25 fév 2013 · Respiratory Society Annual Congress 2013 ERS Membership Number: 4052 Other Memberships: ERS to participate in Title: Similar
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European Respiratory Society Annual Congress 2013
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European Respiratory Society Annual Congress 2013
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25 fév 2013 · Respiratory Society Annual Congress 2013 ERS Membership Number: 4052 Other Memberships: ERS to participate in Title: Similar
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Please select Print from the file menu to print your Abstract.European Respiratory SocietyAnnual Congress 2013Abstract Number: 851870Contact/Presenting Author: Prof. Maria R BonsignoreDate of Birth (dd/mm/yyyy): 01/03/1956Is the presenting author a Medical Doctor (MD)? YesERS Membership Number: 4052Other Memberships:ACCP - American College of Chest PhysiciansATS - American Thoracic SocietyOther - AASM, ESRSDepartment/Institution: DiBiMIS, Section of Pneumology, University of PalermoAddress: Via Trabucco 180City/State/Zip/Country: Palermo, 90146, ItalyPhone: +393287538815 Fax: +390916882842 E-mail: marisa@ibim.cnr.itAbstract Group: 4.1. Clinical respiratory physiology, exercise and functional imagingKeyword 1: Exercise Keyword 2: Cell biology Keyword 3: PhysiologyPRESENTATION TYPE: No preference selected.You have only applied for the grants and/or sponsorships displayed below:General Conflicts of Interests: The Presenting Author has no, real or perceived conflicts of interest that relateto this abstract.Tobacco-Industry related conflict of interests: I have NO relationship of any kind with the tobacco industry(since 1/1/2000) nor will have a link to the tobacco industry before the event to which I have been invited by theERS to participate inTitle: Similar cellular composition of induced sputum in Marathon and Half-Marathon runnersProf. Maria R Bonsignore, marisa@ibim.cnr.it, MD1,2, Dr. Rosalia Gagliardo, gagliardo@ibim.cnr.it2, Dr. AlessandraPaterno', a.paterno@yahoo.it1, Dr. Simonetta Bono, simonetta.bono@gmail.com1, Dr. Loredana Riccobono,riccobono@ibim.cnr.it2, Dr. Roberta Santagata, robertasant@katamail.com1, Dr. Danila Rinoldo,rinoldodanila@libero.it1, Dr. Michele Davì, m.davi1973@libero.it1, Dr. Anna Bonanno, bonanno@ibim.cnr.it2, Prof.Nicola Scichilone, nicola.scicilone@unipa.it, MD1, Dr. Mirella Profita, profita@ibim.cnr.it2 and Dr. Giuseppe Morici,
gfme.morici@tin.it, MD2, 3. 1DiBiMIS, Section of Pneumology, University of Palermo, Palermo, Italy, 90146; 2IBIM,CNR, Palermo, Italy, 90146 and 3BioNeC, Section of Physiology, University of Palermo, Palermo, Italy, 90134.Body: In our previous studies, we reported increased neutrophil (PMN) differential counts in induced sputum ofmarathon (M) runners (Bonsignore et al, 2001). Conversely, increased bronchial epithelial cell (BEC) differentialcounts were found in half-marathon (HM) runners (Chimenti et al, 2010). To better understand the differencespreviously found between M and HM runners, we studied 11 non-asthmatic amateur athlet
es (HM n=6, M n=5,age: 44.5±6.7 yrs, race time: HM 101±18 min, M 218±35 min) participating to the 2012 Palermo Marathon. Wecollected induced sputum samples 4 to 5 days before the race (PRE), 2 hours after the race (RACE), and thefollowing morning (POST). Induced sputum was processed according to the plug technique. Results are shown inthe table (means±SD).Differential cell counts of BEC and PMN in induced sputum PMN HM%PMN M%BEC HM %BEC M%PRE19.014.524.320.33.97.70.30.5RACE47.819.9*48.317.4*28.413.821.910.6European Respiratory Society Annual Congress 2013 : Abstra...http://www.call4abstracts.com/ers/finalpreview.php?absnum...1 di 225/02/13 14:25brought to you by COREView metadata, citation and similar papers at core.ac.ukprovided by Archivio istituzionale della ricerca - Università di Palermo
POST51.518.4*50.711.3*2.11.65.32.3* p<0.05 vs PRE, § p<0.05 vs PRE and POSTIn both HM and M runners, PMN differential counts increased from PRE to RACE and remained elevated in POST,whereas BEC differential counts increased from PRE to RACE, but returned to baseline at POST. These preliminaryresults indicate that BEC damage, possibly induced by hyperosmolar exposure during exercise hyperpnea, occursfor the entire duration of endurance exercise but is transient. Conversely, PMNs were recruited in the airways for alonger time, possibly secondary to chemiotactic stimuli released by BEC during exercise. Lack of differencesbetween HM and M runners suggests that duration of the endurance race does not affect the airway cell responseto exercise.Close WindowEuropean Respiratory Society Annual Congress 2013 : Abstra...http://www.call4abstracts.com/ers/finalpreview.php?absnum...2 di 225/02/13 14:25
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