[PDF] [PDF] ImageXpress Micro Confocal High-Content Imaging System

[PDF] ImageXpress Micro Confocal High-Content Imaging System

Higher quality images, faster throughput, and more powerful analysis The ImageXpress® Micro Confocal High-Content Imaging System provides improved  

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The ImageXpress® Micro Confocal High Content Imaging System from Molecular Devices is an integrated cellular See the MetaXpress High-Content Image Acquisition and Analysis Software Analysis Guide included Availability and cost

[PDF] ImageXpress Micro Confocal High-Content Imaging System

The ImageXpress® Micro Confocal High-Content Imaging System provides improved quantification for live or fixed cell assays This versatile imaging system  

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9 sept 2015 · ImageXpress Micro High Content Imaging System Options User Guide 4 5014166 D Note: For the ImageXpress Micro Confocal System, you can set the For specifications, ordering information, pricing, and sealing

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analyses are not limited to one type of HCS imaging system There appears to be roles for high content widefield and confocal systems; for whole-well scanning systems Price Ease of use Service and support Throughput Image analysis software Sensitivity/resolution ImageXpress Micro Confocal High-Content 

Automated Confocal Imaging and High-Content Screening for

ity of cells or cellular systems within reasonable time intervals using the traditional high throughput screening (HTS), as they apply to drug dis- covery, have advances in automation offer increasing rates of HTS throughput, the past few ImageXpress Coulter/ Assays based on 3D biological structures (micro- organs)

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ImageXpress Micro Confocal

High-Content Imaging System

The confocal solution for your complex biology

Higher quality images, faster throughput, and more powerful analysis The ImageXpress® Micro Confocal High-Content Imaging System provides improved quantification for live or fixed cell assays. This versatile imaging system features a unique confocal technology which allows you to explore more physiologically relevant, complex three dimensional models including spheroids, tissues, and whole organisms and to generate publication quality images at high throughput for samples in slides or one to 1536-well microplates. For researchers looking to expand their laboratory"s capabilities, the ImageXpress Micro Confocal system leverages large field-of- view optics to map macro-structures with minimal tiling. In addition, querying of large cell populations is accelerated, speeding up the characterization of highly heterogeneous samples or identification of rare subpopulations.

KEY FEATURES

Acquire statistically relevant data quickly

with an advanced scientific CMOS detector, enabling >3 log dynamic range

Improve visualization and quantitation

with 3D assay models

Achieve excellent image quality without

sacrificing throughput using our unique optical path technology

Expand your research capabilities with

transmitted light, liquid handling, and environmental options Combined with MetaXpress High-Content Image Acquisition and Analysis Sof tware, the ImageXpress Micro Confocal system is a complete solution that enables you to interpret your images, understand your data , and explore new ideas - in both widefield and confocal modes. B enefits

Introduction

in vitro in vivo

APPLICATION

NOTE

Spheroid formation

and treatment B enefits

Introduction

in vitro in vivo

APPLICATION NOTE

Spheroid formation

and treatment W id e field and Confo c a l

Contact Us

Phone: +1.800.635.5577

Web: www.moleculardevices.com

Email: info@moldev.com

Check our website for a current listing

of worldwide distributors. The trademarks used herein are the property of Molecular Devices, LLC or their respective owners. Specifications subject to change without notice. Patents: www.moleculardevices.com/patents FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES. ©2018 Molecular Devices, LLC

8/18 1972

Printed in USA

System

• High-speed laser autofocus with integrated image autofocus option • Linear encoded voice coil driven X, Y, and Z stages with < 25 nm resolution •4-position automated objective changer* •5-position software selectable dichroic filter wheel* •8-position software selectable emission filter wheel* • Sample compatibility: slides and one to 1536-well microplates, round or flat bottom, low to high profile, and trans-well plates

AgileOptix Optical Path

• AgileOptix technology enables the ImageXpress Micro Confocal system to deliver the sensitivity and throughput needed for demanding applications by combining a powerful solid-state light engine, high-quantum efficiency 16-bit scientific CMOS sensor and selectable unique confocal geometries. •>3 log dynamic range in both widefield and confocal modes • Large field of view (1.96 mm 2 at 10X) imaging to maximize collection of publication quality images and statistically relevant data *user changeable

OptionFeature

Environmental

control• Multi-day, live cell time-lapse imaging • Provides appropriate atmospheric conditions (e.g. 5% or 10% CO 2 • Mimics physiological environment (30-40 °C ± 0.5 °C) • Controls humidity and minimizes evaporation (0.5 L/well/hour for 96- or 384-well formats) Phase contrast• High contrast imaging where unstained cells are easily viewed or separated from background (4X-60X) • Ideal for non-fluorescent histochemically stained samples • Nikon 100W Pillar Diascopic Illuminator with TE-C

ELWD Condenser

• 0.3 NA with 65 mm WD and PhL, Ph1, and Ph2 selectable phase rings • Fluorophore-independent morphology visualization with fluorescent imaging overlay

Liquid handling

• Single-channel pipettor • Dispense volumes from 3 L to 200 L (±1 L; ±5%) • Compatible with 96- or 384-well format FLIPR

System pipette tips

• Holds two plates for compound addition or media exchange • Optional plate heating • Environmental control Note: all options, filters, and objectives are available at point of sal e or as after market upgrades. Configuration shown in this datasheet do not encompass all configurations available. Contact your sales and support team today to identify the system configuration most suitable fo r your applications.

Specifications

4X Acquire greater than 200,000 wells per day at 4x magnification with the system's unique multi-well crop feature.

Explore modifications with AWES

The Molecular Devices Advanced Workflow Engineering Solution (AWES) team has successfully tailored the ImageXpress Micro system for some customers to include a variety of light engines to address ultra violet (UV) to near infrared (NIR) applications, environmental control with gas mixers for CO 2 and Hypoxia, fluidics with simultaneous imaging and dispensing, as well as integration of other lab components such as incubators, liquid handlers, and robotics for a fully automated work cell. The AWES team is available to explore these modifications with you. Price, time to deliver, and specifications will vary based on mutually agreed technical requirements. Solution requirements may cause adjustment to standard performance. Purchase Terms available atquotesdbs_dbs12.pdfusesText_18