Figure 3 : Boucle d'auto-régulation des facteurs de transcription Nanog, Sox2 et Oct4 La figure de gauche montre que la dimérisation de Oct-4 et Sox2 a une
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[PDF] MS_2010_04_411pdf (1367Ko) - iPubli-Inserm
En 1989, le gène POU5f1 codant pour le facteur de transcription OCT4 (ou OCT3 /4) a été identifié chez la souris, dans les cellules souches embryonnaires
[PDF] Reprogrammation de cellules somatiques en cellules souches
Figure 3 : Boucle d'auto-régulation des facteurs de transcription Nanog, Sox2 et Oct4 La figure de gauche montre que la dimérisation de Oct-4 et Sox2 a une
Transcriptional Activation by Oct4 Is Sufficient for the - Cell Press
4 oct 2020 · Oct4 is an essential regulator of pluripotency in vivo and in vitro in embryonic stem cells, as well as a key mediator of the reprogramming of
Stem cell pluripotency and transcription factor Oct4 - Nature
Named Oct4, it can activate or repress the expression of various genes Curiously , very little is known about Oct4 beyond its ability to regulate gene expression
[PDF] Review Transcriptional regulation of the Oct4 gene, a - Digitum
4 oct 2020 · Oct4, Sox2 and Nanog constitute a triad of transcription factors that are critical for self-renewal and pluripotency of human and mouse embryonic
Analysis of Oct-4 expression and ploidy in individual human
In mice, a key factor for the first differentiation step in embryogenesis is the POU domain transcription factor oct-4, also named oct-3 (Okamoto et al , 1990;
[PDF] Role of Oct4 in the early embryo development - Cell Regeneration
Oct4, encoded by the gene Pou5f1, is a homeodomain transcription factor of the POU (Pit-Oct-Unc) family The POU family of transcription factors can activate the
[PDF] Oct4 protein remains in trophectoderm until late stages of mouse
blastocyst Oct-4 is downregulated in the trophectoderm (TE) and its expression becomes restricted to the inner cell mass (ICM) In order to determine the exact
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