10 hours of rehydration fluid by IV infusion The giving set delivers 20 drops/mL Calculate the drip rate Example 1: Drug Made Up From Stock Solution
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10 hours of rehydration fluid by IV infusion The giving set delivers 20 drops/mL Calculate the drip rate Example 1: Drug Made Up From Stock Solution
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DRUG-CALCS _20220927 Page 1 of 5
DRUG CALCULATIONS
© Student Learning Support Service, 2022
slss@flinders.edu.au students.flinders.edu.au/slss Identify what type of drug calculation and as a first step, use common sense to estimate a roughanswer. In many cases, drawing a picture that visually represents the problem is often a helpful strategy.
Remember that a formula often used for working out how many tablets to take or for a drug taken orally or injected is:VOLUME REQUIRED =
STRENGTH REQUIRED (SR)
xVOLUME OF STOCK
STOCK STRENGTH (SS) 1
Remember that a formula often used to work out the number of drops per minute delivered by an intravenous infusion is:DRIP RATE (DPM) =
VOLUME (mL) x DROPS/mL
TIME (h) x 60
Remember that for intravenous infusion, sometimes you are asked to calculate volume, time, or rate, and the following formulae can be useful:VOLUME (mL) =RATE (mL/h) x TIME (h)
RATEVOLUME (mL)
TIME =
VOLUME (mL)
TIME (h)
RATE (mL/h)
After applying the formula (if relevant), or calculating an exact answer using common sense, go back and check: is your final answer close to your initial estimate? If not, why not?EXAMPLE 1: DRUG MADE UP FROM STOCK SOLUTION
This example illustrates how to work out injections or orally taken drugs made up from stock solution
- for example, working out how many mLs to inject when the drug is in a stock solution.QUESTION: A patient is ordered 70 mg of pethidine. Find the volume required if the stock solution contains 10g
of pethidine per 200mL.TO SOLVE: We'll be using this formula:
VOLUME REQUIRED =
STRENGTH REQUIRED (SR)
x VOLUME OF STOCKSTOCK STRENGTH (SS) 1
1. Note down the strength of medication the patient needs and the stock strength:
Strength Required is 70 mg, Stock Strength is 10g in 200 mL At this point our rough answer is - More than 1 mL and a lot less than 200mL.2. Since you need units to be the same, convert 10 g to mg by multiplying by 1000.
e.g. 1000mg x 10 = 10,000mg (10,000mg = 10g)3. Now put the values into the above for.
Note that 70mg (what the patient needs) is a very small part of10,000mg - so expect your
answer in mL to be much less than 200mL ANSWER: Based on the above, your answer = 1.4mL VOLUME REQUIRED = 70x 200
mL = 14 14 mL = 1.4mL 10 1 10 10
HOW TO SOLVE DRUG CALCULATIONS
TIP: An easy way to
remember this formula isSUNRISE (SR)
SUNSET (SS)
NOTE: DPM stands for drops per minute CONVERSION TIP:X 1,000
g mg÷ 1,000
VISUAL
REPRESENTATION
10,000mg
PETHIDINE
200mLsolution