsonlythedirectionoftheOHgroupisgivenbythe theright,theleft,and therightandtheright. 16 Thepositionofthe-OHgrouptotherightorto theleftdesignatesthestereochemistryof thesugar. 17 Hereare the16stereoisomersofglucoseormorebroadly,aldohexoses. 18 Stereoisomerscanbeclassifiedfurtheraseitherdiastereomers orenantiomers. thattheyarethemirrorimageofthemolecule,butthat theyarenotsuperimposable. Diastereomers differatoneormorestereocenters,buttheyarenotopticalisomers(ie. They arenotmirrorimages). 19 Interestingly,you maynoticethattheenantiomerpairsaregiventheSAMEname!They

Theyeitherrotateitinthe

Thewrongstereoisomer

willnotbindanenzymeofinterest. 20

Eachsugarhasamirrorimageoranenantiomer

21
22
23
24
25
26
27
Insummary,enantiomerpairshavethesamemolecular formula,aremirrorimagesofone 28
atthechiralcenterthefarthest awayfromthemajorfunctionalgroup(thealdehydeorthe side,it 29
30
Howaboutthediastereomers?Thesearethestereoisomers thatdifferinoneormore chiralcenters,butarenotmirrorimages. 31
32
Notethatdiastereomer pairsall havethesameformula,buttheydohavedifferentphysical 33
34
Somediastereomers differonlyatoneposition,whileothersdifferatmultiple stereocenters. 35
epimers.Enzymesintheclassofisomerasesthatalteracompoundintoitsepimer are calledEpimerases. 36
ComebacktothisslideandtrytofindalloftheEpimer pairsofDͲallose.Youshouldfind four(sincetherearefourchiralcenters). 37
Hereisaslideofsomecommonaldosesinnature.You willneedtobeabletosite

DͲmannose,andDͲgalactose.

38
Youonlyneedtoknowtwoimportantketoses,dihydroxyacetone andDͲfructose. 39
Inthissection,youlearnedaboutimportant characteristicsofmonosaccharides.These drawing(althoughI 40
quotesdbs_dbs14.pdfusesText_20