18 avr 2016 · Topo1-ccs or Topo2-ccs are removed by tyrosyl-DNA phosphodiesterase-1 or -2 (TDP1 or TDP2), after proteolysis of Topos into small peptide
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[PDF] Y-box binding protein 1 enhances DNA topoisomerase 1 - CORE
Methods: The direct association of TOPO1 with specific domain of YB-1 was explored by co-immunoprecipitation and GST pull-down assays The interaction
[PDF] Examination of Topoisomerase I (TOPO1) Expression in Metastatic
Figure 4A-H Representative Images of H&E and IHC staining for TOPO1 (A-B) colorectal cancer metastatic to the lung, 3+ 90 ; (C-D) pancreatic cancer
TOPO1-23B11 - Nanotools
Mab TOPO1-23B11 specifically recognizes Topoisomerase 1 in Western blot applications All products are supplied for research and investigational use only
SUMO-1 conjugation to intact DNA topoisomerase I - Nature
as Topo1 sumoylation sites, reduced the CPT-induced cleavable complexes without influencing its in vitro catalytic activity Consistent with this observation,
[PDF] Tyrosyl-DNA Phosphodiesterase I a critical survival factor for
(TOPO1-cc) explicitly in neuronal tissue during development TDP1 resolves 3'- and 5'-DNA adducts including trapped TOPO1-cc and TOPO1 protease resistant
Thymidylate Synthase, Topoisomerase-1 and Microsatellite Instability
Conclusion: Our data suggest the TOPO1 expression levels to be a prognostic marker in patients with mucinous CRC treated with FU If further verified, these data
Metalloprotease SPRTN/DVC1 Orchestrates Replication - Cell Press
18 avr 2016 · Topo1-ccs or Topo2-ccs are removed by tyrosyl-DNA phosphodiesterase-1 or -2 (TDP1 or TDP2), after proteolysis of Topos into small peptide
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