One of the best methods to synthesize carboxylic acids is the hydrolysis (acid- or base-catalyzed) of nitriles which occurs in two steps through the intermediate amide (eq Thus, the relative rates of nitrile hydrolysis correlate linearly with anticipated nitrile basicity
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The Acid-Catalyzed and Uncatalyzed Hydrolysis of Nitriles on
One of the best methods to synthesize carboxylic acids is the hydrolysis (acid- or base-catalyzed) of nitriles which occurs in two steps through the intermediate amide (eq Thus, the relative rates of nitrile hydrolysis correlate linearly with anticipated nitrile basicity
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Hydrolysis of carboxylic acid esters, amides, and nitriles can be either catalyzed by acid or base Synthesis by nitrile hydrolysis is widely employed because the
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Acid-Catalyzed Ester Hydrolysis Because esterification of an acid with an alcohol Nitriles are hydrolyzed to carboxylic acids and ammonia by heating them in
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